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Professor Dong Ho Cho Awarded at the Haedong Conference 2017
Professor Dong Ho Cho of the School of Electrical Engineering at KAIST received an award at the 13th Haedong Conference 2017 in Seoul on the first of December.
The Korean Institute of Communications and Information Sciences recognized Professor Cho for his significant contributions in the field of mobile communication networks. He has carried out groundbreaking research on mobile systems, including architecture, protocols, algorithms, optimization, and efficiency analysis.
As a result, he has produced 73 papers in renowned international journals, 138 papers at international conferences, and filed 52 international patents and 121 domestic patents. In addition, he transferred 14 of the patents he filed to Korean and international companies.
2017.12.07 View 5226 -
Expanding Gas Storage Capacity of Nanoporous Materials
A KAIST research team led by Professor Jihan Kim of the Department of Chemical and Biomolecular Engineering has successfully proposed a rational defect engineering methodology that can greatly enhance the gas storage capacity of nanoporous materials. The team conducted a high-throughput computational screening of a large experimental metal-organic framework database to identify 13 candidate materials that could experience significant methane uptake enhancement with only a small proportion of linker vacancy defects.
This research was published online on November 16 in Nature Communications, with M.S. candidate Sanggyu Chong from KAIST as the first author and post-doctorate researcher Günther Thiele from the Department of Chemistry at UC Berkeley as a contributing author.
Metal-organic frameworks, hereinafter MOF, are crystalline nanoporous materials that are comprised of metal clusters and organic linkers continuously bound together by coordination bonds. Due to their ultrahigh surface areas and pore volumes, they have been widely studied for various energy and environment applications.
Similar to other crystalline materials, MOFs are never perfectly crystalline and are likely to contain several different types of defects within their crystalline structures. Among these defects, linker vacancy defects, or the random absence of linker vacancies in their designated bonding positions, are known to be controllable by practicing careful control over the synthesis conditions.
The research team combined the concepts of rational defect engineering over the linker vacancy defects and the potential presence of inaccessible pores within MOFs to propose a methodology where controlled the introduction of linker vacancy defects could lead to a dramatic enhancement in gas adsorption and storage capacities.
The study utilized a Graphic Processing Unit (GPU) code developed by Professor Kim in a high-throughput computational screening of 12,000 experimentally synthesized MOFs to identify the structures with significant amounts of pores that were inaccessible for methane. In determining the presence of inaccessible pores, a flood-fill algorithm was performed over the energy-low regions of the structure, which is the same algorithm used for filling an area with color in Microsoft Paint.
For the MOFs with significant amounts of inaccessible pores, as determined from the screening, the research team emulated linker vacancy defects in their crystalline structures so that the previously inaccessible pores would be newly merged into the main adsorption channel with the introduction of defects for additional surface area and pore volume available for adsorption. The research team successfully identified 13 structures that would experience up to a 55.56% increase in their methane uptake with less than 8.33% of the linker vacancy defects.
The research team believes that this rational defect engineering scheme can be further utilized for many other applications in areas such as selective adsorption of an adsorbate from a gas mixture and the semi-permanent capture of gas molecules.
This research was conducted with the support of the Mid-career Research Program of the National Research Foundation of Korea.
Figure1. A diagram for flood fill algorithm and example of identification of inaccessible regions within the MOFs, using the flood fill algorithm
Figure2. Methane energy contours before and after detect introduction
2017.12.04 View 7173 -
CBNU Wins the First AI World Cup 2017
KAIST hosted the first AI World Cup 2017. A total of 26 teams, comprised of Korean undergraduates or graduates, participated in AI Soccer, AI Commentator, and AI Reporter competitions.
On the first of December, the final tournament for AI Soccer was held in the KI Building. More than 200 people came to watch the first AI soccer match based on the Deep-Q Network Learning. The games were commentated by two KAIST students who humorously interpreted the games, catching people’s attention.
In AI Soccer, 18 teams participated, and KAIST BML (KAIST), AIM (KAIST), WISRL (KAIST), and AR Lab (Chonbuk National University) made it to the final four. Each team had its own unique style and strategy.
After some fierce contests, the win went to AR Lab, which showed fearless attacks throughout the game. Having no goalkeeper, AR Lab focused on attacking. According to the team, instead of training individual players, they concentrated on training a manager that directed the players, giving them a choice when to attack and defend.
(AR Lab from Chonbuk National University, the winning team of AI Soccer tournament)
Different from humans playing soccer, it was interesting to see how AI robots self-improved their movements while playing the games.
For AI Commentators, judges looked for a team with the most accuracy, forecasting ability, and fluency. Four teams competed, and the Yally team won the title.
For AI Reporters, which required informativeness and reliability, four teams participated, and the prize went to a team, named Deep CMT (KAIST).
Although this year’s games only included domestic universities, KAIST plans to extend participation to university students from around the world in the future, and hopes that the AI World Cup 2017 will become the foundation for launching the next games on an international level.
2017.12.04 View 4659 -
Seoul Climate-Energy Conference Seeks Global Sustainability
(President Shin and Former UN Secretary General at the Seoul Climate Change-Energy Conference)
Global leaders from both the private and public sectors discussed creative ways to seek inclusive green growth and sustainable development at the Seoul Climate-Energy Conference on November 24 in Seoul. The annual conference was co-hosted by KAIST and the Coalition for Our Common Future under the theme “Creating New Momentum for the Paris Agreement and a Sustainable Future.”
More than 100 global leaders participated in the forum including the Director General Frank Rijsbermanof the Global Green Growth Institute and Executive Director Howard Bamsey of the Green Climate Fund. Former UN Secretary-General Ban Ki-Moon, who played a significant role in the signing of the Paris Agreement, was the keynote speaker.
This year’s conference focused on Korea’s low carbon-energy transition and the Fourth Industrial Revolution to be aligned with green growth. At the conference, speakers and participants reviewed the progress of the decisions made by the UN Framework Convention on Climate Change (UNFCCC) COP23 in Bonn, Germany. The conference discussed topics of global collaboration for new climate regimes, green energy infrastructure, the Asia super grid, financing green energy, smart green cities, and new mobility.
President Sung-Chul Shin emphasized global action and greater resilience toward climate change in his opening remarks. He said, “Today’s climate change can be attributed directly to the past three industrial revolutions. As industrialization continues, we must not make future generations pay the cost of this Fourth Industrial Revolution.” He explained that it is increasingly complicated to address climate change and energy issues because even though the use of energy consumption will continue to increase, energy policies are interwoven with global politics.
He stressed three keywords to better address this global problem: innovation, collaboration, and speed. First he emphasized innovation as a priority for future success as it is hard to retain confidence without innovation.
He noted KAIST has made sustainability initiatives in the fields of EEWS (energy, environment, water, sustainability) and green mobility. He also noted the importance of collaboration as industries are moving beyond a single discipline. KAIST is making collaborations in R&D and sustainability sectors, such as Saudi Aramco’s CO2 management center in KAIST. Finally, he explained that the speed of new transformation will be beyond our imagination, and governments should work efficiently to address issues in a fast manner.
Meanwhile, Secretary-General Ban called for global unity in addressing climate change. He strongly emphasized that countries should make agreements not of willingness but of action, and that politicians should realize that this global agenda should be given top priority above domestic politics. He addressed how the world is experiencing the most powerful and destructive effects of climate change which makes active participation in the Paris Agreement increasingly important.
He expressed his concern that the richest and most powerful countries are backing off, emphasizing the role of these countries as both global leaders and top producers of CO2. He also shared his hopes that the OECD will continue to work to fill the absence of the United States, and stressed the importance of acquiring 10 billion USD by 2020 to fund mitigation and adaptation technologies for developing countries’ CO2 emissions.
Click for President Shin's opening remarks
2017.11.29 View 7397 -
Technology Detecting RNase Activity
(Ph.D. candidate Chang Yeol Lee)
A KAIST research team of Professor Hyun Gyu Park at Department of Chemical and Biomolecular Engineering developed a new technology to detect the activity of RNase H, a RNA degrading enzyme. The team used highly efficient signal amplification reaction termed catalytic hairpin assembly (CHA) to effectively analyze the RNase H activity. Considering that RNase H is required in the proliferation of retroviruses such as HIV, this research finding could contribute to AIDS treatments in the future, researchers say.
This study led by Ph.D. candidates Chang Yeol Lee and Hyowon Jang was chosen as the cover for Nanoscale (Issue 42, 2017) published in 14 November.
The existing techniques to detect RNase H require expensive fluorophore and quencher, and involve complex implementation. Further, there is no way to amplify the signal, leading to low detection efficiency overall. The team utilized CHA technology to overcome these limitations. CHA amplifies detection signal to allow more sensitive RNase H activity assay.
The team designed the reaction system so that the product of CHA reaction has G-quadruplex structures, which is suitable to generate fluorescence. By using fluorescent molecules that bind to G-quadruplexes to generate strong fluorescence, the team could develop high performance RNase H detection method that overcomes the limitations of existing techniques. Further, this technology could screen inhibitors of RNase H activity.
The team expects that the research finding could contribute to AIDS treatment. AIDS is disease caused by HIV, a retrovirus that utilizes reverse transcription, during which RNA is converted to DNA. RNase H is essential for reverse transcription in HIV, and thus inhibition of RNase H could in turn inhibit transcription of HIV DNA.
Professor Park said, “This technology is applicable to detect various enzyme activities, as well as RNase H activity.” He continued, “I hope this technology could be widely used in research on enzyme related diseases.”
This study was funded by Global Frontier project and Mid-career Researcher Support project of the Ministry of Science and ICT.
2017.11.28 View 6215 -
Dr. Steven Chu Talks on Sustainable Energy Policy at KAIST
Nobel Laureate in physics and former US Energy Secretary Steven Chu called for concerted efforts to develop a more sustainable energy policy and portfolio at a lecture held at KAIST and a forum in Seoul on November 23.
A policy with an energy mix including nuclear power and renewable energy could be ideal for retaining a stable energy supply given Korea’s very limited geographical conditions, Chu said during the Future Energy Forum in Seoul. He also held a lecture at KAIST’s Daejeon campus on “Climate Change, the Importance of Science and Policy in Achieving a Sustainable Future.”
He said that unlike the United States, Korea and Japan have geographical limitations for generating enough renewable energy. "Wind speeds of more than 10 meters per second would allow wind power generation, but, South Korea's southernmost wind speed in Jeju is less than 8 meters per second, and the amount of sunshine is lower than in the Middle East. It is ideal to combine renewable energy with nuclear power plants," he said.
Chu also stressed the role of science in achieving a sustainable future, citing many cases in foreign countries. For instance, Germany once decided to do away with nuclear power. However, their initial plan does not directly raise energy efficiency and the proportion of fossil fuels has led to an increase in the environmental issue of fine particular matter as well as carbon dioxide emission increases.
He said that in the long term, renewable energy will emerge as major alternative resources, stressing the role of science in achieving a sustainable future. Without this alternative, we will eventually burn more fossil fuels and pollute the air.
Chu also said that nuclear waste and safe plant operation will be a big concern, but it is technologically viable since Korea has already proven its prowess in nuclear power plant building and safety technology.
Chu added, "Research in chemical energy storage through novel electrochemistry may lead to solutions, but for the next half century we will need additional energy-on-demand and carbon-free sources of energy from proven technologies."
"While science, innovation and technology will no doubt lead to better solutions, sound government policies are needed to advance the transition to carbon-free energy needed to achieve a more sustainable world," he said.
After serving as the US Secretary of Energy for four years from 2009 to 2013, Professor Chu returned to Stanford University, and currently holds a position of the William R. Kenan, Jr. Professor of Physics as well as Professor in the Department of Molecular and Cellular Physiology.
Professor Chu is known for his research at Bell Labs and Stanford University regarding the cooling and trapping of atoms with laser light, for which he won the Nobel Prize in Physics in 1997.
2017.11.24 View 4270 -
Strengthening Industry-Academia Cooperation with LG CNS
On November 20, KAIST signed an MoU with LG CNS for industry-academia partnership in education, research, and business in the fields of AI and Big Data. Rather than simply developing education programs or supporting industry-academia scholarships, both organizations agreed to carry out a joint research project on AI and Big Data that can be applied to practical business.
KAIST will collaborate with LG CNS in the fields of smart factories, customer analysis, and supply chain management analysis.
Not only will LG CNS offer internships to KAIST students, but it also will support professors and students who propose innovative startup ideas for AI and Big Data. Offering an industry-academia scholarship for graduate students is also being discussed. Together with LG CNS, KAIST will put its efforts into propose projects regarding AI and Big Data in the public sector.
Furthermore, KAIST and LG CNS will jointly explore and carry out industry-academia projects that could be practically used in business. Both will carry out the project vigorously through strong cooperation; for instance, LG CNS employees can be assigned to KAIST, if necessary. Also, LG CNS’s AI and Big Data platform, called DAP (Data Analytics & AI Platform) will be used as a data analysis tool during the project and the joint outcomes will be installed in DAP.
KAIST professors with expertise in AI deep learning have trained LG CNS employees since the Department of Industrial & Systems Engineering established ‘KAIST AI Academy’ in LG CNS last August.
“With KAIST, the best research-centered university in Korea, we will continue to lead in developing the field of AI and Big Data and provide innovative services that create value by connecting them to customer business,” Yong Shub Kim, the CEO of LG CNS, highlighted.
2017.11.22 View 9617 -
Professor Je-Kyun Park, Awarded by The Korean BioChip Society
On November 9, Je-Kyun Park from the Department of Bio and Brain Engineering at KAIST received an award from the 2017 Fall Meeting of The Korean BioChip Society held in Paradise Hotel Busan, Korea. This year’s meeting recognized Professor Park for developing lab-on-a-chip and microfluidic analytical technologies.
The Korean BioChip Society is a corporation of biochip professional established in 2006 for the development of biochip technology. Every year, the Society selects a recipient based on the nominees’ academic achievements and contributions to bio-fusion industry.
Professor Park served on the international editorial boards of renowned international journals in related fields, including Biosensors and Bioelectronics and Lab on a Chip. He was also the Committee Chairman of MicroTas in 2015.
2017.11.22 View 6828 -
New Photocatalyst Converts Carbon Dioxide to 99% Pure Fuel
(Professor Song, Ph.D. candidates Kim, and Lim (from left))
A KAIST research team led by Professor Hyunjoon Song of the Department of Chemistry developed a metal oxide nanocatalyst that converts carbon dioxide to 99% pure methane. This technology directly uses sunlight to convert carbon dioxide into methane, which is more efficient in terms of energy storage capacity, compared to the conventional way of storing the electricity produced by solar cells in batteries. The research team used cheap catalytic materials to significantly enhance the reaction efficiency and selectivity of the chemical energy storage method.
This research was conducted as a joint research project with Professor Ki Min Nam at Mokpo National University with co-first authors Dr. Kyung-Lyul Bae and Ph.D. candidates Jinmo Kim and Chan Kyu Lim. The study was published in Nature Communications on November 7.
Although there is growing interest in sunlight as an energy resource, its usage has been limited to daytime and the power output varies with the weather. If sunlight could be directly converted to chemical energy, such as fuel, the limitations of energy storage and its usage could be overcome. In particular, the usage of sunlight to convert carbon dioxide, a main cause of the greenhouse effect in our atmosphere, is of great interest since both energy and environmental issues can be addressed. However, the stability of carbon dioxide made it difficult to convert it to other molecules. Thus, there was a need for a catalyst with enhanced efficiency and selectivity.
Professor Song’s team synthesized zinc oxide nanoparticles, often used in sun cream. The nanoparticles were then bound to copper oxide as single particles, forming a colloidal form of zinc oxide-copper oxide nanoparticles. Zinc oxides produce high energy electrons using light, and this energy is used to convert carbon dioxide into methane. Further, zinc oxide can also produce electrons with light and transfer the electrons to copper oxide. Similar to the principles of photosynthesis in leaves, the electron transfer reaction could be maintained for a long time. As a consequence, although the reaction was conducted in aqueous solution, methane of 99% purity could be obtained from carbon dioxide.
Conventional heterogeneous photocatalysts were in solid powder form with irregular structures and were not dispersed in water. Professor Song’s team used a nanochemical synthesis method to control the structure of the catalyst particles to be regular and maintained over a large surface area. This led to increasing carbon dioxide conversion activity by hundreds of fold in solution compared to existing catalysts.
Professor Song said, “A long time will be needed for the commercialization of the direct conversion reaction of carbon dioxide using sunlight. However, the precise control of catalyst structures at nanoscale would enhance the efficiency of photocatalyst reactions.” He continued, “Applying this method to various phtocatalysts will maximize the catalysts performance.”
(Figure 1. Scheme for carbon dioxide conversion reaction using nano photocatalyst in aqueous solution)
(Figure 2. Structure, photocatalytic CO2 conversion, and stability of ZnO-Cu2O nanocatalyst )
2017.11.13 View 7885 -
IDKAIST Graduation Show, Interative and Innovative Works
Undergraduate students from the Department of Industrial Design at KAIST opened up their graduation show in the Industrial Design Building for eight days in KAIST from November 10 and another four days in Coex, Seoul from December 7.
The students showcased their creative and novel works in the exhibition. Some designs successfully showed change concepts such as for mixing straws. There were also several projects designed to meet individual demand, such as a customized shoe-making application and personal makeup colorings.
Since the establishment of its undergraduate program in 1983, the department has held a graduation show to demonstrate four years of the students’ academic work and research performance to KAIST members, externals specialists, and the public.
Professor Daniel Saakes, who is in charge of the show, said, “Please come by the show and support the 28 students for their hard work. This year, students’ projects are more socially-oriented through applications and social media, making them easily approachable for consumers.”
2017.11.13 View 5886 -
WEF-KAIST to Host a Forum Next April in Korea
(President Shin poses with Chairman Schwab at the meeting in Dubai)
President Sung-Chul Shin and Executive Chairman Klaus Schwab of the World Economic Forum agreed to co-host the Fourth Industrial Revolution Forum next April in Seoul during a meeting at the WEF Global Future Councils 2017 held in Dubai November 11-12.
Next April’s forum will be a follow-up event of the roundtable discussion KAIST and the WEF Center for the Fourth Industrial Revolution co-hosted in October in Seoul. The two hosted the roundtable discussion titled “Mastering the Fourth Industrial Revolution: The Future of Jobs and Inclusive Growth in Korea.”
During the annual meeting in Dubai, Chairman Schwab expressed his deep appreciation to President Shin for hosting the roundtable discussion and proposed a full-fledged forum in partnership with KAIST once again, which Chairman Schwab will be scheduled to attend.
Chairman Schwab emphasized once again that Korea, who has the world’s top high-end technologies such as 5G telecommunications and semiconductor memory, will be the best fit to realize the Fourth Industrial Revolution most rapidly. He also expressed his great interest in the city of Daejeon in which is being considered to become the Special City for the Fourth Industrial Revolution.
The Global Future Council of the WEF is the interdisciplinary knowledge network dedicated to promoting innovative thinking on the future. The annual council convenes in Dubai the most relevant and knowledgeable thought leaders from academia, government, business, and civil society to challenge conventional thinking and develop new insights and perspectives on key global systems, as well as the impact and governance of key emerging technologies. This year, more than 850 world-leading experts from 74 countries participated.
Under the theme of ‘Vision 2030,’ participants explored systematic changes in key areas such as energy, mobility, and infrastructure while reflecting on the impact of technological breakthroughs in artificial intelligence, biotechnology, and other areas related to the Fourth Industrial Revolution.
2017.11.13 View 7819 -
Mutant Gene Network in Colon Cancer Identified
The principles of the gene network for colon tumorigenesis have been identified by a KAIST research team. The principles will be used to find the molecular target for effective anti-cancer drugs in the future. Further, this research gained attention for using a systems biology approach, which is an integrated research area of IT and BT.
The KAIST research team led by Professor Kwang-Hyun Cho for the Department of Bio and Brain Engineering succeeded in the identification. Conducted by Dr. Dongkwan Shin and student researchers Jonghoon Lee and Jeong-Ryeol Gong, the research was published in Nature Communications online on November 2.
Human cancer is caused by genetic mutations. The frequency of the mutations differs by the type of cancer; for example, only around 10 mutations are found in leukemia and childhood cancer, but an average of 50 mutations are found in adult solid cancers and even hundreds of mutations are found in cancers due to external factors, such as with lung cancer.
Cancer researchers around the world are working to identify frequently found genetic mutations in patients, and in turn identify important cancer-inducing genes (called ‘driver genes’) to develop targets for anti-cancer drugs. However, gene mutations not only affect their own functions but also affect other genes through interactions. Therefore, there are limitations in current treatments targeting a few cancer-inducing genes without further knowledge on gene networks, hence current drugs are only effective in a few patients and often induce drug resistance.
Professor Cho’s team used large-scale genomic data from cancer patients to construct a mathematical model on the cooperative effects of multiple genetic mutations found in gene interaction networks. The basis of the model construction was The Cancer Genome Atlas (TCGA) presented at the International Cancer Genome Consortium. The team successfully quantified the effects of mutations in gene networks to group colon cancer patients by clinical characteristics.
Further, the critical transition phenomenon that occurs in tumorigenesis was identified using large-scale computer simulation analysis, which was the first hidden gene network principle to be identified. Critical transition is the phenomenon in which the state of matter is suddenly changed through phase transition. It was not possible to identify the presence of transition phenomenon in the past, as it was difficult to track the sequence of gene mutations during tumorigenesis.
The research team used a systems biology-based research method to find that colon cancer tumorigenesis shows a critical transition phenomenon if the known driver gene mutations follow sequentially. Using the developed mathematical model, it can be possible to develop a new anti-cancer targeting drug that most effectively inhibits the effects of many gene mutations found in cancer patients. In particular, not only driver genes, but also other passenger genes affected by the gene mutations, could be evaluated to find the most effective drug targets.
Professor Cho said, “Little was known about the contribution of many gene mutations during tumorigenesis.” He continued, “In this research, a systems biology approach identified the principle of gene networks for the first time to suggest the possibility of anti-cancer drug target identification from a new perspective.”
This research was funded by the Ministry of Science and ICT and the National Research Foundation of Korea.
Figure1. Formation of giant clusters via mutation propagation
Figure2. Critical transition phenomenon by cooperative effect of mutations in tumorigenesis
2017.11.10 View 7364