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College of Cultural Sciences Announces Results for 6th Best Paper Award
The College of Cultural Sciences cohosts with the EFL Program the Best Paper Award each semester. The Best Paper Awards went to Jo Hyeong Chan and Oh Shin Ah undergraduate students. The Best Paper Award was established in 2009 in order to encourage and improve the English writing skills of undergraduate students.
The College of Humanities and Social Sciences opened up 69 English courses in Spring of 2012 and 14 papers were recommended by the respective professors as ‘best papers’. Out of these papers 2 were selected for First Prize and 4 were selected as Honorable Mentions. The two recipients’ papers were recommended by Professor Park Woo Seok (Topics in Philosophy).
2012.10.16 View 7001 -
DNA based semiconductor technology developed
Professor Park Hyun Gyu’s research team from the Department of Chemical and Biomolecular Engineering at KAIST has successfully implemented all logic gates using DNA, a feat that led the research to be published as the cover paper for the international nanotechnology paper "Small".
Even with the latest technology, it was impossible to create a silicon based semiconductor smaller than 10nm, but because DNA has a thickness of only 2nm, this could lead to the creation of semiconductors with groundbreaking degrees of integration.
A 2 nm semiconductor will be able to store 10,000 HD movies within a size of a postage stamp, at least 100 times more than the current 20nm semiconductors.
DNAs are comprised of 4 bases which are continually connected: Adenine (A) with Thymine (T), and Guanine (G) with Cytosine (C).
For this research, the team used the specific binding properties of DNA, which forms its helix-shape, and a circular molecular beacon that has fluorescent signaling properties under structural changes.
The research team used input signals to open and close the circular DNA, the same principle that is applied to logic gates in digital circuits.
The output signal was measured using the increase and decrease of the fluorescent signal from the molecular beacon due to the opening and closing of the circular DNA respectively.
The team overcame the limited system problems of the existing logic gates and managed to implement all 8 logic gates (AND, OR, XOR, INHIBIT, NAND, NOR, XNOR, IMPlCATION). A multilevel circuit that connects different logic gates was also tested to show its regenerative properties.
Professor Park said that “cheap bio-electric devices with high degrees of integration will be made possible by this research” and that “there will be a large difference in the field of molecular level electronic research”
Mr. Park Gi Su, a doctoral candidate and the 1st author of this research, said that “a DNA sequence of 10 bases is only 3.4nm long and 2nm thick, which can be used to effectively increase the degree of integration of electronic devices” and that “a bio computer could materialize in the near future through DNA semiconductors with accurate logic gates”.
XOR Gate: The output signal 1 comes through the open circular DNA when either input DNA A or input DNA B is present. When both inputs are not present, the flourescent signal does not come through
2012.09.27 View 9059 -
Professor Moon Song Chun appointed representative director of European IT society
Professor Moon Song Chun from the College of business at KAIST was appointed as the representative director of Asia for the European IR society EUROMICRO at its 35th general meeting in Lille, France.
Professor Moon is highly regarded in his work in popularization of IT in 3rd world countries and has published the largest number of papers in the history of EUROMICRO. For the next two years, Professor Moon will work to introduce Asia’s IT capabilities to the world and to increase the recognition of the society in the region.
Professor Moon, who is also known as the first Computer Science Doctor (PhD) in Korea, has worked to popularize IT by initiating IT volunteer services in Africa, the Middle East, Central and South America, South East Asia and Eastern Europe. He has also helped in the recognition of Korea’s IT capacity, working as a Korean Delegate for the UN International Y2K Cooperation Center, a Distinguished Scholar at Hungarian Academy of Sciences, and a Visiting Scholar at Cambridge University.
2012.09.25 View 8201
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Professor Soon-Heung Chang meets with Bill Gates and discusses possible collaboration
Professor Soon-Heung Chang from the Department of Nuclear and Quantum Engineering, KAIST, who is also the president of Korea Nuclear Society (KNS), met Bill Gates, the co-founder and former chief executive officer (CEO) of Microsoft, on August 16, 2012 and discussed ways to cooperate for the development of a sodium-cooled fast reactor (SFR), a next generation nuclear power reactor.
According to Professor Chang, Bill Gates was amazed at Korea’s successful bids for nuclear power plants in the United Arab Emirates, even though Korea was a latecomer in the field of nuclear power. Bill Gates also showed a keen interest in Korea’s low electricity rates.
Gates focuses on solving fundamental problems in order to help improve the quality of life for humanity, rather than short-term temporary solutions, through infrastructure development such as energy. Particularly, he considers nuclear power as one of the most effective ways to supply clean energy which can provide electricity at a low cost while keeping carbon dioxide emission levels much lower than fossil fuels.
Bill Gates is a primary investor for an energy company called “TerraPower” based in Bellevue, Washington. TerraPower develops and commercializes nuclear power technology for a traveling wave reactor (TWR) that is designed to use spent fuels, i.e., depleted uranium, and runs technically “forever” because once fueled, the reactor does not need to be refueled for over 50 years. TerraPower’s TWR is to use metallic fuel, and Korea is the only country that currently develops SFR (KALIMER 600) using metallic fuel.
“Korea has an outstanding supply chain for the entire lifecycle of a nuclear power station from equipment manufacturing to operation,” said Professor Chang, while emphasizing the synergistic effects of forming partnership between Korea and TerraPower.
Professor Chang emphasized that Korea should create an opportunity based on lessons learned from the Fukushima crisis and actively move forward to achieve its leading position in the field of next generation nuclear reactors. He said that cooperation with Bill Gates will be a significant step towards the development of next generation nuclear reactors.
About Sodium-cooled Fast Reactor (SFR)
Sodium-cooled Fast Reactor (SFR) is a next-generation nuclear power reactor that will use spent fuels from conventional reactors. Arrangement of a fuel recycling system in
conjunction with currently-developing pyroprocessing technology would enable U-238, which makes up over 99% of natural uranium, to be used as a nuclear fuel. This would greatly reduce the toxicity and volume of spent fuels by up to 1,000 times and 100 times respectively when compared to existing reactors. This is truly a breakthrough innovation in spent fuel disposal and recycling.
2012.09.20 View 10003 -
Liver Damage Mechanism of Hepatitis C Proven
KAIST researchers found mechanics behind a Hepatitis C virus, thereby taking a step closer to the development of a cure for Hepatitis C.
Professor Choi Chul Hui (Department of Biological and Brain Engineering) and Professor Shin Eui Chul (Graduate School of Medical Sciences) proved, for the first time in the world, the mechanism behind liver damage of a patient with Hepatitis C.
It is anticipated that this discovery will allow for the development of a Hepatitis C cure that has no side effects and little Liver damage.
Hepatitis C is an immune response of the body to the Hepatitis C virus and causes liver irritation.
Around 170million people are infected with Hepatitis C worldwide including 1% of the Korean population. Once infected, most cases turn into chronic cases and may lead to liver cancer.
However it was impossible to infect Hepatitis C within a test tube cell environment until 2005 and up till then Chimpanzees were used to study the virus which proved to be a huge barrier to research.
The research team used cells infected with Hepatitis C virus and found out that the virus works by increasing the destruction of cells by the TNF-a protein responsible for the cell’s immune response.
In addition the protein structure of the virus that causes this reaction was successfully found.
Conventionally the Hepatitis C medication focused on the suppressing the growth of the virus and therefore had many side effects.
The experimental results allow new medication aimed at suppressing the actual mechanism of liver damage to be discovered.
The result was selected as the cover dissertation of the September Edition of the Hepatolog magazine.
2012.09.11 View 11477
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First Annual CanSat Idea Exhibition held
The Ministry of Education, Science, and Technology held the ‘CanSat’ Exhibition in order to increase interest and understanding of satellites in primary, secondary, and high school level students.
The exhibition, hosted by KAIST Satellite Research Center and funded by Korea Aerospace Institute, was held in SaeJeong City.
90 primary, secondary school teams, 57 high school teams, and 14 university teams submitted their applications for participation. Of these teams 20 primary, secondary school teams, 5 high school teams, and 5 university teams were selected after thorough document valuation and presentation assessment.
The 20 primary, secondary school teams participated in the science camp to gain firsthand experience in the construction and launch of a simple satellite system.
The high school and university teams were evaluated by the level of completion of the task given and the level of creativity involved.
The CanSat Exhibition has been held in aerospace powerhouses and this was the first time such an exhibition was held in Korea.
2012.08.21 View 8259
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Successful development and analysis of mesoporous quasicrystal structures
Professor Osamu Terasaki’s research team from the EEWS Graduate School at KAIST successfully synthesized mesoporous quasicrystalline silica and developed a new method of analyzing its growth. The theory proposed by the team laid the foundation for the scientific examination of quasicrystal phenomena during the formation of micelles particles, a type of soft matter. The paper was published in the July edition of Nature magazine.
Scientists have faced difficulty in systematically explaining the mesoporous quasicrystal structures that are found in solidified versions of soft matter systems. However, the theoretical foundation from this research is expected to help promote the research and development of new nano-structured materials.
Mesoporous quaicrystals are soft matters that have high symmetry and a larger characteristic length scale than the nanoscale, thereby making it possible to develop materials that have controllable optical properties. This technology can be applied to the sustainable storage, use, and reproduction of energy.
Professor Terasaki’s team succeeded in synthesizing mesoporous quasicrystalline silica and proved the formation of dodecagonal column-shaped crystals as well as dodecagonal, rotationally symmetric electron diffraction patterns near the crystals using Transmission Electron Microscopy.
Quasicrystals are an abbreviation of ‘quasiperiodic crystals’ and have what is called the ‘third solid’ property; they have a structural arrangement that is between arranged crystal structures, such as metals, and non-crystalline structures, such as glass. This crystalline structure was only recently found, and the 2011 Nobel Chemistry Award was given to research in this field.
When porous materials are synthesized into quasicrystals, the crystalline structures of the pores can be designed and controlled in any way, making it possible to create new materials for a wide range of fields.
Professor Terasaki said that ‘The discovery of highly symmetric quasicrystals can lead to the alteration of a material’s optical properties, allowing the development of photonic crystals in the visible spectra.’ He also explained that this control of a material’s optical energy absorption could be the core technology behind energy harvesting.
This research was jointly conducted by Professor Terasaki from the EEWS Graduate School at KAIST and Stockholm University in Sweden.
2012.08.01 View 8475
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Professor Bae Sang Min Wins Multiple Prestigious Design Awards
Summer is perfect for many outdoor activities, but it is also the season for mosquitoes, an annoying pest that makes outdoor experiences unpleasant and sometimes even dangerous. An easy-to-use and environmentally-friendly spray, “Sound Spray” (http://idsa.org/soundspray-self-generating-non-toxic-ultrasonic-anti-mosquito-spray), which repels mosquitoes by setting off ultrasonic waves, has been developed by a research team at KAIST. The spray produces sounds similar to those of mosquitoes’ natural predators.
Sound Spray made the list of finalists in the category of "Social Impact Design" from the 2012 International Design Excellence Awards (IDEA). The IDEA is one of the most renowned design competitions in the world, which has been held annually by the Industrial Designers Society of America (IDSA).
Inside Sound Spray is a battery that generates electricity when a user shakes the spray bottle. Electrical energy produced by the battery creates an ultrasonic sound that mosquitoes dislike, thereby discouraging their contact with human skin. Professor Sangmin Bae from the Department of Industrial Design at KAIST explains,
“In regions such as Africa or Southeast Asia, mosquitoes are still posing a big threat to public health. Unlike Freon-based, disposable insect repellents on the market, Sound Spray is eco-friendly, easy to carry around, reusable, and affordable. I plan to commercialize and distribute it to nations in Africa or Southeast Asia to help them combat against malaria, an infectious disease that patients contract through mosquito bites.”
Professor Bae also received another award from the 2012 IDEA in the area of Commercial and Industrial Products: a bronze medal for a milling machine, the Namsun Milling Machine (http://www.idsa.org/namsunnew-innovative-milling-machine-design). The machine has large windows on each side of its main body that display a transparent workflow so that users easily understand the machine’s operation status. Curved lines are actively used for the exterior design of the machine to create a more friendly work environment.
In addition to the 2012 IDEA, Professor Bae has participated in other major international design awards, including the Red Dot Award, the If Design Award Japan, and the Good Design Award, from which his research team has received a total of 41 prizes.
Professor Bae initiated a campaign in 2005 called “Philanthropy Design,” through which he has donated many of his designs to help people in need. For more on his research, please visit http://www.coroflot.com/frame29/Portfolio1.
2012.07.26 View 11472 -
KAIST researchers verify and control the mechanical properties of graphene
KAIST researchers have successfully verified and controlled the mechanical properties of graphene, a next-generation material. Professor Park Jung Yong from the EEWS Graduate School and Professor Kim Yong Hyun from the Graduate School of Nanoscience and Technology have succeeded in fluorinating a single atomic-layered graphene sample and controlling its frictional and adhesive properties. This is the first time the frictional properties of graphene have been examined at the atomic level, and the technology is expected to be applied to nano-sized robots and microscopic joints.
Graphene is often dubbed “the dream material” because of its ability to conduct high amounts of electricity even when bent, making it the next-generation substitute for silicon semiconductors, paving the way for flexible display and wearable computer technologies. Graphene also has high potential applications in mechanical engineering because of its great material strength, but its mechanical properties remained elusive until now.
Professor Park’s research team successfully produced individual graphene samples with fluorine-deficiency at the atomic level by placing the samples in Fluoro-xenon (XeF2) gas and applying heat. The surface of the graphene was scanned using a micro probe and a high vacuum atomic microscope to measure its dynamic properties.
The research team found that the fluorinated graphene sample had 6 times more friction and 0.7 times more adhesiveness than the original graphene. Electrical measurements confirmed the fluorination process, and the analysis of the findings helped setup the theory of frictional changes in graphene.
Professor Park stated that “graphene can be used for the lubrication of joints in nano-sized devices” and that this research has numerous applications such as the coating of graphene-based microdynamic devices.
This research was published in the online June edition of Nano Letters and was supported by the Ministry of Science, Technology, and Education and the National Research Foundation as part of the World Class University (WCU) program.
2012.07.24 View 14189 -
Systems biology demystifies the resistance mechanism of targeted cancer medication
Korean researchers have found the fundamental resistance mechanism of the MEK inhibitor, a recently highlighted chemotherapy method, laying the foundation for future research on overcoming cancer drug resistance and improving cancer survival rates. This research is meaningful because it was conducted through systems biology, a fusion of IT and biotechnology.
The research was conducted by Professor Gwang hyun Cho’s team from the Department of Biology at KAIST and was supported by the Ministry of Education, Science and Technology and the National Research Foundation of Korea.
The research was published as the cover paper for the June edition of the Journal of Molecular Cell Biology (Title: The cross regulation between ERK and PI3K signaling pathways determines the tumoricidal efficacy of MEK inhibitor).
Targeted anticancer medication targets certain molecules in the signaling pathway of the tumor cell and not only has fewer side effects than pre-existing anticancer medication, but also has high clinical efficacy. The technology also allows the creation of personalized medication and has been widely praised by scientists worldwide.
However, resistances to the targeted medication have often been found before or during the clinical stage, eventually causing the medications to fail to reach the drug development stage. Moreover, even if the drug is effective, the survival rate is low and the redevelopment rate is high.
An active pathway in most tumor cells is the ERK (Extracellular signal-regulated kinases) signaling pathway. This pathway is especially important in the development of skin cancer or thyroid cancer, which are developed by the mutation of the BRAF gene inside the path. In these cases, the MEK (Extracellular signal-regulated kinases) inhibitor is an effective treatment because it targets the pathway itself. However, the built-up resistance to the inhibitor commonly leads to the redevelopment of cancer.
Professor Cho’s research team used large scale computer simulations to analyze the fundamental resistance mechanism of the MEK inhibitor and used molecular cell biological experiments as well as bio-imaging* techniques to verify the results.
* Bio-imaging: Checking biological phenomena at the cellular and molecular levels using imagery
The research team used different mutational variables, which revealed that the use of the MEK inhibitor reduced the transmission of the ERK signal but led to the activation of another signaling pathway (the PI3K signaling pathway), reducing the effectiveness of the medication. Professor Cho’s team also found that this response originated from the complex interaction between the signaling matter as well as the feedback network structure, suggesting that the mix of the MEK inhibitor with other drugs could improve the effects of the targeted anticancer medication.
Professor Cho stated that this research was the first of its kind to examine the drug resistivity against the MEK inhibitor at the systematic dimension and showed how the effects of drugs on the signaling pathways of cells could be predicted using computer simulation. It also showed how basic research on signaling networks can be applied to clinical drug use, successfully suggesting a new research platform on overcoming resistance to targeting medication using its fundamental mechanism.
2012.07.06 View 10491
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New wireless charging device developed
The On-line Electric Vehicle (OLEV) developed by KAIST has made a step towards commercialization with the development of a more economic wireless charging device.
Professor Chun-Taek Rim from the Department of Nuclear and Quantum Engineering at KAIST has developed a new I-shaped wireless charging device that differs from the pre-existing rail-type electricity feeder. This device can be modularly produced and requires relatively less construction, significantly reducing the cost of implementation.
The KAIST OLEV is a new concept electric car that has a special electricity collecting device underneath it. The car’s battery is charged by magnetic fields produced from electric lines buried 15cm underneath the road. The vehicle was first tested in 2009, making it the first wireless electric car in the world. OLEV can be charged during stoppage time between traffic lights and receives real-time power when running. OLEV is currently in operation at the KAIST Munji Campus in Daejeon and is also being exhibited at the Yeosu Expo and Seoul Grand Park.
The device itself has a charging capacity of 15kW, and the electricity is supplied through an electricity feeder with a width of 80cm with a space interval of 20cm. Despite being hailed as a technological breakthrough and revolutionary concept, KAIST OLEV has been criticized for problems in commercialization, due to the difficulties in installing wires beneath existing roads, which costs a considerable amount of money.
The new I-shaped wireless charging device reduces the width of the electricity feeder by 10cm, a mere one-eighth of the size of the previous version, and greatly increases the charging power to 25kW. Furthermore, the left and right permissible space of automobiles has increased to 24cm and the magnetic field complies with the international design guidelines, making the OLEV safe for the human body.
The reduction of the width has made the mass production of modules possible, making the installation of KAIST OLEV more economical and marketable. Professor Rim emphasized that compared with the existing rail-type electricity feeder, the new technology will need only one-tenth of the construction time and 80% of the cost, significantly improving OLEV’s constructability and workability.
The research was published in the IEEE Transactions on Power Electronics last December, and Professor Rim was invited to talk at the Conference on Electric Roads & Vehicles, which was held in February in the United States, about the new technology.
2012.07.06 View 10796
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The hereditary factor of autism revealed
Korean researchers have successfully investigated the causes and hereditary factors for autistic behavior and proposed a new treatment method with fewer side effects.
This research was jointly supported by the Ministry of Education, Science and Technology and the National Research Foundation as part of the Leading Researcher and Science Research Center Program
The research findings were publishing in the June edition of Nature magazine and will also be introduced in the July edition of Nature Reviews Drug Discovery, under the title ‘Autistic-like social behavior in Shank2-mutant mice improved by restoring NMDA receptor function’.
The research team found that lack of Shank2 genes in mice, which are responsible for the production of synapse proteins, caused autistic-like behavior. The results strongly suggested that the Shank2 gene was linked to autistic behavior and that Shank2 deficiency induced autistic behaviors.
Autism is a neural development disorder characterized by impaired social interaction, repetitive behavior, mental retardation, anxiety and hyperactivity. Around 100 million people worldwide display symptoms of autistic behavior. Recent studies conducted by the University of Washington revealed that 1 out of 3 young adults who display autistic behavior do not fit into the workplace or get accepted to college, a much higher rate than any other disorder. However, an effective cure has not yet been developed and current treatments are limited to reducing repetitive behavior.
The research team confirmed autistic-like social behavior in mice without the Shank2 genes and that the mice had decreased levels of neurotransmission in the NMDA receptor. The mice also showed damaged synaptic plasticity* in the hippocampus**.
* Plasticity: ability of the connectionbetween two neurons to change in strength in response to transmission of information
**Hippocampus: part of the brain responsible for short-term and long-term memory as well as spatial navigation.
The research team also found out that, to restore the function of the NMDA receptor, the passive stimulation of certain receptors, such as the mGLuR5, yielded better treatment results than the direct stimulation of the NMDA. This greatly reduces the side effects associated with the direct stimulation of receptors, resulting in a more effective treatment method.
This research successfully investigated the function of the Shank2 gene in the nerve tissue and showed how the reduced function of the NMDA receptor, due to the lack of the gene, resulted in autistic behavior. It also provided new possibilities for the treatment of autistic behavior and impaired social interaction
2012.06.24 View 10818