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Discovery of New Therapeutic Targets for Alzheimer's Disease
A Korean research team headed by Professor Dae-Soo Kim of Biological Sciences at KAIST and Dr. Chang-Jun Lee from the Korea Institute of Science and Technology (KIST) successfully identified that reactive astrocytes, commonly observed in brains affected by Alzheimer’s disease, produce abnormal amounts of inhibitory neurotransmitter gamma-Aminobutyric acid (GABA) in reaction to the enzyme Monoamine oxidase B (Mao-B) and release GABA through the Bestrophin-1 channel to suppress the normal signal transmission of brain nerve cells.
By suppressing the GABA production or release from reactive astrocytes, the research team was able to restore the model mice's memory and learning impairment caused by Alzheimer’s disease. This discovery will allow the development of new drugs to treat Alzheimer’s and other related diseases.
The research result was published in the June 29, 2014 edition of Nature Medicine (Title: GABA from Reactive Astrocytes Impairs Memory in Mouse Models of Alzheimer’s Disease).
For details, please read the article below:
Technology News, July 10, 2014
"Discovery of New Drug Targets for Memory Impairment in Alzheimer’s Disease"
http://technews.tmcnet.com/news/2014/07/10/7917811.htm
2014.07.16 View 9321 -
Professor Kyu-Young Whang Receives Contributions Award from ACM SIGMOD
Kyu-Young Whang, Distinguished Professor of Computer Science at KAIST, was the recipient of the 2014 ACM SIGMOND Contributions Award.
Founded in 1947, the Association for Computing Machinery (ACM) is the world’s largest educational and scientific computing society, delivering resources that advance computing as a science and profession.
SIGMOD is the Association for Computing Machinery’s Special Interest Group on Management of Data, which specializes in large-scale data management problems and databases.
Since 1992, ACM SIGMOND has presented the contributions award to one scientist who has made significant contributions to the field of database systems through research funding, education, and professional services. So far, 23 people including Professor Whang have received the award.
Professor Whang was recognized for his key role in the growth of international conferences and journals in the field of databases such as The VLDB Journal (The International Journal on Very Large Data Bases), VLDB Endowment Inc., IEEE Technical Committee on Data Engineering, and Database Systems for Advanced Applications (DASFAA). IEEE stands for the Institute of Electrical and Electronics Engineering.
For the full list of ACM SIGMOND Contributions Award recipients, please go to
http://www.sigmod.org/sigmod-awards/sigmod-awards#contributions.
2014.07.15 View 9083 -
KAIST develops TransWall, a transparent touchable display wall
At a busy shopping mall, shoppers walk by store windows to find attractive items to purchase. Through the windows, shoppers can see the products displayed, but may have a hard time imagining doing something beyond just looking, such as touching the displayed items or communicating with sales assistants inside the store. With TransWall, however, window shopping could become more fun and real than ever before.
Woohun Lee, a professor of Industrial Design at KAIST, and his research team have recently developed TransWall, a two-sided, touchable, and transparent display wall that greatly enhances users' interpersonal experiences.
With an incorporated surface transducer, TransWall offers audio and vibrotactile feedback to the users. As a result, people can collaborate via a shared see-through display and communicate with one another by talking or even touching one another through the wall. A holographic screen film is inserted between the sheets of plexiglass, and beam projectors installed on each side of the wall project images that are reflected.
TransWall is touch-sensitive on both sides. Two users standing face-to-face on each side of the wall can touch the same spot at the same time without any physical interference. When this happens, TransWall provides the users with specific visual, acoustic, and vibrotactile experiences, allowing them to feel as if they are touching one another.
Professor Lee said, "TransWall concept enables people to see, hear, or even touch others through the wall while enjoying gaming and interpersonal communication. TransWall can be installed inside buildings, such as shopping centers, museums, and theme parks, for people to have an opportunity to collaborate even with strangers in a natural way."
He further added that "TransWall will be useful in places that require physical isolation for high security and safety, germ-free rooms in hospitals, for example." TransWall will allow patients to interact with family and friends without compromising medical safety.
TransWall was exhibited at the 2014 Conference on Computer-Human Interaction (CHI) held from April 26, 2014 to May 1, 2014 in Toronto, Canada.
YouTube Link:
http://www.youtube.com/watch?v=1QdYC_kOQ_w&list=PLXmuftxI6pTXuyjjrGFlcN5YFTKZinDhK
2014.07.15 View 7728 -
Professor Min Hyuk Kim Appointed an Associate Editor on ACM Transactions on Graphics
Professor Min Hyuk Kim of KAIST's Computer Science Department has been appointed an associate editor for a prestigious international journal in the field of graphics, ACM Transactions on Graphics (TOG).
Founded in 1947, the Association for Computing Machinery (ACM) is the world’s largest educational and scientific computing society, delivering knowledge that advances computing as a science and profession.
Published during the past 35 years, ACM TOG is a highly regarded, peer-reviewed scientific journal that aims to disseminate the latest findings of research in computer graphics. Professor Kim is the first Korean scholar to serve the journal as an editor.
Professor Kim’s responsibilities are many, and they include selecting appropriate reviewers for submitted manuscripts to be published in the journal and reporting the results of review process.
He said, “The appointment was a great honor, and I’m looking forward to having the opportunity to make further contributions to the advancement of the graphics field.”
Professor Kim has published numerous papers on computer graphics with a focus on research in 3D imaging spectroscopy and visual perception.
2014.07.14 View 10264 -
Opening of "Education Donation Center" for Knowledge Sharing
KAIST is a leader in knowledge-sharing services for the educationally underprivileged. KAIST held the opening ceremony of the Education Donation Center at its Munji Campus on July 4, 2014 and was appointed as a “2014 Chungcheong-Gangwon province model local education donation center” sponsored by the Education Ministry of Korea and Korea Foundation for the Advancement of Science and Creativity.
The Education Donation Center (EDC) will integrate programs run by the Chungcheong-Gangwon province education donation organizations and introduce them to local chapter organizations. The EDC will recommend new donation organizations to the organizations in need. To ensure efficient donation, the EDC will consult programs of donation organizations. The EDC will also suggest regionally suitable education donation programs. KAIST will provide three staff members, six graduate students, and one to manage the career counselor to the center.
Joo-Sung Lee of the Business & Technology Management Department is the professor in charge of the EDC. He explained, “The center is the medium between the newly participating education donation organizations and the demand organizations. I will invest every effort to provide high-quality educational benefits to educationally underprivileged people."
KAIST has also been running an education service group called ‘Midam Scholarship’, an online education donation group called ‘Chalk’, and science camp programs for youth to establish the sharing and collaboration culture of KAIST.
2014.07.10 View 9152 -
Professor Sang Ouk Kim receives the 2014 Prime Minister Award for Nano Research
Professor Sang Ouk Kim
Sang Ouk Kim, a professor of Materials Science and Engineering at KAIST, received the 2014 Prime Minister Award from the Korean government for his nano research. The award ceremony, Nano Korea 2014, was held on July 2, 2014 at Coex in Seoul, Korea.
Professor Kim was recognized for his research on the control of various shapes of ultra-fine nano-structures using molecular assembly with ductile materials, such as polymers and carbon nano materials, and for his contribution to the growth of the nano field in Korea.
He developed a new molecular assembly control technology, for the first time in the world, which produced large-scale, ultra-fine nanopatterns through controlling the molecular arrangement of block copolymers. Using this technology, he further created a new semiconductor nanotechnology to reinforce the existing lithographic process of semiconductor manufacturing.
In addition, Professor Kim has focused on making a new type of three-dimensional carbon nano-materials by assembling carbon nanotubes or graphene at the molecular level. Developing a new process to produce nano-materials through the chemical doping process of carbon materials, which can be widely applied to solar cells or energy devices, is one of his research interests as well.
Professor Kim has published a total of 124 papers in international journals, such as Nature, Science, Nature Materials, Nature Communications, Advanced Materials, and Nano Letters. He was recently invited by Advanced Materials to contribute a review article for its 25th anniversary issue.
Professor Kim received both the KAIST Academic Award and the 13th Young Scientist Award of Korea in 2010. Since March 2014, he has served as one of the chair professors of KAIST.
Most recently, he was selected as the Scientist of the Month in June 2014 by the Ministry of Science, ICT and Future Planning, Republic of Korea, and the National Research Foundation of Korea.
2014.07.08 View 9493 -
The ICISTS-KAIST International Conference from August 4-8, 2014 in KAIST Campus, Korea
"Does science lead progress?"
This thought-provoking question will be explored this summer with hundreds of university students gathered from all around the world at the campus of the Korea Advanced Institute of Science and Technology (KAIST), a leading science and technology university in Korea.
Established in 2005, the International Conference for Integration of Science, Technology and Society (ICISTS)-KAIST has been hosted every summer for Korean and international university students in Daejeon, Republic of Korea. The conference features distinguished speakers from academia, business, and public sectors and enables participants to exchange views, identify issues affecting science and society, and explore possible solutions.
The ICISTS-KAIST is the largest interdisciplinary conference in Asia. It is organized by undergraduate students of KAIST and promotes the idea of a science- and technology-integrated society through international cooperation of college students from diverse backgrounds. Last year alone, about 400 participants from 103 universities in 25 countries attended the conference.
Marking the 10th anniversary, the ICISTS-KAIST International Conference 2014 will scrutinize the fundamental aspect of scientific and technological progress versus social advancement under the theme of "Does Science Lead Progress?"
"We hope that the conference provides students with an interactive platform to look into some of the essential, yet easily neglected, questions such as the purpose of science and technology education in a broader context of social values," said Dong-Yeon Woo, President of Organizing Committee for the ICISTS-KAIST International Conference 2014.
Among keynote speakers are Langdon Winner, a professor of Science and Technology Studies at Rensselaer Polytechnic Institute, Stephen Hilgartner, an associate professor of Science and Technology Studies at Cornell University, and Steve Breyman, an associate professor of Science and Technology Studies at Rensselaer Polytechnic Institute.
Langdon Winner will speak about the fallacy of the public perception that technological innovation leads to social revolution (his presentation is entitled "The Myth of Innovation"). Stephen Hilgartner will present four aspects of the politics of vision in today's science and technology ("Science, Technology, and the Politics of Vision"), and Steve Breyman will talk about the origin of scientific deception, misrepresentation, and prevarication ("The Agnotology of Hydrofracking").
The conference lasts five days, beginning on August 4th through August 8th, 2014 at KAIST campus. For participation, regular online application opens until July 11, 2014 at http://www.icists.org.
2014.07.04 View 9846 -
Professor Haeng-Ki Lee appointed as "ICCES Distinguished Fellow"
Professor Haeng-Ki Lee
Professor Haeng-Ki Lee from the Department of Civil and Environmental Engineering at KAIST has been appointed as “Distinguished Fellow” and has also received the “Outstanding Research Award” at the International Conference on Computational & Experimental Engineering and Sciences (ICCES).
Founded in 1986, ICCES is regarded as one of the most prestigious international conferences in the field of computational mechanics and experimental engineering.
The Nominating Committee at ICCES recommends the appointment of a distinguished member who has made significant contributions to the development of computational mechanics and experimental engineering. Professor Lee was the first Korean who received such title. Furthermore, he was the recipient of the “Outstanding Research Award” presented by ICCES for his academic research on damage mechanics of complex systems.
Professor Lee is currently serving as the Head of the Department of Civil and Environmental Engineering at KAIST and the Director of BK Plus Agency, a Korean government’s research program. He received an award from the Minister of Science, ICT and Future Planning in 2013 for the promotion of science and technology.
2014.07.02 View 11574 -
A KAIST startup, YBrain, builds a wearable device to cure Alzheimer's
A group of KAIST graduates from the Departments of Bio and Brain Engineering, Computer Science, Materials Science Engineering, and Industrial Design created a startup called YBrain (http://ybrain.com/). YBrain develops a wearable neuroscience technology to treat or reduce the symptoms of degenerative brain diseases such as dementia and Alzheimer’s. Their recent technological developments were covered in e27, one of the leading blogs based in Singapore. The blog covers topics like the latest technology innovation, startups, and entrepreneurship in Asia. A news article follows below:
e27, June 24, 2014
“This wearable tech may be able to combat effects of Alzheimer’s”
http://e27.co/this-wearable-tech-may-be-able-combat-effects-of-alzheimers-20140624/
2014.06.25 View 12198 -
The First Demonstration of a Self-powered Cardiac Pacemaker
As the number of pacemakers implanted each year reaches into the millions worldwide, improving the lifespan of pacemaker batteries has been of great concern for developers and manufacturers. Currently, pacemaker batteries last seven years on average, requiring frequent replacements, which may pose patients to a potential risk involved in medical procedures.
A research team from the Korea Advanced Institute of Science and Technology (KAIST), headed by Professor Keon Jae Lee of the Department of Materials Science and Engineering at KAIST and Professor Boyoung Joung, M.D. of the Division of Cardiology at Severance Hospital of Yonsei University, has developed a self-powered artificial cardiac pacemaker that is operated semi-permanently by a flexible piezoelectric nanogenerator.
The artificial cardiac pacemaker is widely acknowledged as medical equipment that is integrated into the human body to regulate the heartbeats through electrical stimulation to contract the cardiac muscles of people who suffer from arrhythmia. However, repeated surgeries to replace pacemaker batteries have exposed elderly patients to health risks such as infections or severe bleeding during operations.
The team’s newly designed flexible piezoelectric nanogenerator directly stimulated a living rat’s heart using electrical energy converted from the small body movements of the rat. This technology could facilitate the use of self-powered flexible energy harvesters, not only prolonging the lifetime of cardiac pacemakers but also realizing real-time heart monitoring.
The research team fabricated high-performance flexible nanogenerators utilizing a bulk single-crystal PMN-PT thin film (iBULe Photonics). The harvested energy reached up to 8.2 V and 0.22 mA by bending and pushing motions, which were high enough values to directly stimulate the rat’s heart.
Professor Keon Jae Lee said:
“For clinical purposes, the current achievement will benefit the development of self-powered cardiac pacemakers as well as prevent heart attacks via the real-time diagnosis of heart arrhythmia. In addition, the flexible piezoelectric nanogenerator could also be utilized as an electrical source for various implantable medical devices.”
This research result was described in the April online issue of Advanced Materials (“Self-Powered Cardiac Pacemaker Enabled by Flexible Single Crystalline PMN-PT Piezoelectric Energy Harvester”: http://onlinelibrary.wiley.com/doi/10.1002/adma.201400562/abstract).
Youtube link: http://www.youtube.com/watch?v=ZWYT2cU_Mog&feature=youtu.be
Picture Caption: A self-powered cardiac pacemaker is enabled by a flexible piezoelectric energy harvester.
2014.06.25 View 16771 -
KAIST doctoral student wins prize at 2014 International Military Science and Technology Fair
Min-Kyu Yoo (far left), a doctoral student in the Department of Materials Science Engineering, KAIST, received a silver prize at the 2014 International Military Science and Technology Fair held from May 29 to June 1, 2014 at KINTEX, Ilsan City, Korea.
Yoo presented a paper on aluminum composite materials that were reinforced by carbon nanotubes. Carbon nanotubes reinforced aluminum composite materials have strong mechanical properties, and some nations have used them to manufacture battle tanks.
Aluminum generates hydrogen in an alkaline solution. Utilizing this property and the galvanic corrosion of carbon nanotubes and aluminums, Yoo developed a hydrogen energy system that is fueled with composite materials of carbon nanotube reinforced aluminum. He produced 5 kW electric power and maintained it 22 days using 10 kg of the composite materials for a proton exchange membrane fuel cell and its auxiliary power system.
Yoo’s research will alleviate the difficulty of transporting fuels during wartime and can be applied to the development of an auxiliary power system for next generation aircrafts and battle tanks.
2014.06.24 View 9115 -
Distinguished Professor Sang Yup Lee Attends World Economic Forum's Workshop
Sang Yup Lee, Distinguished Professor of Chemical and Biomolecular Engineering at KAIST was invited to attend the Technology Pioneer and Global Growth Company CEO Workshop hosted by the World Economic Forum (WEF) on June 19-20, 2014 in San Francisco. During the workshop, Professor Lee joined a discussion on “disruptive technologies” as a panelist.
Currently serving for the evaluation committee that selects technology pioneers for the workshop, during the discussion, Professor Lee identified important issues facing humanity, analyzed the issues through forecasting, and presented converging disruptive technologies that provide solutions to the problems. He also shared the “ten emerging technologies” announced by the Global Agenda Council on Emerging Technologies, WEF and the Korean government’s technology innovation strategies adopted to achieve its economic development policy called creative economy.
2014.06.22 View 8724