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KAIST to Participate in Summer Davos Forum 2016 in China
A group of KAIST researchers will share their insights on the future and challenges of the current technological innovations impacting all aspects of society, while showcasing their research excellence in artificial intelligence and robotics. Scientific and technological breakthroughs are more important than ever as key agents to drive social, economic, and political changes and advancements in today’s world. The World Economic Forum (WEF), an international organization that provides one of the broadest engagement platforms to address issues of major concern to the global community, will discuss the effects of these breakthroughs at its 10th Annual Meeting of the New Champions, a.k.a., the Summer Davos Forum, in Tianjin, China, June 26-28, 2016. Three professors from the Korea Advanced Institute of Science and Technology (KAIST) will join the Annual Meeting and offer their expertise in the fields of biotechnology, artificial intelligence, and robotics to explore the conference theme, “The Fourth Industrial Revolution and Its Transformational Impact.” The Fourth Industrial Revolution, a term coined by WEF founder, Klaus Schwab, is characterized by a range of new technologies that fuse the physical, digital, and biological worlds, such as the Internet of Things, cloud computing, and automation. Distinguished Professor Sang Yup Lee of the Chemical and Biomolecular Engineering Department will speak at the Experts Reception to be held on June 25, 2016 on the topic of “The Summer Davos Forum and Science and Technology in Asia.” On June 27, 2016, he will participate in two separate discussion sessions. In the first session entitled “What If Drugs Are Printed from the Internet?,” Professor Lee will discuss the impacts of advancements in biotechnology and 3D printing technology on the future of medicine with Nita A. Farahany, a Duke University professor. Clare Matterson, the Director of Strategy at Wellcome Trust in the United Kingdom, will serve as the moderator. The discussants will note recent developments made in the way patients receive their medicine, for example, downloading drugs directly from the internet and the production of yeast strains to make opioids for pain treatment through systems metabolic engineering. They will also suggest how these emerging technologies will transform the landscape of the pharmaceutical industry in the years to come. In the second session, “Lessons for Life,” Professor Lee will talk about how to nurture life-long learning and creativity to support personal and professional growth necessary in an era of the new industrial revolution. During the Annual Meeting, Professors Jong-Hwan Kim of the Electrical Engineering School and David Hyunchul Shim of the Aerospace Department will host, together with researchers from Carnegie Mellon University and AnthroTronix, an engineering research and development company, a technological exhibition on robotics. Professor Kim, the founder of the internally renowned Robot World Cup, will showcase his humanoid soccer-playing micro-robots and display their various cutting-edge technologies such as imaging processing, artificial intelligence, walking, and balancing. Professor Shim will present a human-like robotic piloting system, PIBOT, which autonomously operates a simulated flight program by employing control sticks and guiding an airplane from takeoff to landing. In addition, the two professors will join Professor Lee, who is also a moderator, to host a KAIST-led session on June 26, 2016, entitled “Science in Depth: From Deep Learning to Autonomous Machines.” Professors Kim and Shim will explore new opportunities and challenges in their fields from machine learning to autonomous robotics, including unmanned vehicles and drones. Since 2011, KAIST has participated in the World Economic Forum’s two flagship conferences, the January and June Davos Forums, to introduce outstanding talents, share their latest research achievements, and interact with global leaders. KAIST President Steve Kang said, “It is important for KAIST to be involved in global forums that identify issues critical to humanity and seek answers to solve them, and where our skills and knowledge in science and technology can play a meaningful role. The Annual Meeting in China will become another venue to accomplish this.”
2016.06.27
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Special Lecture by Professor Sung-Hou Kim of UC Berkeley
As part of its special lecture series, the Department of Biological Sciences at KAIST has invited Professor Sung-Hou Kim of the Department of Chemistry at the University of California, Berkeley, to lecture on his research in structural biology. He will speak twice on May 23 and 30, respectively, on the topics “Origin of Universe and Earth—A Narrative” and “Origin of Life and Human Species—A Narrative.” Professor Kim's research addresses the structural basis of molecules to reveal how they communicate with each other to activate or inhibit particular processes in cell growth, cell differentiation, and cancer. Using the single-crystal X-ray diffraction technology, he discovered, for the first time in the world, the three-dimensional (3-D) structure of a transfer RNA (t-RNA) and received much praise for this work from the scientific community. Since then, he has been cited as a candidate for a Nobel Prize in Chemistry for many years. He also examined the 3-D structures of a RAS protein in normal and cancer cells and identified the mutations of the RAS protein as a cause for cancer. His work has assisted in the development of target drugs for cancer treatment. In recent years, he has adopted a computational biology approach to study the structure and function of biological genomics, with which he has tried to predict disease-sensitive genes. Professor Kim graduated from Seoul National University in 1962 and received his Ph.D. degree in chemistry from the University of Pittsburgh in the United States in 1966. He worked at the Massachusetts Institute of Technology (MIT) as a senior research scientist, and has taught at UC Berkeley since 1978.
2016.05.23
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Professor Joonho Choe Appointed as the President of the KSMCB
Professor Joonho Choe of the Biological Sciences Department at KAIST has been elected the 25th president of Korean Society for Molecular and Cellular Biology (KSMCB). His presidency will last one year, beginning on January 1, 2016. Established in 1989, the Society has served as the largest academic gathering in the field of life sciences, holding an international conference every fall. It has more than 12,400 fellows. Professor Choe served as the vice president of KSMC as well as the editor of its journal, Molecules and Cells. He said, “The 2016 International Conference of the KSMCB will take place on October 12-14, 2016 at the COEX Convention and Exhibition Hall in Seoul. This year, we are preparing 20 symposiums and will invite four international renowned keynote speakers in the field including a Nobel Laureate. We hope many people, students and young researchers in particular, from academia and industry will join the conference.” Professor Choe received his doctoral degree from the University of California, Los Angeles (UCLA) after graduating from Seoul National University with his bachelor and master’s degrees.
2016.01.05
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Professor Ki-Jun Jeong Wins the 2015 Dam Yeun Academic Award
The 11th Dam Yeun Academic Award presented by the Korean Society for Biotechnology and Bioengineering (KSBB) to a biologist under 45 years old went to Professor Ki-Jun Jeong of the Chemical and Biomolecular Engineering Department at KAIST. The award ceremony took place on October 13, 2015, at the annual conference of KSBB held at Songdo Convensia in Incheon City. Each year KSBB announces the recipient of the award based on the publications by researchers in the last five years at peer-reviewed international journals or KSBB Journal as well as the record of patent registration and technology transfers. Professor Jeong is recognized for his pioneering research in protein, antibody, cellular engineering, and protein displays and chips.
2015.10.19
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Nature Biotechnology Nominates Sang Yup Lee of KAIST for Top 20 Translational Researchers of 2014
Nature Biotechnology, recognized as the most prestigious journal in the field of biotechnology, has released today its list of the Top 20 Translational Researchers of 2014. Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering at KAIST (Korea Advanced Institute of Science and Technology) ranked seventh in the list. He is the only Asian researcher listed. The journal, in partnership with IP Checkups, a patent analytics firm, presents an annual ranking of researchers based on their paper and patent output. The list includes, among others, each researcher’s most-cited patent in the past five years and their H index, a measurement to evaluate the impact of a researcher’s published work utilizing citation analysis. (More details can be found at http://www.nature.com/bioent/2015/150801/full/bioe.2015.9.html.) American institutions made up the majority of the list, with 18 universities and research institutes, and the remainder was filled by KAIST in Korea and the Commonwealth Scientific and Industrial Research Organization (CSIRO) in Australia. Globally known as a leading researcher in systems metabolic engineering, Professor Lee has published more than 500 journal papers and 580 patents. He has received many awards, including the Citation Classic Award, Elmer Gaden Award, Merck Metabolic Engineering Award, ACS Marvin Johnson Award, SIMB Charles Thom Award, POSCO TJ Park Prize, Amgen Biochemical Engineering Award, and the Ho Am Prize in Engineering.
2015.08.27
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Dr. Hyundoo Hwang Receives a Tenured Position at Monterrey Institute of Technology and Higher Education
Hyundoo Hwang, a former graduate student in the Department of Bio & Brain Engineering at KAIST, has been granted a tenured position at the Monterrey Institute of Technology and Higher Education (ITSEM), Mexico. Dr. Hwang received his bachelor’s, master’s, and doctoral degree at KAIST and started his professorship at Ulsan National Institute of Science & Technology (UNIST) in Korea. He continued his research in the United States as a professor at Georgia Institute of Technology. He has been acknowledged for the development of an advanced nanotechnology for the diagnosis of rare diseases and research in cell signals. He is one of the leading researchers in an international research project in microelectromechanical systems (MEMS) with participation by researchers from over ten countries. He has been active in commercializing biosensor technology in the U.S. and Mexico. Since its establishment in 1943, ITSEM has grown to 33 campuses in 25 cities in Mexico. It is the largest university in Latin America with over 90,000 students (47% of its graduate students has oversea research experience). It recruits over 5,000 international students and professors every year. Dr. Hwang will begin teaching at ITSEM as a professor in the Department of Biomedical Engineering (Ingeniería Biomédica) this fall. He will also conduct research in nano- and micro-technology as a member of Sensors and Devices research group. Professor Gwang Hyun Cho, head of KAIST's Department of Bio and Brain Engineering said that Dr. Hwang’s tenure professorship at ITSEM demonstrated that the academic program at KAIST—from undergraduate to doctoral—was on par with the international standard. He hoped that more talents from the department would seek academic careers in internationally renowned universities around the world.
2015.08.13
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Professor Sang-Yup Lee Receives the Order of Service Merit Red Stripes from the Korean Government
The government of the Republic of Korea named Professor Sang-Yup Lee of the Department of Chemical and Bio-molecular Engineering at KAIST as the fiftieth recipient of the Order of Service Merit Red Stripes on May 19, 2015. This medal is awarded to government employees, officials, and teachers in recognition of their contributions to public services including education. Professor Lee is regarded as a leading scientist in the field of metabolic engineering, genomics, proteomics, metabolomics, and bioinformatics on microorganism producing various primary and secondary metabolites. He contributed significantly to the advancement of bio-based engineering research in Korea. In addition, his research in microorganism metabolic engineering propelled him to the front of his field, making him the world’s founder of systems metabolic engineering, inventing numerous technologies in strain development. Professor Lee has received many patent rights in bioprocess engineering. While at KAIST, he applied for 585 patents and registered 227 patents. In particular, he has applied for 135 patents and registered 99 patents in the past five years, successfully turning research results into commercial applications. Professor Lee said, “I’m glad to contribute to the development of Korean science and technology as a researcher and teacher. I would like to share this honor with my students, master’s and doctoral students in particular, because without their support, it wouldn’t have been possible to pull off the highest level of research results recognized by this medal.”
2015.05.21
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Anti-Cancer Therapy Delivering Drug to an Entire Tumor Developed
KAIST’s Department of Bio and Brain Engineering Professor Ji-Ho Park and his team successfully developed a new highly efficacious anti-cancer nanotechnology by delivering anti-cancer drugs uniformly to an entire tumor. Their research results were published in Nano Letters online on March 31, 2015. To treat inoperable tumors, anti-cancer medicine is commonly used. However, efficient drug delivery to tumor cells is often difficult, treating an entire tumor with drugs even more so. Using the existing drug delivery systems, including nanotechnology, a drug can be delivered only to tumor cells near blood vessels, leaving cells at the heart of a tumor intact. Since most drugs are injected into the bloodstream, tumor recurrence post medication is frequent. Therefore, the team used liposomes that can fuse to the cell membrane and enter the cell. Once inside liposomes the drug can travel into the bloodstream, enter tumor cells near blood vessels, where they are loaded to exosomes, which are naturally occurring nanoparticles in the body. Since exosomes can travel between cells, the drug can be delivered efficiently into inner cells of the tumor. Exosomes, which are secreted by cells that exist in the tumor microenvironment, is known to have an important role in tumor progression and metastasis since they transfer biological materials between cells. The research team started the investigation recognizing the possibility of delivering the anti-cancer drug to the entire tumor using exosomes. The team injected the light-sensitive anti-cancer drug using their new delivery technique into experimental mice. The researchers applied light to the tumor site to activate the anti-cancer treatment and analyzed a tissue sample. They observed the effects of the anti-cancer drug in the entire tumor tissue. The team’s results establish a ground-breaking foothold in drug delivery technology development that can be tailored to specific diseases by understanding its microenvironment. The work paves the way to more effective drug delivery systems for many chronic diseases, including cancer tumors that were difficult to treat due to the inability to penetrate deep into the tissue. The team is currently conducting experiments with other anti-cancer drugs, which are being developed by pharmaceutical companies, using their tumor-penetrating drug delivery nanotechnology, to identify its effects on malignant tumors. Professor Park said, “This research is the first to apply biological nanoparticles, exosomes that are continuously secreted and can transfer materials to neighboring cells, to deliver drugs directly to the heart of tumor.” Picture: Incorporation of hydrophilic and hydrophobic compounds into membrane vesicles by engineering the parental cells via synthetic liposomes.
2015.04.07
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Professor Sangyong Jon Appointed Fellow of AIMBE
Professor Sangyong Jon of the Department of Biological Sciences at KAIST has been appointed a member of the American Institute for Medical and Biological Engineering (AIMBE) fellowship. Established in 1991, AIMBE is a non-profit organization based in Washington, D.C., representing 50,000 individuals and the top 2% of medical and biological engineers. AIMBE provides policy advice and advocacy for medical and biological engineering for the benefit of humanity. It has had about 1,500 fellows over the past 25 years. Among the members, only 110 are non-American nationalities. Following the appointment of Dr. Hae-Bang Lee, the former senior researcher at the Korean Research Institute of Chemical Technology, and Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering at KAIST, Professor Jon is the third Korean to become an AIMBE fellow. He had an induction ceremony for the appointment of his fellowship at the AIMBE’s Annual Event held on March 15-17, 2015 in Washington, D.C. An authority on nanomedicine, Professor Jon has developed many original technologies including multi-functional Theranostics nano particles for the diagnosis and treatment of diseases. He received the Most Cited Paper Award from Theranostics, an academic journal specialized in nanomedicine, last February. Additionally, Professor Jon is a leading researcher in the field of translational medicine, using a multi-disciplinary, highly collaborative, “Bench to Bedside” approach for disease treatment and prevention. He created a biotechnology venture company and transferred research developments to the industry in Korea.
2015.03.12
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The Number of KAIST Doctoral Graduates to Reach Over Ten Thousands
The ten-thousandth doctoral graduate received her degree in the commencement ceremony on February 13, 2015. KAIST has contributed to the development of science, technology, and industry in Korea by fostering talents in advanced science and engineering. Since its establishment forty-four years ago, more than ten-thousand KAIST alumni have received their doctorates. This year’s graduation ceremony took place on February 13, 2015, at the Sports Complex on campus, awarding the ten-thousandth doctoral degree. Dr. Sun-Mi Cho of the Department of Biological Sciences received the ten-thousandth doctoral degree. A graduate of Jeon-Nam Science High School, Dr. Cho also received her Bachelor of Science degree from KAIST. Dr. Cho wrote a dissertation entitled “GABA from reactive astrocytes impairs learning and memory in Alzheimer disease.” Her dissertation adviser was Professor Daesoo Kim of the Department of Biological Sciences. Dr. Cho, who will be a post-doctorate researcher at the Biological Sciences Department, said, “It was my childhood dream to receive a doctorate from KAIST. I cannot believe that I’m the ten-thousandth doctoral graduate, for which I’m very grateful.” She continued, “I hope to become a neuroscientist where I can be of help to the sick.” In 1978, KAIST only had two doctoral graduates, but since 1987 there have been more than one hundred graduates each year, two hundred since 1994, and four hundred since 2000. In 2015, 522 doctoral students graduated. One of the first doctoral graduates, Dong-Yol Yang (class of 1978 in the Mechanical Engineering Department), became a professor at the same department of KAIST. Professor Yang expressed his thoughts on the news, “There was a trend in Korea to go overseas for Ph.D. degrees in the early 1970s, but it changed when KAIST began to select candidates for Master’s degrees in 1973 and Doctoral degrees in 1975. Talented Korean students came to KAIST laboratories, and its graduates were known for their knowledge and skills. Now, we see that the talent is coming from overseas.” At the 2015 Commencement, KAIST conferred 522 Doctoral, 1,241 Master’s, and 915 Bachelor of Science (B.S.) degrees. Since its inception in 1971, KAIST has granted 10,403 doctor's, 26,402 master's, and 51,412 bachelor's degrees. In the picture below, Professor Dong-Yol Yang (left) seats next to Dr. Sun-Mi Cho (right), the recipient of 10,000th doctoral degree.
2015.02.16
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Professor Sang Yup Lee Appointed Founding Board Member of Cell Systems
Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering at KAIST has been appointed a member of the founding editorial board of the newly established journal Cell Systems. Cell Systems will be a sister journal of Cell, one of the three most prestigious scientific journals along with Nature and Science, that publishes a wide range of papers on biological engineering. The first issue of Cell Systems will be published this July. Cell Systems plans to publish innovative discoveries, reviews of various research instruments, and research findings on integrated and quantified systems in the field of biology. Professor Lee is a pioneer in metabolic engineering of microorganism with a focus on biopolymers and metabolites production. He is the editor-in-chief of Biotechnology Journal and serves on the editorial board of numerous international journals. He is also a member of the Global Agenda Council of the World Economic Forum and the Presidential Advisory Committee on Science and Technology in Korea. Professor Lee said, “Cell Systems will present research findings that discuss whole biological systems methodically.” He continued, “I hope many research findings of Korean scholars will be published in Cell Systems, which will become a representative journal of systems biology and systems biological engineering.”
2015.02.13
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Professor Kwang-Hyun Cho Recognzied by "Scientist of the Month" Award
Professor Kwang-Hyun Cho of KAIST’s Department of Bio and Brain Engineering received the “Scientist of the Month” award in February 2015 from the Ministry of Science, ICT, and Future Planning of the Republic of Korea and the National Research Foundation of Korea. The award was in recognition of Professor Cho’s contribution to the advanced technique of controlling the death of cancer cells based on systems biology, a convergence research in information technology (IT) and biotechnology. Professor Cho has published around 140 articles in international journals, including 34 papers in renowned science journals such as Nature, Science, and Cell in the past three years. His work also includes systems biology textbooks and many entries in international academic encyclopaedia. His field, systems biology, is a new biological research paradigm that identifies and controls the fundamental principles of organisms on a systems level. A well-known tumour suppressor protein, p53, is known to suppress abnormal cell growth and promote apoptosis of can cells, and thus was a focus of research by many scientists, but its effect has been insignificant and brought many side effects. This was due to the complex function of p53 that controls various positive and negative feedbacks. Therefore, there was a limit to understanding the protein with the existing biological approach. However, Professor Cho found the kinetic change and function of p53 via a systems biology approach. By applying IT technology to complex biological networks, he also identified the response to stress and the survival and death signal transduction pathways of cardiomyocytes and developed new control methods for cancer cells. Professor Cho said, “This award served as a momentum to turn over a new leaf.” He added, “I hope convergence research such as my field will bring more innovative ideas on the boundaries of academia.”
2015.02.09
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