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Professor Lee's Research Selected as Top 100 National R&D Projects
A research project, led by Research Professor Ju Yong Lee from the KAIST Institute for IT Convergence, was selected as one of the Top 100 National Research and Development Projects 2017. This research project, titled LTE-A-based Single RF Small Base Station supporting Multiple Streams, developed 300Mbps low power, low complexity and broadband small base station technology that supports 4x4 MIMO (Multiple Input and Multiple Output) by proposing a new antenna structure and a new RF (Radio Frequency) structure based on LTE-A. Professors from the School of Electrical Engineering at KAIST, Dong Ho Cho, Songcheol Hong, and Yong Hoon Lee also collaborated on the project. The existing heterodyne method of communication systems generates the problems of increasing unit price and system complexity. In this project, however, Professor Lee directly modulated the baseband signal from the RF stage through an impedance loading-based RF chip. This method was designed to facilitate low power as well as low complexity while supporting broadband service. Based on this, his team developed source technology for RF that can be applied to fourth and even fifth generation networks. Furthermore, this base station is smallest among the small-cell stations so far, providing an eco-friendly installation environment. It contributes to the market for fifth generation mobile communications by reducing power consumption significantly yet providing high-capacity services. Professor Lee said, “This technology will contribute to creating a new market and additional jobs because business based on the fifth mobile generation can provide multi-functional services, including multiband. Requiring low power and providing high-capacity services anywhere at any time will enhance national competence and reduce costs for establishing a next generation mobile communication system. It is expected that this technology will help with disseminating mobile communication infrastructure through expanding information and communication system as well as the infrastructure of island areas.”
2017.11.08
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KAST Opened the Campus to the Public
KAIST hosted OPEN KAIST 2017 on the main campus from November 2 to 3, 2017. OPEN KAIST is a science and cultural event designed for students and the general public to experience and take a glance at research labs. More than 10,000 visitors came to KAIST this year. Groups of families and students came to KAIST to experience various programs related to science. Twenty departments, including Mechanical Engineering, Aerospace Engineering, the Graduate School of Cultural Technology, and Materials Science and Engineering participated in the event, along with three research centers and the Public Relations Office. The event was composed of a total of 70 programs in four sections: lab tour, research performance exhibition, department introduction, and special lectures. The kick off activity for the event was a trial game of the AI World Cup 2017 which will be hosted by KAIST in December 2017. Many people also visited the mobile health care showroom where they could experience what a future smart home and hospital would look like. It was also interesting to visit a futuristic living space for one-person households that provides virtual reality services. KAIST hopes that the event offers an opportunity for children and students to get to know about science better. Professor Jong-Hwan Kim, the Dean of the College of Engineering at KAIST said, “OPEN KAIST is the one and only opportunity to visit and experience our research labs. KAIST will make every effort to take a step closer to the public by focusing on research that contributes to human society.”
2017.11.06
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College of Business Honored with the WRDS-SSNR Innovation Award
(Professor Inmoo Lee (far left), Robert Zarazowski (WRDS), Gregg Gordon (SSRN) and Professor Jae Kyu Lee) The KAIST College of Business received the WRDS (Wharton Research Data Services)-SSNR Innovation Award for the Asia-Pacific region on October 31 during the AACSB Asia-Pacific Conference in Seoul. The WRDS-SSRN Innovation Award is intended to elevate the visibility of pioneering research across a broad range of financial and economic topics. Three winners are selected annually from across North America, Europe, and the Asia Pacific based on their ability to demonstrate innovation and research excellence. The award was created through collaboration with SSRN, the world’s leading early-stage research platform and Elsevier, a global information analytics company specializing in science and health. It honors top business schools that produce exceptional data-driven research. A part of the Wharton School of the University of Pennsylvania, WRDS provides global corporations, universities, and regulatory agencies with the thought leadership, data access, and analytics needed to enable impactful research. The Dean of the College of Business Youngbae Kim, said that KAIST has been taking the lead in responding to global trends, offering many innovative programs such as an MBA for Social Entrepreneurship and the Master Course for Green Growth Management. KAIST already has been selected as the Most Innovative University in the Asia-Pacific Region by Thomson Reuters for the last two years. Robert Zarazowski, managing director of WRDS said they recognize and support the outstanding achievement taking place at KAIST as well as its commitment to growth and innovation in business education.
2017.11.03
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Scientist of November, Professor Hyung Jin Sung
Professor Hyung Jin Sung from the Department of Mechanical Engineering at KAIST received a ‘Science and Technology Award of the Month’ given by the Ministry of ICT and Science and the National Research Foundation of Korea for November 2017. He developed technology that can exquisitely control a micrometer-scaled liquid drop on a dime-sized lab-on-a-chip. With his work, he was recognized for reinforcing research capability on microfluidics. Lab-on-a-chip is an emerging experiment and diagnostic technology in the form of a bio-microchip that facilitates complex and various experiments with only a minimal sample size required. This technology draws a lot of attention not only from medical and pharmaceutical areas, but also the health and environmental field. The biggest problem was that technology for the temperature control of a fluid sample, which is one of the core technologies in microfluidics, has low accuracy. This limit had to be overcome in order to use the lab-on-a-chip more widely. Professor Sung developed an acoustic and thermal method which controls the temperature of a droplet quickly and meticulously by using sound and energy. This is a thermal method that uses heat generated during the absorption of an acoustic wave into viscoelastic substances. It facilitates a rapid heating rate and spatial-temporal temperature control, allowing heating in desired areas. In addition, Professor Sung applied his technology to polymerase chain reactions, which are used to amplify DNA. Through this experiment, he successfully shortened the reaction time from 1-2 hours to only three minutes, making this a groundbreaking achievement. Professor Sung said, “My research is significant for enhancing the applicability of microfluidics. I expect that it will lead to technological innovations in healthcare fields including biochemistry, medical checkups, and new medicine development.”
2017.11.03
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In Jin Cho Earned the Best Poster Prize at ME Summit 2017
In Jin Cho, a Ph.D. student in the Department of Chemical and Biomolecular Engineering at KAIST received the best poster prize at the International Metabolic Engineering Summit 2017 held on October 24 in Beijing, China. The International Metabolic Engineering Summit is a global conference where scientists and corporate researchers in the field of metabolic engineering present their latest research outcomes and build networks. At this year’s summit, about 500 researchers from around the world participated in active academic exchanges, including giving keynote speeches and presenting posters. During the poster session, the summit selects one person for the KeAi-synthetic and Systems Biotechnology Poster Award, two for Microbial Cell Factories Poster Awards, and three for Biotechnology Journal Poster Awards among the posters presented by graduate students, post-doctoral fellows and researchers. Cho received the KeAi-synthetic and Systems Biotechnology Poster Award. Her winning poster is on the biotransformation of p-xylene to terephthalic acid using engineered Escherichia coli. Terephthalic acid is generally produced by p-xylene oxidation; however, this process requires a high temperature and pressure as well as a toxic catalyst during the reaction process. Cho and Ziwei Luo, a Ph.D. student at KAIST, co-conducted the research and developed a successful biological conversion process. Compared to the existing chemical process, it does not require a high temperature and pressure; and it is environmentally friendly with a relatively high conversion rate of approximately 97%. Cho’s advisor, Distinguished Professor Sang Yup Lee said, “Further research on glucose-derived terephthalic acid will enable us to produce biomass-based eco-friendly terephthalic acid through engineered Escherichia coli.”
2017.10.31
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KAIST and KOICA Invited Dominican Republic Officials for Workshop
KAIST will host a two-week workshop for Dominican Republic officials and scholars in collaboration with KOICA (Korea International Cooperation Agency) beginning October 23 at KAIST. The workshop aims to encourage academia-industry cooperation as one of the Projects for Human Resource Development for Science and Technology at KOICA. Dominican participants including the assistant minister of the Ministry of Higher Education, Science and Technology (MESCYT) and deans of engineering colleges at major universities will enjoy lectures from experts and visit enterprises known for excellent academia-industry collaboration. According to the Center for Overseas Development, at which Professor WonJoon Kim in the School of Business and Technology Management at KAIST holds the position of director, the workshop is designed to develop human resources in the science and technology (S&T) area, share knowledge on research and development in the field of academia-industry cooperation, and help the participants acquire know-how for managing partnerships between related organizations and industries. During the workshop, KAIST plans to transfer know-how and share knowledge on its academia-industry cooperation R&D system, in hopes that the workshop will help the Dominican Republic foster its manpower in higher education. The workshop organizers hope that the officers and scholars will be able to apply what they will learn for establishing and carrying out detailed action plans for academia-industry cooperation policies in an effective manner. “This workshop provides an opportunity to learn about the development of S&T in Korea, academia-industry cooperation R&D, and fostering manpower in advanced S&T. Through the knowledge sharing, we can have a better understanding of academia-industry cooperation as well as education on advanced manpower,” said Pedro Antonio Eduardo, the assistant minister of MESCYT. He added, “I hope that this workshop will further detailed cooperation between the two countries for Korean high-tech enterprises’ overseas expansion and advanced manpower education. The development model in Korea has many essential elements, so learning its engine for growth and polytechnic manpower education will help develop my country’s industry sector.” The Project for Human Resource Development for Science and Technology is one of the official development assistance projects running from last year until 2019. It promotes R&D activities for S&T in the Dominican Republic, encouraging academia-industry cooperation by improving trainers in charge of advanced manpower education.
2017.10.30
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Distinguished Professor Lee Named International Fellow of the CAS
Distinguished Professor Sang Yup Lee from the Department of Chemical and Biomolecular Engineering at KAIST was awarded the title of distinguished professor and international fellow from the Chinese Academy of Sciences (CAS), and honorary professor from its affiliated organization the Tianjin Institute of Industrial Biotechnology (TIB). The CAS recognized Distinguished Professor Lee for his significant contributions to biotechnology. He has made significant pioneering academic achievements in the area of systems metabolic engineering, which produces useful chemicals from microorganisms. Not only did he develop the first and best source technology in that field, but also came out with processes for the production of biofuel and environmentally-friendly chemicals.” As a global leader in systems metabolic engineering, Distinguished Professor Lee has also been appointed as an honorary professor at Jiangnan University in Wuxi, China. Distinguished Professor Lee was listed in the ‘Top 20 Translational Researchers of 2014’ selected by the renowned international journal Nature Biotechnology. Moreover, he was the first Asian recipient of the James E. Bailey Award in 2016 and Marvin J. Johnson Award in 2012, which are given to scholars in the field of biotechnology. He is also one of 13 global scientists who are foreign members of the renowned academic societies the National Academy of Engineering and the National Academy of Sciences in the US. Furthermore, he received the ‘2017 Korea Best Scientist Award’ from the president of Korea in July. Finally, his founding field, systems metabolic engineering, was chosen as one of the ‘Top 10 Emerging Technologies of 2016’ by the World Economic Forum. The Chinese Academy of Sciences, established in November 1949, is an academic organization that carries out research on basic sciences and natural sciences in China. It defined its science and technology system to include the fields of basic sciences, natural sciences, and high technology. While having a base in Beijing, its branch academies are located in 12 main cities along with 117 affiliates and 100 national key labs.
2017.10.26
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Development of a Highly-Accurate Computational Model of Human Metabolism
A research team from KAIST developed a computational framework that enables the reconstruction of a comprehensive computational model of human metabolism, which allows for an accurate prediction of personal metabolic features (or phenotypes). Understanding personal metabolic phenotypes allows us to design effective therapeutic strategies for various chronic and infectious diseases. A human computational model called the genome-scale metabolic model (GEM) contains information on thousands of metabolic genes and their corresponding reactions and metabolites, and has played an important role in predicting metabolic phenotypes. Although several versions of human GEMs have been released, they had room for further development, especially as to incorporating biological information coming from a human genetics mechanism called “alternative splicing.” Alternative splicing is a genetic mechanism that allows a gene to give rise to multiple reactions, and is strongly associated with pathology. To tackle this problem, Jae Yong Ryu (a Ph.D. student), Dr. Hyun Uk Kim (Research Fellow), and Distinguished Professor Sang Yup Lee, all from the Department of Chemical and Biomolecular Engineering at KAIST, developed a computational framework that systematically generates metabolic reactions, and adds them to the human GEM. The resulting human GEM was demonstrated to accurately predict metabolic phenotypes under varied environmental conditions. The research results were published online in Proceedings of the National Academy of Sciences (PNAS) on October 24, 2017, under the title “Framework and resource for more than 11,000 gene-transcript-protein-reaction associations in human metabolism.” The research team first updated the biological contents of a previous version of the human GEM. The updated biological contents include metabolic genes and their corresponding metabolites and reactions. In particular, metabolic reactions catalyzed by already-known protein isoforms were additionally incorporated into the human GEM; protein isoforms are multiple variants of proteins generated from individual genes through the alternative splicing process. Each protein isoform is often responsible for the operation of a metabolic reaction. Although multiple protein isoforms generated from one gene can play different functions by having different sets of protein domains and/or subcellular localizations, such information was not properly considered in previous versions of human GEMs. Upon the initial update of the human GEM, named Recon 2M.1, the research team subsequently implemented a computational framework that systematically generates information on Gene-Transcript-Protein-Reaction Associations (GeTPRA) in order to identify protein isoforms that were previously not identified. This framework was developed in this study. As a result of the implementation of the framework for GeTPRA, more than 11,000 GeTPRA were automatically predicted, and thoroughly validated. Additional metabolic reactions were then added to Recon 2M.1 based on the predicted GeTPRA for the previously uncharacterized protein isoforms; Recon 2M.1 was renamed Recon 2M.2 from this upgrade. Finally, Recon 2M.2 was integrated with 446 sets of personal biological data (RNA-Seq data) in order to build patient-specific cancer models. These patient-specific cancer models were used to predict cancer metabolism activities and anticancer targets. The development of a new version of human GEMs along with the computational framework for GeTPRA is expected to boost studies in fundamental human genetics and medicine. Model files of the human GEMs Recon 2M.1 and 2M.2, a full list of the GeTPRA and the source code for the computational framework to predict the GeTPRA are all available as part of the publication of this study. Distinguished Professor Lee said, “The predicted GeTPRA from the computational framework is expected to serve as a guideline for future experiments on human genetics and biochemistry, whereas the resulting Recon 2M.2 can be used to predict drug targets for various human diseases.” This work was supported by the Technology Development Program to Solve Climate Changes on Systems Metabolic Engineering for Biorefineries (NRF-2012M1A2A2026556 and NRF-2012M1A2A2026557) from the Ministry of Science and ICT through the National Research Foundation (NRF) of Korea. (Figure 1:A scheme of Recon 2M.1 development and its use in reconstructing personal genome-scale metabolic models (GEMs). (A) A concept of alternative splicing of human genes and its use in Gene-Transcript-Protein-Reaction Associations (GeTPRA) of Recon 2M.1. (B) A procedure of systematic refinement of the Recon 2Q. Recon 2Q is one of the previously released human GEMs. Biochemically inconsistent reactions include unbalanced, artificial, blocked, and/or redundant reactions. Iterative manual curation was conducted while validating the Recon 2M.1. (C) Reconstruction of cancer patient-specific GEMs using Recon 2M.1 for further simulation studies. In this study, personal biological data (RNA-Seq data) were obtained from The Cancer Genome Atlas (TCGA; https://cancergenome.nih.gov/ ) across the ten cancer types. (Figure 2: Computational framework for the systematic generation of Gene-Transcript-Protein-Reaction Associations (GeTPRA; red box in the flowchart). Peptide sequences of metabolic genes defined in Recon 2M.1 were retrieved from a database called Ensembl. EC numbers and subcellular localizations of all the protein isoforms of metabolic genes in Recon 2M.1 were predicted using software programs EFICAz2.5 and Wolf PSort, respectively. Information on the newly predicted GeTPRA was systematically incorporated into the Recon 2M.1, thereby resulting in Recon 2M.2.)
2017.10.25
View 8709
Professor Dai Gil Lee Recognized by the ICCS
Emeritus Professor Dai Gil Lee, from the School of Mechanical and Aerospace Engineering at KAIST, received a special achievement award from the 20th International Conference on Composite Structures (ICCS). ICCS is a renowned conference in the field of applied composite structures, which highlights the practicality of composite structures. This year, the conference was held at the Conservatoire National des Arts et Métiers (CNAM), Paris, France from September 4 to 7. Approximately 650 papers were presented from 45 countries. Especially, the conference honored Emeritus Professor Lee, who has been engaged in ICCS since 1993 and received best paper award twice. The ICCS recognized him for serving with distinction in science and technology in the fields of composite materials and structures. As a member of the Editorial Board for many years, he gave significant support to the journal Composite Structures. At the conference, he gave a special lecture titled ‘Lightweight Carbon Composite Proton Exchange Membrane Fuel Cells’. Professor Lee said, “I will dedicate myself to innovate Vanadium Redox Flow Battery-ESS (VRFB) based on the research findings announced at the conference and related patents. I am hoping that these efforts will contribute to solving energy issues around the world.”
2017.10.19
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KAIST Partners with WEF to Prepare for the 4th Industrial Revolution
KAIST President Sung-Chul Shin and the Head of the World Economic Forum Center for the Fourth Industrial Revolution, Murat Sonmez, made a commitment to build cooperation in an active manner for addressing the ramifications of the Fourth Industrial Revolution. The two signed an MOU to cooperate in research in related fields on October 13 after holding a roundtable discussion titled “The Future of Jobs and Inclusive Growth in Korea”. It is the first partnership that the WEF has sealed with an academic institution.The roundtable discussion brought together distinguished guests from politics, non-profit civic organizations, academia, and enterprises including Daejeon Mayor Seon-Taek Kwon, Doosan Group Vice Chairman Lee Hyun-Soon, and Korean Venture Business Association President Ahn Keon-Joon. During the news conference, President Shin said, “This event means a lot because it explores ways in which inclusive growth and job creation can be realized in Korea. To move forward in the new age of the Fourth Industrial Revolution, every country needs to adopt appropriate new policies suitable for their specific market environments. KAIST will contribute to this process for Korea as well as for the global community.” President Shin also said, “Korea has been a fast follower in previous industrial revolutions. Now, we have the momentum to seize the opportunities in the wake of this revolution. KAIST is dedicated to leading Korea into becoming a first mover in the Fourth Industrial Revolution by cooperating with the WEF.” “Two decades later, we will live with considerable number of robots around us. It is possible that our societies in the future will consist of Homo sapiens and Robo sapiens. We need to create new jobs for Homo sapiens to prepare for a society that we will have to coexist with a new industrial tribe. Industries need continuing education to retrain workers for the ever evolving industrial landscape of the future,” President Shin emphasized. Meanwhile, Sonmez pointed out that all stakeholders should participate in understanding the new industrial environment’s ramifications, saying “Societies, governments, public and private sectors, startups, and academia should co-design inclusive models through global efforts. Ethics and influences on the job market should also be taken into consideration.” Sonmez said nine factors such as blockchains, internet of things, artificial intelligence, machine learning, cross-border data blow, drones, 3D printing, autonomous driving, the environment, and precision medicine will take center stage in the Fourth Industrial Revolution, In particular, he said that blockchains, which are a cybersecurity technology for online financial transactions, will bring even bigger changes than the ‘World Wide Web’ has done over the past three decades. “To this end, we will have to work closely with major academic institutes. Through this partnership with KAIST, we will make the fruits of the new industrial environment benefit Koreans and Korean society,” Sonmez added.
2017.10.14
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Postech-KAIST Rivalry Heats Up at the 16th Science War
The 16th Postech-KAIST Science War wrapped up its two-day rivals’ duel at the KAIST campus in Daejeon on September 23. The event was established in 2002 to build a close tie between the two renowned universities for science and technology, and to provide students with an opportunity to demonstrate their talents and abilities. On September 21, a convoy of red Postech buses carrying more than 650 athletes, students, and supporters arrived at the KAIST campus in Daejeon. The two teams competed in eight events including both online and sports event. The night before the actual games started, cheerleading teams from both Postech Cheero and KAIST ELKA kicked off the event. 1st Day (September 22) The hacking tournament marked the beginning of the Science War. The event started at nine in the morning. Both teams had to solve four problems within 12 hours. While the fierce hacking competition was underway, school music bands, including Twenties Dreams, opened up the event with beautiful voices. The soccer game took place in the university stadium. The KAIST soccer team brought the first win to KAIST, and was their second straight victory in soccer. At the outdoor theatre, the evening games, including Artificial Intelligence and E-sports (League of Legend) began. After the E-sports, both KAIST’s and Postech’s music and dance clubs showed amazing performances adding more excitement to the event. Another fun aspect of the event was the ‘evening street food market’. Food trucks and food booths were lined up to satisfy students’ hunger. Talso here were various game booths such as can bowling, balloon darts, and lamp DIY. 2nd Day (September 23) The baseball team marked the second day of the Science War in the Undergraduate Field. The KAIST team won the game by six runs. Science quizzes sealed the Postech-KAIST Science War. Although the KAIST team led at the beginning, the Postech team overtook them by getting bonus point answers correct. This game decided Postech winning this year’s Science War. As a spin-off, a badminton game was held in the Sports Complex and the KAIST team beat the Postech team with ease. Last but not least, a basketball game was held in the Sports Complex. In the last game of the Science War, the KAIST team wiped away the stain of last year’s defeat. At the closing ceremony, famous rappers and school music clubs celebrated the last moments of the Science War. (Jiwon Hwang, Public Relations of the 16th Science War Committee) (The 16th Science War Committee) Cheers to the students committees, participants, and supporters who put every ounce of their effort into successfully running the 16th Postech-KAIST Science War. Day Category Winner Day 1 Hacking Postech Soccer KAIST Artificial Intelligence Postech E-Sports (LoL) Postech Day 2 Baseball KAIST Science Quizzes Postech Badminton (spin-off) KAIST Basketball KAIST (The final tally for KAIST in the Science Wars was eight wins and six losses)
2017.09.27
View 5589
Sangeun Oh Recognized as a 2017 Google Fellow
Sangeun Oh, a Ph.D. candidate in the School of Computing was selected as a Google PhD Fellow in 2017. He is one of 47 awardees of the Google PhD Fellowship in the world. The Google PhD Fellowship awards students showing outstanding performance in the field of computer science and related research. Since being established in 2009, the program has provided various benefits, including scholarships worth $10,000 USD and one-to-one research discussion with mentors from Google. His research work on a mobile system that allows interactions among various kinds of smart devices was recognized in the field of mobile computing. He developed a mobile platform that allows smart devices to share diverse functions, including logins, payments, and sensors. This technology provides numerous user experiences that existing mobile platforms could not offer. Through cross-device functionality sharing, users can utilize multiple smart devices in a more convenient manner. The research was presented at The Annual International Conference on Mobile Systems, Applications, and Services (MobiSys) of the Association for Computing Machinery in July, 2017. Oh said, “I would like to express my gratitude to my advisor, the professors in the School of Computing, and my lab colleagues. I will devote myself to carrying out more research in order to contribute to society.” His advisor, Insik Shin, a professor in the School of Computing said, “Being recognized as a Google PhD Fellow is an honor to both the student as well as KAIST. I strongly anticipate and believe that Oh will make the next step by carrying out good quality research.”
2017.09.27
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