TE
-
KAIST Conducts Safety Awareness Campaign for Research and Experiment
KAIST had an opening ceremony to hold its first “Safety Awareness Campaign for Research and Experiment” on 13th May. Over 100 people attended the ceremony, including President Steve Kang, Provost Gyu-Ho Park, and the Dean of the Administration Office Jae-Nam Lee, as well as the Chief of the Department of Research Environment Safety from the Ministry of Science, ICT and Future Planning, Republic of Korea.
On the day of the event, Year 2014 was proclaimed as the first year of accident-free KAIST research and laboratory facilities.
A certificate of merit was awarded to promote safe and comfortable research environments. The Department of Civil and Environmental Engineering, KAIST, was selected as the department with the best lab safety management and the Department of Mechanical Engineering as the second.
Along with the merit award ceremony, the results of the “7th Research and Laboratory Safety Campaign Contest” were announced: “Lady First When Dating, Safety First When Experimenting!” written by Jong-Su Bae from the Department of Mechanical Engineering was selected as the best slogan, and Hyeon-Chae Noh from the Department of Civil and Environmental Engineering received the award for best poster.
President Steve Kang said, “KAIST is constantly striving to establish a comprehensive safety management system and to promote a safe research and laboratory environment,” and “To ensure the safety of KAIST and its members, we will be as supportive as possible.”
Below is the winner of the poster from the 7th Research and Laboratory Safety Campaign Contest.
What Would You Rather Wear? Gloves or Bandages?
Gloves worn in laboratories are protection from hazardous materials that students and researchers may come in contact with. The poster emphasizes the importance of wearing protective gloves when conducting research or experiment.
2014.05.19 View 7583 -
Opening of International Kitchen at KAIST
KAIST has renovated its International Kitchen on campus which will serve 850 international faculty members and students for their cooking, meal service, and networking. The kitchen, composed of a kitchen and cafeteria, is equipped to prepare a wide variety of food, with a large kitchen countertop, cabinets, and a refrigerator to accommodate everything necessary to cook and prepare meals for large groups.
An opening ceremony to celebrate the brand new International Kitchen was held on May 15, 2014, with the participation of President Steve Kang and international members.
President Kang said, “KAIST has been working quite hard to provide its international faculty and students with the best possible environment for their education and research. We offer a full coverage of healthcare and free dormitories to our international students, as well as newly built apartments to our international faculty members. The International Kitchen is an extension of such efforts.”
The international students or faculty who wish to use the International Kitchen need to register for the membership. The kitchen will be voluntarily operated and managed by the registered members.
2014.05.19 View 6158 -
Immune Evasion Mechanism of Hepatitis C Virus Revealed
Professor Ui-Cheol Shin
Inhibiting major histocompatibility complex [MHC] class I protein expression, T cell immune response is evaded.
The research will be a great help to the development of C hepatitis vaccine.
Roughly 1-2% of the population in Korea is known to be infected with Hepatitis C. Most Hepatitis C Virus (HCV) infections progress to a chronic disease and can cause liver cirrhosis or liver cancer, which may lead to death.
Unlike Hepatitis type A or B, there is no vaccine for Hepatitis C Virus and therefore avoiding exposure to the virus is the best known method of prevention. However, a team of researchers at KAIST has produced research results, which may contribute significantly to the vaccine development.
KAIST Graduate School of Medical Sciences & Engineering’ Professor Ui-Cheol Shin and his team have successfully identified why Hepatitis C Virus does not cause an immune response within the human body. The research results were published in the May edition of The Journal of Gastroenterology, a world-renowned journal in the field of gastroenterology.
The immune response occurs to eliminate the virus that has invaded our body. During this process, a major histocompatibility complex [MHC] class I plays a key role in inducing T cell response, which is needed for the elimination of virus-infected cells.
When a cell is infected by a virus, a substance called interferon causes the increased expression of major histocompatibility complex class I. T cell recognizes the increased MHC class I and therefore finds the virus-infected cells.
However, the effect that Hepatitis C Virus has on major histocompatibility complex class I has not been clearly identified until now.
The research team has revealed, using a cell culture for infection systems, that the Hepatitis C Virus suppresses the expression of major histocompatibility complex class I. Also, the mechanism to prove that HCV activates a protein called PKR within the cell to inhibit MHC class I protein expression was identified at a molecular level.
In this study, researchers established the hypothesis that regulating PKR protein in the cell can enhance the T cell immune response, which was then proved through experiments.
Professor Ui-Cheol Shin said, “There are a lot of new drugs to treat Hepatitis C Virus, while its vaccine has not been developed yet. Revealing the HCV immune evasion mechanism will help stimulate momentum for the HCV vaccine development.”
The first author of the journal, Dr. Won-Seok Kang is a graduate from Yonsei College of Medicine. After earning his medical degree, he has continued his training as a ‘doctor-scientist’ at KAIST Graduate School of Medical Sciences & Engineering to study Hepatitis C Virus immune evasion mechanism in this research.
Hepatitis C Virus activates PKR-eIF2a pathway, which inhibits the major histocompatibility complex class I, and therefore weakens the T cell activation to the viral activity.
2014.05.19 View 10455 -
KAIST Made Great Improvements of Nanogenerator Power Efficiency
The energy efficiency of a piezoelectric nanogenerator developed by KAIST has increased by almost 40 times, one step closer toward the commercialization of flexible energy harvesters that can supply power infinitely to wearable, implantable electronic devices.
NANOGENERATORS are innovative self-powered energy harvesters that convert kinetic energy created from vibrational and mechanical sources into electrical power, removing the need of external circuits or batteries for electronic devices. This innovation is vital in realizing sustainable energy generation in isolated, inaccessible, or indoor environments and even in the human body.
Nanogenerators, a flexible and lightweight energy harvester on a plastic substrate, can scavenge energy from the extremely tiny movements of natural resources and human body such as wind, water flow, heartbeats, and diaphragm and respiration activities to generate electrical signals. The generators are not only self-powered, flexible devices but also can provide permanent power sources to implantable biomedical devices, including cardiac pacemakers and deep brain stimulators.
However, poor energy efficiency and a complex fabrication process have posed challenges to the commercialization of nanogenerators. Keon Jae Lee, Associate Professor of Materials Science and Engineering at KAIST, and his colleagues have recently proposed a solution by developing a robust technique to transfer a high-quality piezoelectric thin film from bulk sapphire substrates to plastic substrates using laser lift-off (LLO).
Applying the inorganic-based laser lift-off (LLO) process, the research team produced a large-area PZT thin film nanogenerators on flexible substrates (2cm x 2cm).
“We were able to convert a high-output performance of ~250 V from the slight mechanical deformation of a single thin plastic substrate. Such output power is just enough to turn on 100 LED lights,” Keon Jae Lee explained.
The self-powered nanogenerators can also work with finger and foot motions. For example, under the irregular and slight bending motions of a human finger, the measured current signals had a high electric power of ~8.7 μA. In addition, the piezoelectric nanogenerator has world-record power conversion efficiency, almost 40 times higher than previously reported similar research results, solving the drawbacks related to the fabrication complexity and low energy efficiency.
Lee further commented,
“Building on this concept, it is highly expected that tiny mechanical motions, including human body movements of muscle contraction and relaxation, can be readily converted into electrical energy and, furthermore, acted as eternal power sources.”
The research team is currently studying a method to build three-dimensional stacking of flexible piezoelectric thin films to enhance output power, as well as conducting a clinical experiment with a flexible nanogenerator.
This research result, entitled “Highly-efficient, Flexible Piezoelectric PZT Thin Film Nanogenerator on Plastic Substrates,” was published as the cover article of the April issue of Advanced Materials. (http://onlinelibrary.wiley.com/doi/10.1002/adma.201305659/abstract)
YouTube Link: http://www.youtube.com/watch?v=G_Fny7Xb9ig
Over 100 LEDs operated by self-powered flexible piezoelectric thin film nanogenerator
Flexible PZT thin film nanogenerator using inorganic-based laser lift-off process
Photograph of large-area PZT thin film nanogenerator (3.5cm × 3.5cm) on a curved glass tube and 105 commercial LEDs operated by self-powered flexible piezoelectric energy harvester
2014.05.19 View 13599 -
Professor Jae-Kyu Lee Elected to Head the Association for Information Systems
Jae Kyu Lee, HHI (Hyundai Heavy Industries, Co., Ltd.) Chair Professor, College of Business at KAIST, was elected to lead the world major academic society, Association for Information Systems (AIS), from July 2015 to June 2016. Professor Lee will be the first Korean to serve the organization as president. From July 2014 to June 2015, he will serve as president-elect.
Currently, Professor Lee is the Director of EEWS (Energy, Environment, Water, and Sustainability) Research Center at KAIST, focusing on research and development in finding solutions to critical issues facing humanity. He also played a pivotal role in the conclusion of a memorandum of understanding between HHI and KAIST in June 2013 to establish HHI-KAIST EEWS Research Center within the KAIST campus.
The AIS is the premier professional association for individuals and organizations who lead the research, teaching, practice, and study of information systems worldwide.
A news article on his appointment:
Asian Scientist, May 16, 2014
Korean Engineer To Lead The Association For Information Systems
http://www.asianscientist.com/academia/korean-engineer-lead-association-information-systems-2014/
2014.05.19 View 10034 -
Dr. Sung-Gu Kim of KARI receives the 10th KAIST Jung-Hun Cho Academic Award
KAIST President Steve Kang awarded the 10th "KAIST Jung-Hun Cho Academic Award" to Dr. Sung-Gu Kim of Korea Aerospace Research Institute (KARI) along with Byeong-Sup Park, a graduate student of KAIST Aerospace Engineering, Hee-Won Chae of Korea University, and Jin-Hyung Noh of Kongju National University High School on May 13, 2014.
Dr. Sung-Gu Kim was recognized for his development of a 30-ton class reproduction cooling burner and the securing of essential factor technology for liquid-fuel rocket engines on the Naro project.
The KAIST Jung-Hun Cho Academic Award was established to commemorate Jung-Hun Cho who was killed while researching in the rocket laboratory on May 13, 2003. From 2005, young scientists from the Aerospace Engineering field have been recognized every year. One student each from KAIST, Korea University, and Kongju National University High School, where the honorary doctorate Dr. Cho attended, has been chosen as a scholarship recipient.
The KAIST Jung-Hun Cho Academic Award was established with USD 460,000 in funds donated from Cho's family.
2014.05.17 View 8800 -
KAIST leaps to 2nd place in 2014 QS Asian University Rankings
The highest record ever made by a Korean university since the rankings were published in 2009
KAIST jumped four places to rank #2 from #6 last year, following the National University of Singapore
In the "2014 Quacquarelli Symonds (QS) University Rankings: Asia," KAIST advanced four places compared to 2013 and was ranked 2nd best university in Asia.
QS, an English institution for global university evaluation, and Chosun Newspaper, a leading daily newspaper in Korea, announced the results of the QS Asia University Rankings on April 12th. The result was a record high for a Korean University since the start of annual rankings in 2009.
KAIST has consistently ranked within the top ten, ranking 7th in 2009 and 2012, and 6th in 2013. The sudden jump from the 6th to the 2nd place was attributed to the increase in the number of published papers per professor and the number of citations per paper. In particular, KAIST received high marks for research contributions, which shows that the young faculty members hired since 2006 is now becoming very productive.
For details regarding the 2014 QS University Rankings: Asia, please visit
http://www.topuniversities.com/university-rankings-articles/asian-university-rankings/top-10-universities-asia-2014.
President Steve Kang of KAIST commented, “We are reaping the rewards of recruiting some of the most promising young professors. KAIST will continue its development towards becoming one of the top ten universities in the world.”
The QS Asia University Rankings have evaluated higher education institutions of Asia for the past six years. It evaluates 491 universities across 17 nations. Criterion for evaluation includes academic evaluation (30%), number of published papers per staff (15%), citation frequency (15%), number of students per staff (20%), alumni reputation, and internationalization (10%).
Please also refer to the Korean-American Science and Technology News (KASTN), dated June 4, 2014, for further information on the rankings.
Another Rankings, Pages 4-5
Chosun Ilbo, May 12, 2014
“Chosun-QS Rankings”
KAIST Soars to 2nd Place in Asian Rakings
http://www.phy.duke.edu/~myhan/b_14-12.pdf
2014.05.14 View 12904 -
Clear Display Technology Under Sunlight Developed
The late Professor Seung-Man Yang
The last paper of the late Professor Seung-Man Yang, who was a past master of colloids and fluid mechanics
Practical patterning technology of the next generation optical materials, photonic crystals
The mineral opal does not possess any pigments, but it appears colorful to our eyes. This is because only a particular wavelength is reflected due to the regular nano-structure of its surface. The material that causes selective reflection of the light is called photonic crystals.
The deceased Professor Seung-Man Yang and his research team from KAIST’s Chemical and Biomolecular Engineering Department ha ve developed micro-pattern technology using photolithographic process. This can accelerate the commercialization of photonic crystals, which is hailed as the next generation optics material.
The research results were published in the April 16th edition of Advanced Materials, known as the most prestigious world-renowned journal in the field of materials science.
The newly developed photonic crystal micro-pattern could be used as a core material for the next generation reflective display that is clearly visible even under sunlight. Since it does not require a separate light source, a single charge is enough to last for several days.
Until now, many scientists have endeavored to make photonic crystals artificially, however, most were produced in a lump and therefore lacked efficiency. Also, the low mechanical stability of the formed structure prevented from commercialization.
In order to solve these problems, the research team has copied the nano-structure of opals.
Glass beads were arranged in the same nano-structure as the opal on top of the photoresist material undergoing photocuring by ultraviolet light. The glass beads were installed in the photoresist materials, and UV light was selectively exposed on micro regions. The remaining region was developed by photolithographic process to successfully produce photonic crystals in micro-patterns.
The co-author of the research, KAIST Chemical and Biomolecular Engineering Department’s Professor Sin-Hyeon Kim, said, “Combining the semiconductor process technology with photonic crystal pattern technology can secure the practical applications for photonic crystals.”He also predicted “This technology can be used as the key optical material that configures the next generation reflective color display device with very low power consumption.”
The late Professor Seung-Man Yang was a world-renowned expert in the field of colloids and fluid mechanics. Professor Yang published over 193 papers in international journals and continued his research until his passing in last September.
He received Du Pont Science and Technology Award in 2007, KAIST Person of the Year 2008, Gyeong-Am Academy Award in 2009, as well as the President’s Award of the Republic of Korea in March 2014. The researchers devoted the achievement of this year’s research to Professor Yang in his honor.
Research was conducted by KAIST Photonic-fluidic Integrated Devices Research Team, as a part of the Creative Research Program funded by the Ministry of Science, ICT and Future Planning, Republic of Korea.
Figure 1. Opal [left] and the nano glass bead arrangement structure within the opal [right]
Figure 2. Process chart of the photonic crystal micro-pattern formation based on photolithography
Figure 3. Opal structure [left] and inverted structure of the opal [right]
Figure 4. Photonic crystal micro-pattern in solid colors
Figure 5. Photonic crystal micro-pattern that reflects two different crystals (Red, Green) [left] and pixelated pattern of photonic crystal in three primary colors (Red, Green, Blue) [right] that is applicable to reflective displays
2014.05.14 View 11367 -
SPIE (The International Society for Optics and Photonics): Scattering Super-lens
The International Society for Optics and Photonics (SPIE), dedicated to advancing an interdisciplinary approach to the science and application of light, published online a short paper authored by a KAIST research team, Dr. Jung-Hoon Park and Professor YongKeun Park of Physics, introducing a new optical technology to observe sub-wavelength light by exploiting multiple light scattering in complex media.
For the article, please go to the link below:
SPIE: Nanotechnology
May 7th, 2014
"Scattering superlens" by Jung-Hoon Park and YongKeun Park
http://spie.org/x108298.xml
2014.05.14 View 6729 -
Professor Jae-Kyu Lee Elected to Head the Association for Information Systems
Jae Kyu Lee, HHI (Hyundai Heavy Industries, Co., Ltd.) Chair Professor, College of Business at KAIST, has been elected to lead the world major academic society, Association for Information Systems (AIS), from July 2015 to June 2016. Professor Lee will be the first Korean to serve the organization as president. From July 2014 to June 2015, he will serve as president-elect.
Currently, Professor Lee is the Director of EEWS (Energy, Environment, Water, and Sustainability) Research Center at KAIST, focusing on research and development in finding solutions to critical issues facing humanity. He also played a pivotal role in the conclusion of a memorandum of understanding between HHI and KAIST in June 2013 to establish HHI-KAIST EEWS Research Center within the KAIST campus.
The AIS is the premier professional association for individuals and organizations who lead the research, teaching, practice, and study of information systems worldwide.
2014.05.14 View 9153 -
Yong-Joon Park, doctoral student, receives the Korea Dow Chemical Award 2014
Yong-Joon Park, a Ph.D. candidate of Materials Science and Engineering at KAIST, received the Korea Dow Chemical Award 2014, a prestigious recognition of the year’s best paper produced by students in the field of chemistry and materials science.
The award ceremony took place on April 18, 2014 at Ilsan Kintex, Republic of Korea.
The Korea Dow Chemical Award is annually given by Korea Dow Chemical and the Korean Chemical Society to outstanding papers produced by graduate and postdoc students. This year, a total of nine papers were selected out of 148 papers submitted.
The title of Park’s paper is “The Development of 3D Nano-structure-based New Concept Super-elastic Materials.” This material could be used in flexible electronic devices such as displays and wearable computers.
2014.05.03 View 8109 -
Binding Regulatory Mechanism of Protein Biomolecules Revealed
Professor Hak-Sung Kim
A research team led by Professor Hak-Sung Kim of Biological Sciences, KAIST, and Dr. Mun-Hyeong Seo, KAIST, has revealed a regulatory mechanism that controls the binding affinity of protein’s biomolecules, which is crucial for the protein to recognize molecules and carry out functions within the body.
The research results were published in the April 24th online edition of Nature Communications.
The protein, represented by enzyme, antibody, or hormones, specifically recognizes a variety of biomolecules in all organisms and implements signaling or immune response to precisely adjust and maintain important biological processes. The protein binding affinity of biomolecules plays a crucial role in determining the duration of the bond between two molecules, and hence to determine and control the in-vivo function of proteins.
The researchers have noted that, during the process of proteins’ recognizing biomolecules, the protein binding affinity of biomolecules is closely linked not only to the size of non-covalent interaction between two molecules, but also to the unique kinetic properties of proteins.
To identify the basic mechanism that determines the protein binding affinity of biomolecules, Professor Kim and his research team have made mutation in the allosteric site of protein to create a variety of mutant proteins with the same chemical binding surface, but with the binding affinity vastly differing from 10 to 100 times. The allosteric site of the protein refers to a region which does not directly bind with biomolecules, but crucially influences the biomolecule recognition site.
Using real-time analysis at the single-molecule level of unique kinetic properties of the produced mutant proteins, the researchers were able to identify that the protein binding affinity of biomolecules is directly associated with the protein’s specific kinetic characteristics, its structure opening rate.
Also, by proving that unique characteristics of the protein can be changed at the allosteric site, instead of protein’s direct binding site with biomolecules, the researchers have demonstrated a new methodology of regulating the in-vivo function of proteins.
The researchers expect that these results will contribute greatly to a deeper understanding of protein’s nature that governs various life phenomena and help evaluate the proof of interpreting protein binding affinity of biomolecules from the perspective of protein kinetics.
Professor Kim said, “Until now, the protein binding affinity of biomolecules was determined by a direct interaction between two molecules. Our research has identified an important fact that the structure opening rate of proteins also plays a crucial role in determining their binding affinity.”
[Picture]
A correlation graph of opening rate (kopening) and binding affinity (kd) between protein’s stable, open state and its unstable, partially closed state.
2014.05.02 View 9344