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Discovery of New Therapeutic Targets for Alzheimer's Disease
A Korean research team headed by Professor Dae-Soo Kim of Biological Sciences at KAIST and Dr. Chang-Jun Lee from the Korea Institute of Science and Technology (KIST) successfully identified that reactive astrocytes, commonly observed in brains affected by Alzheimer’s disease, produce abnormal amounts of inhibitory neurotransmitter gamma-Aminobutyric acid (GABA) in reaction to the enzyme Monoamine oxidase B (Mao-B) and release GABA through the Bestrophin-1 channel to suppress the normal signal transmission of brain nerve cells.
By suppressing the GABA production or release from reactive astrocytes, the research team was able to restore the model mice's memory and learning impairment caused by Alzheimer’s disease. This discovery will allow the development of new drugs to treat Alzheimer’s and other related diseases.
The research result was published in the June 29, 2014 edition of Nature Medicine (Title: GABA from Reactive Astrocytes Impairs Memory in Mouse Models of Alzheimer’s Disease).
For details, please read the article below:
Technology News, July 10, 2014
"Discovery of New Drug Targets for Memory Impairment in Alzheimer’s Disease"
http://technews.tmcnet.com/news/2014/07/10/7917811.htm
2014.07.16 View 9547 -
KAIST develops TransWall, a transparent touchable display wall
At a busy shopping mall, shoppers walk by store windows to find attractive items to purchase. Through the windows, shoppers can see the products displayed, but may have a hard time imagining doing something beyond just looking, such as touching the displayed items or communicating with sales assistants inside the store. With TransWall, however, window shopping could become more fun and real than ever before.
Woohun Lee, a professor of Industrial Design at KAIST, and his research team have recently developed TransWall, a two-sided, touchable, and transparent display wall that greatly enhances users' interpersonal experiences.
With an incorporated surface transducer, TransWall offers audio and vibrotactile feedback to the users. As a result, people can collaborate via a shared see-through display and communicate with one another by talking or even touching one another through the wall. A holographic screen film is inserted between the sheets of plexiglass, and beam projectors installed on each side of the wall project images that are reflected.
TransWall is touch-sensitive on both sides. Two users standing face-to-face on each side of the wall can touch the same spot at the same time without any physical interference. When this happens, TransWall provides the users with specific visual, acoustic, and vibrotactile experiences, allowing them to feel as if they are touching one another.
Professor Lee said, "TransWall concept enables people to see, hear, or even touch others through the wall while enjoying gaming and interpersonal communication. TransWall can be installed inside buildings, such as shopping centers, museums, and theme parks, for people to have an opportunity to collaborate even with strangers in a natural way."
He further added that "TransWall will be useful in places that require physical isolation for high security and safety, germ-free rooms in hospitals, for example." TransWall will allow patients to interact with family and friends without compromising medical safety.
TransWall was exhibited at the 2014 Conference on Computer-Human Interaction (CHI) held from April 26, 2014 to May 1, 2014 in Toronto, Canada.
YouTube Link:
http://www.youtube.com/watch?v=1QdYC_kOQ_w&list=PLXmuftxI6pTXuyjjrGFlcN5YFTKZinDhK
2014.07.15 View 7902 -
Professor Haeng-Ki Lee appointed as "ICCES Distinguished Fellow"
Professor Haeng-Ki Lee
Professor Haeng-Ki Lee from the Department of Civil and Environmental Engineering at KAIST has been appointed as “Distinguished Fellow” and has also received the “Outstanding Research Award” at the International Conference on Computational & Experimental Engineering and Sciences (ICCES).
Founded in 1986, ICCES is regarded as one of the most prestigious international conferences in the field of computational mechanics and experimental engineering.
The Nominating Committee at ICCES recommends the appointment of a distinguished member who has made significant contributions to the development of computational mechanics and experimental engineering. Professor Lee was the first Korean who received such title. Furthermore, he was the recipient of the “Outstanding Research Award” presented by ICCES for his academic research on damage mechanics of complex systems.
Professor Lee is currently serving as the Head of the Department of Civil and Environmental Engineering at KAIST and the Director of BK Plus Agency, a Korean government’s research program. He received an award from the Minister of Science, ICT and Future Planning in 2013 for the promotion of science and technology.
2014.07.02 View 11947 -
"KAIST Day" at the Korean Baseball League: Hanwha Eagles Home Game
KAIST is out to promote school spirit and to strengthen the communication with Daejeon citizens.
KAIST’s Graduate Student Union held “KAIST Day” by supporting a baseball game between the Lotte Giants and Hanwha Eagles, a home team of Daejeon City, on June 26, 2014 at Daejeon Baseball Stadium.
Marking the third KAIST Day this year, the event has been organized to provide graduate students with opportunities to leave their labs and enjoy a moment of relaxation, such as watching baseball games.
The event began with an opening ceremony, followed by the main baseball game. The KAIST cheering squad, ELKA, held a pregame performance to root for a home-team victory. KAIST President Steve Kang and Sin-Yeong Kim, a master’s student at KAIST, threw the first pitch to celebrate KAIST Day.
Picture below:
President Steve Kang, Mia Kang, and graduate students cheering at the Hanwha Eagles' home team baseball game on June 26, 2014 at Daejeon Baseball Stadium
2014.07.02 View 7610 -
JEROS, a jellyfish exterminating robot, appears in a US business and technology news
Business Insider, a US business and technology news website launched in 2006 and based in New York City, published a story about JEROS, a robot that disposes of ever-increasing jellyfish in the ocean.
JEROS was the brainchild of Professor Hyun Myung at the Department of Civil and Environmental Engineering, KAIST. It can shred almost one tons worth of jellyfish per hour.
For the story, please visit the following link:
Business Insider, June 24, 2014
“These Jellyfish-Killing Robots Could Save the Fishing Industry Billions Per Year”
http://www.businessinsider.com/jellyfish-killing-robot-2014-6
JEROS in action
2014.06.26 View 9359 -
Forbes Asia: 48 Heroes of Philanthropy
Mun-Sul Jeong
Hui-Jeong Park
Forbes Asia, an American business magazine covering the latest news on Asian markets, politics, business, and finance, announced the list of 48 philanthropists in the Asia-Pacific region in its July 21, 2014 issue.
Four Koreans made the list: Mun-Sul Jeong (a former chairman of KAIST's Board of Trustees), Hui-Jeong Park (a wife of the late Dr. Geun-Chul Ryu, a philanthropist who gave the funds to build the Sports Complex in KAIST campus), Yuna Kim (a former Olympics figure skater and a gold and silver medalist), and Nam-Kyu Min (the chairman of JK Group, a plastics and petrochemical products manufacturer).
Mun-Sul Jeong, the founder of Mirae Corp., a semiconductor equipment manufacturing company, donated $21 million to KAIST for brain science research this year. He also donated $235 million to KAIST in 2001 for convergence research in information and business technology.
Hui-Jeong Park, a former professor of nursing at Korea University, endowed a $100,000 scholarship fund for KAIST students in January 2014. Her late husband, Dr. Geun-Chul Ryu, contributed over $55 million in real estate to KAIST, allowing the university to have a new sports facility. He was an eminent doctor of Oriental medicine in Korea and also served as a professor at KAIST.
For more, please click on the link below:
Forbes Asia, July 21, 2014
“48 Heroes of Philanthropy”
http://www.forbes.com/sites/johnkoppisch/2014/06/25/48-heroes-of-philanthropy-3/
2014.06.26 View 9666 -
A KAIST startup, YBrain, builds a wearable device to cure Alzheimer's
A group of KAIST graduates from the Departments of Bio and Brain Engineering, Computer Science, Materials Science Engineering, and Industrial Design created a startup called YBrain (http://ybrain.com/). YBrain develops a wearable neuroscience technology to treat or reduce the symptoms of degenerative brain diseases such as dementia and Alzheimer’s. Their recent technological developments were covered in e27, one of the leading blogs based in Singapore. The blog covers topics like the latest technology innovation, startups, and entrepreneurship in Asia. A news article follows below:
e27, June 24, 2014
“This wearable tech may be able to combat effects of Alzheimer’s”
http://e27.co/this-wearable-tech-may-be-able-combat-effects-of-alzheimers-20140624/
2014.06.25 View 12538 -
Professor Won Do Heo on LED Light Technology for Controlling Proteins in Living Cells
With the newly developed LED technology, Professor Won Do Heo at the College of Life Science and Bioengineering, KAIST, was able to suppress cell migration and division when cells are exposed to LED light. This suggests a breakthrough to apply in future cancer cell research.
Professor Heo talked about the impact of his research in the following excerpt from a news article:
“We are already conducting research on the spread of cancer, as well as brain science in animal models with the Light-Activated Reversible Inhibition by Assembled Trap. I believe this technology will be a breakthrough in investigating cancer treatments and the function of neurons in a complex neural network, which existing technologies have not been able to do.”
From EE Times Europe, June 19, 2014
“LED Light Technology Controls Proteins in Living Cells”
http://www.ledlighting-eetimes.com/en/led-light-technology-controls-proteins-in-living-cells.html?cmp_id=7&news_id=222909336
2014.06.22 View 8168 -
KAIST's Center for Integrated Smart Sensors made a partnership with a Silicon Valley start-up
KAIST's Center for Integrated Smart Sensors (CISS) will implement a joint venture project with Dual Aperture, Inc., a leading digital camera provider based in Palo Alto, California. The two will work on the development of 3-D imaging technology.
CISS, headed by Professor Chong-Min Kyung of Electrical Engineering, KAIST, is dedicated to technological advancement by developing innovative devices, circuits, and smart sensors.
In its press release dated June 18, 2014, Dual Aperture, Inc. stated that “by combining top talents in engineering, the partnership will establish a groundbreaking smart sensor technology accessible on multiple platforms and devices.”
For details, a Fox news article follows below:
Dual Aperture, Inc., June 18, 2014
“Image technology leader and top research institute collaborate engineering resources to create world’s first-ever smart sensor technology”
http://www.fox14tv.com/story/25808022/dual-aperture-announces-joint-venture-with-kaists-center-for-integrated-smart-sensors
2014.06.19 View 9565 -
Professor Sang Ouk Kim Receives the "Scientist of the Month Award" from the Korean Government
Professor Sang Ouk Kim of the Department of Materials Science and Engineering, KAIST, received the Scientist of the Month Award in June 2014 for his development of a fundamental technology that allows free control of the properties of carbon-based materials.
Since June 1997, the Korean government has awarded monthly one scientist working in industry, universities, or research institutions to recognize his or her research achievements, as well as to promote science and technology.
Professor Kim implemented a technique known as doping, which has been used in ordinary semiconductor processes, to demonstrate the physical properties of carbon-based materials. Carbon nanotubes, graphene, and other carbon materials have superior mechanical and electrical properties and are regarded as next-generation materials. However, difficulty in controlling their qualities has made applications in various devices unfavorable. The doping technique in semiconductor production is to artificially introduce impurities into an extremely pure semiconductor for the purpose of modulating its electrical properties.
Profess Kim doped elements like nitrogen and boron to enable minute control of the physical properties of carbon-based materials and applied the technique to development of organic solar cells, organic light-emitting devices, and flexible memory. He also increased the application range by using a self-assembly method to change freely the structure of carbon-based materials.
Professor Kim has published 53 papers in renowned journals such as Advanced Materials and Nanoletters. He was rewarded further by being invited to write a review paper for the 25th anniversary special edition for Advanced Materials.
2014.06.19 View 10553 -
A KAIST graduate named one of seven Microsoft Research Faculty Fellows for 2014
Yong-Yeol Ahn, a professor of the School of Informatics and Computing, Indiana University Bloomington (IUB), has been selected as one of the seven winners for the Microsoft Research Faculty Fellowship 2014. He received his Ph.D. in 2008 from KAIST.
Each year, since 2005, Microsoft Research has recognized innovative, promising new faculty members in computer science from a number of research institutions to join the ranks of Microsoft Research Faculty Fellows. The winners are awarded $200,000 grants to further advance their research.
For details, below please see a press release issued by IUB on June 12, 2014.
IU Bloomington Newsroom
Press Release, June 12, 2014
IU informaticist Y.Y. Ahn named one of seven Microsoft Research Faculty Fellows
http://news.indiana.edu/releases/iu/2014/06/yy-ahn-microsoft-research-faculty-fellow.shtml
2014.06.15 View 8492 -
An Exploratory Study on Smartphone Abuse among College Students
Professor Uichin Lee
Professor Uichin Lee of the Department of Knowledge Service Engineering, KAIST, and his research team developed a system that automatically diagnoses the levels of smartphone addiction based on an analysis of smartphone use records.
Professor Lee investigated the usage patterns of 95 smartphone users (college students) by conducting surveys and interviews and collecting logged data. The research team divided participants into “risk” and “non-risk” groups based on a self-reported rating scale to evaluate their abuse of smartphones. As a result, 36 students were categorized as “high risk” and 59 were categorized as “low risk.”
The researchers collected over 50,000 hours of smartphone use encompassing power levels, screen, battery status, application use, internet use, calling, and texting.
The results showed that the “high risk” group used only 1~2 applications, focusing on mobile messengers (Kakotalk, etc.) and SNS (Facebook, etc.).
In addition, a relationship was found between alarm function and addiction levels. Users who set alarms for Kakaotalk messages and SNS comments used smartphones for an additional 38 minutes per day on average.
Results also showed that “high risk” students were on their smartphones for 4 hours and 13 minutes per day, 46 minutes longer than “low risk” students who used smartphones for 3 hours and 27 minutes. The difference was prevalent during 6 am and noon, and 6pm and midnight. In addition, “high risk” students accessed their smartphones 11.4 times more than “low risk” students.
Based on the collected data, Professor Lee developed an automatic system that distinguished users into “high risk” or “low risk” categories with 80% accuracy. The new system is expected to give an early diagnosis of addiction to smartphone users, thereby allowing for early treatment and intervention before the user becomes addicted.
Professor Lee commented that, "the conventional addiction analysis based on self-analysis surveys did not provide real-time data and were largely inaccurate. The new system overcomes these limitations through data science and personal big data analysis" and that he is "developing an application that monitors smartphone abuse."
Figure 1. Usage amount: overall and application-specific results
Figure 2. Usage frequency: overall and application-specific results
Figure 3. Overall diurnal usage time and frequency
2014.06.05 View 7946