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New BioFactory Technique Developed using sRNAs
Professor Sang Yup Lee - published on the online edition of Nature Biotechnology. “Expected as a new strategy for the bio industry that may replace the chemical industry.”- KAIST Chemical & Biomolecular engineering department’s Professor Sang Yup Lee and his team has developed a new technology that utilizes the synthetic small regulatory RNAs (sRNAs) to implement the BioFactory in a larger scale with more effectiveness. * BioFactory: Microbial-based production system which creates the desired compound in mass by manipulating the genes of the cell. In order to solve the problems of modern society, such as environmental pollution caused by the exhaustion of fossil fuels and usage of petrochemical products, an eco-friendly and sustainable bio industry is on the rise. BioFactory development technology has especially attracted the attention world-wide, with its ability to produce bio-energy, pharmaceuticals, eco-friendly materials and more. For the development of an excellent BioFactory, selection for the gene that produces the desired compounds must be accompanied by finding the microorganism with high production efficiency; however, the previous research method had a complicated and time-consuming problem of having to manipulate the genes of the microorganism one by one. Professor Sang Yup Lee’s research team, including Dr. Dokyun Na and Dr. Seung Min Yoo, has produced the synthetic sRNAs and utilized it to overcome the technical limitations mentioned above. In particular, unlike the existing method, this technology using synthetic sRNAs exhibits no strain specificity which can dramatically shorten the experiment that used to take months to just a few days. The research team applied the synthetic small regulatory RNA technology to the production of the tyrosine*, which is used as the precursor of the medicinal compound, and cadaverine**, widely utilized in a variety of petrochemical products, and has succeeded developing BioFactory with the world’s highest yield rate (21.9g /L, 12.6g / L each). *tyrosine: amino acid known to control stress and improve concentration **cadaverine: base material used in many petrochemical products, such as polyurethane Professor Sang Yup Lee highlighted the significance of this research: “it is expected the synthetic small regulatory RNA technology will stimulate the BioFactory development and also serve as a catalyst which can make the chemical industry, currently represented by its petroleum energy, transform into bio industry.” The study was carried out with the support of Global Frontier Project (Intelligent Bio-Systems Design and Synthesis Research Unit (Chief Seon Chang Kim)) and the findings have been published on January 20th in the online edition of the worldwide journal Nature Biotechnology.
2013.02.21
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Professor Shin In Shik First in Asia to receive Excellent Dissertation Award from IEEE RTSS
The research team lead by Professor Shin In Shik (Department of Computer Science) received the Excellent Dissertation Awardy in the IEEE RTSS out of 157 dissertations. It is the first time a Professor under an institute in the Asia region received the Award in the RTSS field during its 33 year history. Professor Shin had already received an Excellent Dissertation Award as a Ph.D. candidate at the University of Pennsylvania. Thus Professor Shin became the first and only scientist to receive the Award twice. Professor Shin has successfully defined the scheduling method of the multicore processor which was regarded as the problem in the field of RTSS for the past decade. Professor Shin has suggested new criteria for sorting real time tasks in parallel thereby suggesting a new scheduling method that surpasses current scheduling methods. The results are anticipated to provide new perspectives in the field of RTSS using multicore processors.
2013.01.22
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Professor Lee Jeong Yong Receives 2012 'KAISTian of the Year' Award
Professor Lee Jeong Yong (Department of Material Science and Engineering) received the 2012 ‘KAISTian of the Year’ Award. Professor Lee had successfully developed a technique that allowed the observation and analysis of liquid in atomic scale. The technique is expected to have great impact on nano-material synthesis in solution, explaining electrode and electrolyte reaction, liquid and catalysis reaction research, and etc. and was therefore named as the best experimental accomplishment in KAIST in 2012. Professor Lee and his team’s finding has been published in the April edition of Science magazine and has had attracted the attention of the world. In addition, BBC News, and Science & Environment reported on the findings as their respective top articles. The optical microscope is incapable of atomic scale observation and the electron microscopes are capable but because of the vacuum state all liquids undergo evaporation making it impossible to observe liquids in an atomic scale. Professor Lee’s team wrapped the liquid with a layer of grapheme to prevent evaporation and successfully observed real time the platinum growth process in solution. Professor Lee’s findings were introduced as an example of exemplar research case in the Presidential address for ‘Science Day’ in April.
2013.01.22
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Professor Hwang Kyu Young and Professor Yang Dong Yeol Receives Engineer of Korea Award
Emeritus Professor Hwang Kyu Young (Department of Computer Sciences) and Professor Yang Dong Yeol (Department of Mechanical Engineering) were named as the 2012 Engineer of Korea by the Ministry of Education, Science, and Technology and Korea Science Foundation. The Engineer of Korea Award is awarded biannually to scientists and engineers that have contributed to the development of Korea’s science and technology and national economy. Professor Hwang’s work with DBMS and close coupling architecture of information search and overall new theories and application technology development in the field of database system has aided the opening and expansion of IT software industry development and the advent of internet information culture era. Professor Yang is a word renowned scholar in the field of net shape manufacturing and is considered to have opened a new page in the field of nano-molding technique. In addition, Professor Eum Sang Il (Department of Mathematical Science) has been selected as the 2012 Young Scientist Award.
2013.01.22
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KAIST Professors win 2012 Korea Engineering Award
Distinguished Professor Hwang Gyu Young (Department of Computer Science) and Professor Yang Dong Yol (Department of Mechanical Engineering) from KAIST received the 2012 ‘Korea Engineering Award’ hosted by the Ministry of Education, Science and Technology and the Korea Research Foundation. The ‘Korea Engineering Award’ is given biennially to researchers who have accomplished world class research and have contributed greatly to Korea’s development in the field of Science and Technology. The award started in 1994 and a total of 24 recipients were recognized in various fields such as electronics, mechanics, chemistry, construction, etc. The recipients of the award areawarded the Presidential award as well as 50million won as prize money. Professor Hwang was recognized for his research on DBMS close-coupling architecture as well as other new data base system theories, contributing to the development of the IT software industry in Korea. Professor Yang was praised for his work in precision shape creation and manufacturing, especially for his work in the nano-stereolithography process. In addition, Professor Oum Sang-il from the Deparment of Mathematical Science received the 2012 ‘Young Scientist Award’ hosted by the Ministry of Education, Science and Technology and the Korean Academy of Science and Technology. The ceremony for ‘Korea Engineering Award’ and the ‘Young Scientist Award’ was held in Seoul Press Center Press Club on the 21st of December.
2012.12.26
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Professor Cho Young-ho wins 'E2 Star' award
Professor Cho Young-ho from the Department of Bio and Brain Engineering at KAIST was chosen as the ‘E2 Star’ at the ‘2012 Engineering Education Festa’ in academics. The ‘2012 Engineering Education Festa’ hosted by the Ministry of Education, Science and Technology was held to display outstanding research results and to conceptualize the future of science education. The ‘E2 star’ award is given to renowned figures in industry, academia and society. A total of 35 candidates were recommended for the 3 fields and Professor Cho received the first place in the online voting. Professor Cho received high marks for his work in engineering education, research development and increasing the communication between academia and industry, as well as the commercialization of science and technology. Professor Cho was especially praised for the specialization of engineering education in integrated fields and the joint research with US and Swiss universities. Professor Cho Young-ho(Department of Bio and Brain Engineering, KAIST)
2012.12.26
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Professor Hwang Gyu Young Elected as Chairman of IEEE TCDE.
Professor Hwang Gyu Young (Department of Computer Science) was elected as the Chairman of IEEE (Institute of Electrical and Electronics Engineers) TCDE (Technical Committee on Data Engineering). IEEE TCDE is one of the three academic organizations (including VLDB Endowment, ACM SIGMOD) and Professor Hwang is the first to be elected as Chairman from the Asia-Pacific region. Professor Hwang’s tenure begins on New Year’s Day for two years. IEEE TCDE holds the world’s most prestigious academic competition IEEE ICDE and hosts the Working Group and publishes the IEEE Data Engineering Bulletin.
2012.12.21
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KAIST shocks the world with its creativity
Researchers at KAIST yielded great results at the world’s leading international Human Computer Interaction Society. Professor Lee Gi Hyuk’s (Department of Computer Sciences) and Professor Bae Seok Hyung’ (Department of Industrial Design) respective teams received awards in two criteria in student innovation contest and was the only domestic university that presented their thesis at the ACM Symposium on User Interface Software. The ACM UIST holds a student innovation contest prior to its opening. This year’s topic was the pressure sensing multi touch pad of Synaptics and involved 27 prestigious universities including MIT and CMU. The KAIST team (Ki Son Joon Ph.D. candidate, Son Jeong Min M.A. candidate of Department of Computer Sciences and Woo Soo Jin M.A. candidate of Department of Industrial Design) designed a system that allows modulated control by attaching a simple structure to the pressure sensing multi touch pad. The second KAIST team (Huh Seong Guk Ph.D. candidate, Han Jae Hyun Ph.D. candidate, Koo Ji Sung Ph.D. candidate at the Department of Computer Sciences, and Choi Ha Yan M.A. candidate at Department of Industrial Design) designed a system that utilizes a highly elastic fiber to allow the sensing of lateral forces. They also created a slingshot game application which was the second most popular system. In the thesis session Professor Bae’s team (Lee DaWhee Ph.D. candidate, Son Kyung Hee Ph.D. candidate, Lee Joon Hyup M.A. candidate at Department of Industrial Design) presented a thesis that dealt with the technology that innovated the table pen for displays. The new ‘phantom pen’ solved the issue arising from the hiding effect of the pen’s contact point and the display error due to the thickness of the display. In addition the ‘phantom pen’ has the ability to show the same effects as crayons or markers in a digital environment.
2012.11.29
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Distinguished Professor Lee Sang Yeop Appointed as Fellow of the American Institute of Chemical Engineers
Professor Lee Sang Yeop (Dean of the Department of Biological Sciences) has become the first Korea Scientist to be appointed as the Fellow of the American Institute of Chemical Engineers. The American Institute of Chemical Engineers was founded in 1908 and boasts a 100 year history. It is composed of 43,000 members over 90 countries and is the largest international Academic Institute in the field of Chemical Engineering. The Institute appoints Fellows after a rigorous procedure of recommendation and evaluation and Professor Lee is the first Korean to become a Fellow. Professor Lee’s expertise is the field of Metabolic Engineering and successfully applied the system design method and optimization strategy of chemical engineering to biological systems thereby developing numerous core technologies for the biology based chemical industries. Professor Lee is the founder of the System Metabolic Engineering and enabled the medical application of microorganisms by manipulating the metabolic pathways on a systems level in addition to making great progress in synthesizing various oil originated chemical materials using biology based, environmentally friends methods. Professor Lee received the Marvin J. Johnson Award, Charles Thom Award, and has been appointed by the first Chairman of the Biotech Global Agenda Counsel of the World Economic Forum.
2012.09.22
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Professor Soon-Heung Chang meets with Bill Gates and discusses possible collaboration
Professor Soon-Heung Chang from the Department of Nuclear and Quantum Engineering, KAIST, who is also the president of Korea Nuclear Society (KNS), met Bill Gates, the co-founder and former chief executive officer (CEO) of Microsoft, on August 16, 2012 and discussed ways to cooperate for the development of a sodium-cooled fast reactor (SFR), a next generation nuclear power reactor. According to Professor Chang, Bill Gates was amazed at Korea’s successful bids for nuclear power plants in the United Arab Emirates, even though Korea was a latecomer in the field of nuclear power. Bill Gates also showed a keen interest in Korea’s low electricity rates. Gates focuses on solving fundamental problems in order to help improve the quality of life for humanity, rather than short-term temporary solutions, through infrastructure development such as energy. Particularly, he considers nuclear power as one of the most effective ways to supply clean energy which can provide electricity at a low cost while keeping carbon dioxide emission levels much lower than fossil fuels. Bill Gates is a primary investor for an energy company called “TerraPower” based in Bellevue, Washington. TerraPower develops and commercializes nuclear power technology for a traveling wave reactor (TWR) that is designed to use spent fuels, i.e., depleted uranium, and runs technically “forever” because once fueled, the reactor does not need to be refueled for over 50 years. TerraPower’s TWR is to use metallic fuel, and Korea is the only country that currently develops SFR (KALIMER 600) using metallic fuel. “Korea has an outstanding supply chain for the entire lifecycle of a nuclear power station from equipment manufacturing to operation,” said Professor Chang, while emphasizing the synergistic effects of forming partnership between Korea and TerraPower. Professor Chang emphasized that Korea should create an opportunity based on lessons learned from the Fukushima crisis and actively move forward to achieve its leading position in the field of next generation nuclear reactors. He said that cooperation with Bill Gates will be a significant step towards the development of next generation nuclear reactors. About Sodium-cooled Fast Reactor (SFR) Sodium-cooled Fast Reactor (SFR) is a next-generation nuclear power reactor that will use spent fuels from conventional reactors. Arrangement of a fuel recycling system in conjunction with currently-developing pyroprocessing technology would enable U-238, which makes up over 99% of natural uranium, to be used as a nuclear fuel. This would greatly reduce the toxicity and volume of spent fuels by up to 1,000 times and 100 times respectively when compared to existing reactors. This is truly a breakthrough innovation in spent fuel disposal and recycling.
2012.09.20
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Professor Song Joon Hwa develops new Location Tracking Application
Professor Song Joon Hwa developed a location tracking application that alerts the teacher when students on field trips stray too far from the group via a smartphone and a headset. Conventional Location Tracking Applications utilize GPS systems and as a consequence does not function indoors where the satellite signal is nonexistent. However Professor Song’s method is unique in the fact that it utilizes radio waves which allows signal transfer both indoors and outdoors. In addition different alerts are given off in difference locations and therefore the technology can be applied in finding the effectiveness of the field trip and the social behaviors of students.
2012.09.11
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Professor Kyung Wook Baek Wins the Best Thesis Award at the 2012 Pan-Pacific Microelectronic Symposium
Prof. Kyung Wook Baek from KAIST"s material science department has won the Best Thesis Award at the 2012 Pan-Pacific Microelectronic Symposium. The title of this thesis was "Recent Advances in Anisotropic Conductive Adhesives Technology : Materials and Processes". Prof Baek had the honor of having his thesis be appointed the best thesis of the symposium. This thesis includes his 15 years of research on ACAs which are a key element of display and semiconductor packaging technology. Prof. Baek"s research results has been recognized as incredibly innovative in the field of ACAs and ultrasonic connection devices. This thesis has been recognized as setting the foundation for commercialization by professionals from all over the world at the symposium. Prof. Baek has announced two innovative technologies on ACAs at the symposium. One is a technology that merges the nanofiber technology with the ATAs. This technology was highly applauded for overcoming the problem of electric connection in micro-pitch display semiconductors, and successfully applying this to electronic packaging materials. Currently, commercialization process based on the patent is ongoing. It is expected that we will be able to take hold of the entire market once the commercialization succeeds. The other technology was to improve the liability and overcome the limits of the current flow in ACAs through the use of solder molecules. This is also undergoing commercialization process for use in mobile electronic devices. Together with this, Prof.Baek has reported an innovative case where the original heat compression process was replaced with a new ultrasonic process. This discovery is deemed to be extremely great due to its implications in replacing all heat compression systems. This too will soon be commercialized Prof.Baek has played a crucial role in the development of electronic packaging material and processing technology. He has written the largest number of theses in this area, and has proven himself to be the world"s best through winning this award.
2012.05.10
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