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Professor Sung Yong Kim Appointed as Committee Member to Serve PICES
The Pacific International Council for the Exploration of the Sea: North Pacific Marine Science Organization (PICES) is an intergovernmental organization, which was established in 1992 to promote and coordinate marine research in the North Pacific and adjacent areas. Currently, the United States, Canada, Japan, China, Russia, and Korea are members of the organization. Professor Sung Yong Kim of Ocean Systems Engineering, KAIST, has been appointed to serve the Scientific and Technical Committees of PICES. He will begin his stint from July 1, 2014. During his assignment, Professor Kim will identify the need for observation of the North Pacific marine environment, develop observation methodology, and publish an annual report on the observation. Professor Kim is an expert in marine physics and environmental fluids, with a focus on coastal circulation and dynamics, mesoscale and submesoscale eddies, integrated coastal ocean observing system, and statistical and dynamic data analysis.
2014.06.18
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Professor Sang-Ouk Kim's Research on Carbon Materials Featured in a Philippines Science News
The subject article said that Professor Sang-Ouk Kim of Materials Science Engineering at KAIST “developed a technique to change the nature of the next-generation carbon-based materials. His research has expanded the possibility of carbon-based materials to be used in clothes.” For details, please refer to the article below: Centrio Times, June 10, 2014 KAIST scientist develops color changing carbon materials that can be used in clothes http://www.centriotimes.com/2014/06/kaist-scientist-develops-color-changing-carbon-materials-can-used-clothes.html.
2014.06.15
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Professor Ki Jun Jeong Selected As the Winner of the 'Young Asian Biotechnologist Prize'
Professor Ki Jun Jeong from the Department of Chemical and Biomolecular Engineering, KAIST, has been selected as the winner of this year’s Young Asian Biotechnologist Prize. Professor Jeong was invited to the 66th Japan Biotechnology and Bioengineering Society Conference scheduled in September 9th-11th, 2014, in Sapporo, Japan, where his award ceremony will be held. The award is presented to Professor Jeong in recognition of his outstanding research on microbial-based production of antibodies and efficiency improvement. The Young Asian Biotechnologist Prize is awarded annually by the Japan Biotechnology and Bioengineering Society to the researchers in Asia under the age of 45, who have achieved excellent research results in the field of bioengineering.
2014.06.14
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A mechanism for how reactive oxygen species cause cell responses studied
A research team led by Professor Kwang-Hyun Cho of the Department of Biology and Brain Engineering, KAIST, and Dr. Gi-Sun Kwon of the Korea Research Institute of Bioscience and Biotechnology succeeded in proving the mechanism behind the determination of cell life in relation to reactive oxygen species. The results of the venture were published in the June 3rd edition of Science Signaling. The title of the research paper is “MLK3 is part of a feedback mechanism that regulates different cellular responses to reactive oxygen species.” The research team discovered that the molecular switch that determines the division of apoptosis of a cell was based on MLK3 feedback mechanism. MLK stands for mixed-lineage kinase. Under sufficient stress, the mechanism instructs the cell to undergo the division but in an overly stressful environment, the mechanism stops the cell division and instead, induces apoptosis. This discovery is expected to be a breakthrough in illnesses related to the concentration of the reactive oxygen species (ROS). At low concentration of ROS, the protein associated with cell division, ERK (extracellular-signal-regulated kinase), is activated while as the ROS concentration increases, JNK (c-Jun N-terminal protein kinases), responsible for apoptosis, becomes activated. Furthermore, through computer simulation analysis and mathematical modeling, in tandem with molecular cell biology experiments, the MLK3 based feedback mechanism was the fundamental molecular switch that determines the balance between ERK and JNK, and ultimately the cell’s responses. Professor Cho commented that “the contradicting cell responses to ROS had remained a mystery, but with the system biology, an approach in which information technology and biotechnology converge, such riddles can be resolved. We expect that the proven mechanism will be used to overcome aging or cancer growth as a result of ROS in the near future.” Picture shows the process of identifying cell responses caused by reactive oxygen species.
2014.06.13
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An Exploratory Study on Smartphone Abuse among College Students
Professor Uichin Lee Professor Uichin Lee of the Department of Knowledge Service Engineering, KAIST, and his research team developed a system that automatically diagnoses the levels of smartphone addiction based on an analysis of smartphone use records. Professor Lee investigated the usage patterns of 95 smartphone users (college students) by conducting surveys and interviews and collecting logged data. The research team divided participants into “risk” and “non-risk” groups based on a self-reported rating scale to evaluate their abuse of smartphones. As a result, 36 students were categorized as “high risk” and 59 were categorized as “low risk.” The researchers collected over 50,000 hours of smartphone use encompassing power levels, screen, battery status, application use, internet use, calling, and texting. The results showed that the “high risk” group used only 1~2 applications, focusing on mobile messengers (Kakotalk, etc.) and SNS (Facebook, etc.). In addition, a relationship was found between alarm function and addiction levels. Users who set alarms for Kakaotalk messages and SNS comments used smartphones for an additional 38 minutes per day on average. Results also showed that “high risk” students were on their smartphones for 4 hours and 13 minutes per day, 46 minutes longer than “low risk” students who used smartphones for 3 hours and 27 minutes. The difference was prevalent during 6 am and noon, and 6pm and midnight. In addition, “high risk” students accessed their smartphones 11.4 times more than “low risk” students. Based on the collected data, Professor Lee developed an automatic system that distinguished users into “high risk” or “low risk” categories with 80% accuracy. The new system is expected to give an early diagnosis of addiction to smartphone users, thereby allowing for early treatment and intervention before the user becomes addicted. Professor Lee commented that, "the conventional addiction analysis based on self-analysis surveys did not provide real-time data and were largely inaccurate. The new system overcomes these limitations through data science and personal big data analysis" and that he is "developing an application that monitors smartphone abuse." Figure 1. Usage amount: overall and application-specific results Figure 2. Usage frequency: overall and application-specific results Figure 3. Overall diurnal usage time and frequency
2014.06.05
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Professor Jang Wook Choi Received the Scientist of the Month Award from Daejeon City
Professor Jang Wook Choi of the Graduate School of EEWS (Energy, Environment, Water, and Sustainability), KAIST, received the “Scientist of the Month Award” from the City of Daejeon. Mayor Hong-chul Yeom visited KAIST on May 30, 2014 and presented the award to Professor Choi. Professor Choi has achieved research excellence over a period of time in the field of rechargeable battery, supercapacitor, and materials chemistry. In the picture below: President Steve Kang (left), Professor Jang Wook Choi (middle), and Mayor Hong-chul Yeom (right)
2014.06.05
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Discovery Channel Featured "TransWall" Developed by Professor Woohun Lee
One of the most popular television programs at Discovery Channel in Canada, Daily Planet, a daily science magazine show that delivers a fascinating mix of documentaries and features, aired "TransWall” (http://vimeo.com/70391422) developed by Professor Woohun Lee of Industrial Design at KAIST. TransWall is a two-sided touchable transparent display with a surface transducer incorporated in the display. It enables users to see, hear, or even touch people standing on the other side of the display, thereby enhancing interactive experiences when playing games or communicating. TransWall was introduced at the 2014 ACM (Association for Computing Machinery) Conference on Human Factors in Computing Systems (CHI) held in Toronto, Canada, from April 26 to May 1. The Channel learned about the technology at the conference and produced the show on April 30, 2014. To watch the show, please visit: http://www.youtube.com/watch?v=5GGP59S7T2k&list=PLXmuftxI6pTXuyjjrGFlcN5YFTKZinDhK.
2014.05.29
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Professor Kyu-Young Whang receives the PAKDD Distinguished Contributions Award
Professor Kyu-Young Whag Dr. Kyu-Young Whang, Distinguished Professor from the Department of Computer Science, KAIST, has received the 2014 Distinguished Contributions Award from the Pacific-Asia Conference on Knowledge Discovery and Data Mining (PAKDD). PAKDD is the leading academic international conference on data mining held in Asia/Pacific. This year’s international conference was held from 13th to 15th May at Tainan, Taiwan. As a life member of the PAKDD Steering Committee, Professor Whang worked for the development of the data mining field in the Asia-Pacific region, and his contribution to the international database and data-mining field has been widely recognized. The PAKDD Distinguished Contributions Award has been awarded to a total of six people until now, including Professor Whang, and he is the first Korean to receive this award. Professor Whang has also a history of receiving the Outstanding Contributions Award in 2011 from the Database Systems for Advanced Applications (DASFAA), the prestigious database academic conference in the Asia-Pacific region. The database and data mining field in the region was barren 20 years ago, but through the efforts and contributions of many researchers, including Professor Whang, it has now leapt to the level of being the equal of North American and European researchers. In fact, three academic organizations in the current international database field are led by professors in the Asia-Pacific region. The IEEE ICDE (Institute of Electrical and Electronics Engineers Technical Committee on Data Engineering) is led by Professor Whang; the VLDB (Very Large Data Base) Endowment by Professor Beng Chin Ooi from National University of Singapore (NUS); and the ACM SIGMOD (Association for Computing Machinery Special Interest Group on Management of Data) by Professor Don Kossmann from ETH Zurich.
2014.05.26
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KAIST-Coursera Course: Introduction to Acoustics Engineering
Professor Yang-Hann Kim of Mechanical Engineering at KAIST has been offering an online course entitled “Introduction to Acoustics” on Corsera, the world’s largest MOOCs (Massive Open Online Courses) provider, from May 12th. KAIST offered three Coursera classes during a spring semester in 2014, and Professor Kim’s course was the first one provided by the university to global learners. Professor Kim has immersed himself in research and education on acoustics engineering for the past 30 years. His Coursera class has received positive responses from students, and some important data follows below: For the past ten days, over 6,000 students from all around the world have enrolled the class. The student population consists of 33% in North America (United States and Canada), 32% in Europe, 23% in Asia, 8% in South America, and 2% in Africa. Arranged in order of countries, 25% of access originated from the United States, 8% from India, and 3% or 4% each from Brazil, Britain, Spain, Canada, Germany, Mexico, China, Russia, and France, and 2% from Korea. The other two KAIST-Coursera classes are “Supply Chain Management: A Learning Perspective” and “Introduction to Light, Color, and Life.” For more information, please visit https://www.coursera.org/kaist.
2014.05.25
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KAIST Conducts Safety Awareness Campaign for Research and Experiment
KAIST had an opening ceremony to hold its first “Safety Awareness Campaign for Research and Experiment” on 13th May. Over 100 people attended the ceremony, including President Steve Kang, Provost Gyu-Ho Park, and the Dean of the Administration Office Jae-Nam Lee, as well as the Chief of the Department of Research Environment Safety from the Ministry of Science, ICT and Future Planning, Republic of Korea. On the day of the event, Year 2014 was proclaimed as the first year of accident-free KAIST research and laboratory facilities. A certificate of merit was awarded to promote safe and comfortable research environments. The Department of Civil and Environmental Engineering, KAIST, was selected as the department with the best lab safety management and the Department of Mechanical Engineering as the second. Along with the merit award ceremony, the results of the “7th Research and Laboratory Safety Campaign Contest” were announced: “Lady First When Dating, Safety First When Experimenting!” written by Jong-Su Bae from the Department of Mechanical Engineering was selected as the best slogan, and Hyeon-Chae Noh from the Department of Civil and Environmental Engineering received the award for best poster. President Steve Kang said, “KAIST is constantly striving to establish a comprehensive safety management system and to promote a safe research and laboratory environment,” and “To ensure the safety of KAIST and its members, we will be as supportive as possible.” Below is the winner of the poster from the 7th Research and Laboratory Safety Campaign Contest. What Would You Rather Wear? Gloves or Bandages? Gloves worn in laboratories are protection from hazardous materials that students and researchers may come in contact with. The poster emphasizes the importance of wearing protective gloves when conducting research or experiment.
2014.05.19
View 8537
Immune Evasion Mechanism of Hepatitis C Virus Revealed
Professor Ui-Cheol Shin Inhibiting major histocompatibility complex [MHC] class I protein expression, T cell immune response is evaded. The research will be a great help to the development of C hepatitis vaccine. Roughly 1-2% of the population in Korea is known to be infected with Hepatitis C. Most Hepatitis C Virus (HCV) infections progress to a chronic disease and can cause liver cirrhosis or liver cancer, which may lead to death. Unlike Hepatitis type A or B, there is no vaccine for Hepatitis C Virus and therefore avoiding exposure to the virus is the best known method of prevention. However, a team of researchers at KAIST has produced research results, which may contribute significantly to the vaccine development. KAIST Graduate School of Medical Sciences & Engineering’ Professor Ui-Cheol Shin and his team have successfully identified why Hepatitis C Virus does not cause an immune response within the human body. The research results were published in the May edition of The Journal of Gastroenterology, a world-renowned journal in the field of gastroenterology. The immune response occurs to eliminate the virus that has invaded our body. During this process, a major histocompatibility complex [MHC] class I plays a key role in inducing T cell response, which is needed for the elimination of virus-infected cells. When a cell is infected by a virus, a substance called interferon causes the increased expression of major histocompatibility complex class I. T cell recognizes the increased MHC class I and therefore finds the virus-infected cells. However, the effect that Hepatitis C Virus has on major histocompatibility complex class I has not been clearly identified until now. The research team has revealed, using a cell culture for infection systems, that the Hepatitis C Virus suppresses the expression of major histocompatibility complex class I. Also, the mechanism to prove that HCV activates a protein called PKR within the cell to inhibit MHC class I protein expression was identified at a molecular level. In this study, researchers established the hypothesis that regulating PKR protein in the cell can enhance the T cell immune response, which was then proved through experiments. Professor Ui-Cheol Shin said, “There are a lot of new drugs to treat Hepatitis C Virus, while its vaccine has not been developed yet. Revealing the HCV immune evasion mechanism will help stimulate momentum for the HCV vaccine development.” The first author of the journal, Dr. Won-Seok Kang is a graduate from Yonsei College of Medicine. After earning his medical degree, he has continued his training as a ‘doctor-scientist’ at KAIST Graduate School of Medical Sciences & Engineering to study Hepatitis C Virus immune evasion mechanism in this research. Hepatitis C Virus activates PKR-eIF2a pathway, which inhibits the major histocompatibility complex class I, and therefore weakens the T cell activation to the viral activity.
2014.05.19
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KAIST Made Great Improvements of Nanogenerator Power Efficiency
The energy efficiency of a piezoelectric nanogenerator developed by KAIST has increased by almost 40 times, one step closer toward the commercialization of flexible energy harvesters that can supply power infinitely to wearable, implantable electronic devices. NANOGENERATORS are innovative self-powered energy harvesters that convert kinetic energy created from vibrational and mechanical sources into electrical power, removing the need of external circuits or batteries for electronic devices. This innovation is vital in realizing sustainable energy generation in isolated, inaccessible, or indoor environments and even in the human body. Nanogenerators, a flexible and lightweight energy harvester on a plastic substrate, can scavenge energy from the extremely tiny movements of natural resources and human body such as wind, water flow, heartbeats, and diaphragm and respiration activities to generate electrical signals. The generators are not only self-powered, flexible devices but also can provide permanent power sources to implantable biomedical devices, including cardiac pacemakers and deep brain stimulators. However, poor energy efficiency and a complex fabrication process have posed challenges to the commercialization of nanogenerators. Keon Jae Lee, Associate Professor of Materials Science and Engineering at KAIST, and his colleagues have recently proposed a solution by developing a robust technique to transfer a high-quality piezoelectric thin film from bulk sapphire substrates to plastic substrates using laser lift-off (LLO). Applying the inorganic-based laser lift-off (LLO) process, the research team produced a large-area PZT thin film nanogenerators on flexible substrates (2cm x 2cm). “We were able to convert a high-output performance of ~250 V from the slight mechanical deformation of a single thin plastic substrate. Such output power is just enough to turn on 100 LED lights,” Keon Jae Lee explained. The self-powered nanogenerators can also work with finger and foot motions. For example, under the irregular and slight bending motions of a human finger, the measured current signals had a high electric power of ~8.7 μA. In addition, the piezoelectric nanogenerator has world-record power conversion efficiency, almost 40 times higher than previously reported similar research results, solving the drawbacks related to the fabrication complexity and low energy efficiency. Lee further commented, “Building on this concept, it is highly expected that tiny mechanical motions, including human body movements of muscle contraction and relaxation, can be readily converted into electrical energy and, furthermore, acted as eternal power sources.” The research team is currently studying a method to build three-dimensional stacking of flexible piezoelectric thin films to enhance output power, as well as conducting a clinical experiment with a flexible nanogenerator. This research result, entitled “Highly-efficient, Flexible Piezoelectric PZT Thin Film Nanogenerator on Plastic Substrates,” was published as the cover article of the April issue of Advanced Materials. (http://onlinelibrary.wiley.com/doi/10.1002/adma.201305659/abstract) YouTube Link: http://www.youtube.com/watch?v=G_Fny7Xb9ig Over 100 LEDs operated by self-powered flexible piezoelectric thin film nanogenerator Flexible PZT thin film nanogenerator using inorganic-based laser lift-off process Photograph of large-area PZT thin film nanogenerator (3.5cm × 3.5cm) on a curved glass tube and 105 commercial LEDs operated by self-powered flexible piezoelectric energy harvester
2014.05.19
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