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'Scientist-Engineer of the Month' for December: Professor Choi Joon Ho
Professor Choi Joon Ho (department of Biological Sciences) was made ‘Scientist-Engineer of December’ for his discovery of new gene (twenty-four) that helps biorhythm and proving that this gene helps control biorhythm.
Professor Choi published 100 dissertations over the past 25 years and made significant advancements in the field of molecular virus and neurobiology.
In 1995 Professor Choi uncovered the fact that the NS3 protein in C type hepatitis function as RNA helicase thereby opening the path to developing a cure for C type hepatitis; this is an international patent with Chiron corporation. The result was published in Biochemical and Biophysical Research Communications Journal and was the most domestically referred to dissertation in biological sciences in 1999.
In addition Professor Choi published in Nature magazine in 1999, a dissertation that uncovered the fact that the DNA of papillomar virus has another protein (hSNF5) that direct it apart from ordinary proteins.
In 2000~2005 Professor Choi published many dissertations in journals like Immunity, Cancer Research, Molecular and Cellular Biology, Oncogene, Journal of Virology, and etc.
Professor Choi screened over 10,000 species of pomace fly mutations and discovered the twenty-four gene that affects the biorhythm of pomace flies. He analyzed this gene further and found a new function that was different from known biorhythm mechanisms.
This research allowed a better understanding of biological clock of pomace flies and therefore was another step towards better understanding the control mechanism of human biological clock.
2012.01.31 View 9896 -
Seeing Inside Cells with Fiber Optics
Professor Jiho Park’s research team was successful in receiving minute optical signals from inside the cell using optical nano fibers.
Through the invention of this technology, we can now look inside cells in high resolution without the use of equipment such as endoscopes that damage cells. We will be able to study the biological phenomena within cells, and thus cure diseases more effectively.
Recently, ultra high resolution microscopes have been used to analyze incubated cells. However, because of the need for a very complex and large system, it had been impossible to monitor cells in the less transparent areas of the body in real time.
The research team created the wire with a semiconductor created with tin oxides to be only 100 nanometers in diameter (1nanometer= 1/1billion meters).
The nanowire is connected to the end of the optical fiber, and the light that comes through the optical fiber is transmitted to particular spots in the cell, and the optical signals from the cell are retrieved back from the cell as well
Together with this, based on the fact that nanowires do not damage cells, the research team covered the end of the wire with a photo reactive material and entered this into the cell. They were able to check that the material reacted to light and entered the cell when they transmitted light
Accordingly, this showed the possibilities of the use of this technology as a method of treatment to effectively transfer the medication into the cells.
Prof. Jiho Park stated that “in this research, we only used cells incubated outside the human body, but soon we will use this technology to stimulate and control cells within the body in a minute scale” as well as that “soon, we will be able to study the biological phenomena inside a cell to study diseases and apply this to cure them more effectively”.
This research result has been published in the online publication of ‘Nature Nanotechnology’ on December 18.
This study was done through the cooperation of various schools. Besides Prof. Jiho Park, Prof. Seungman Yang from the Biochemistry department, and Doctor Chuljoon Huh from KAIST, Prof. Yeonho Choi from Biomedical Science department of Korea University, Professor Peidon Yang and Doctor Ruoxue Yan from UC Berkeley’s chemistry department, and Luke Lee from UC Berkeley’s bioengineering department participated in the project.
2012.01.31 View 10137
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KAIST Ph.D Mihyun Jang Employed as Professor at Technische Universitat Graz
A Ph.D purely from Korea has been employed as a professor at Technische Universitat Graz.
This is the news of Prof.Mihyun Kang (39) who has graduated from KAIST’s mathematics department. Prof.Kang has transferred on January 2012.
KAIST explained that “it’s the first time for a mathematics Ph.D from Korea has been employed abroad.”
Technische Universitat Graz of Australia is ranked the top third university within the country. It is a global university with 1,700 students from 78 different countries out of its 11,000 students.
Prof. Kang researched mainly theories of combination including random graphing theories, analytical combination theories, and probabilistic combination theories. She has been employed as a lifetime professor through open recruitment where she competed with others through academic debates and interviews.
Technische Universitat Graz valued Prof. Kang’s research highly made her the department head of the ‘Optimization and Discrete Mathematics department’ to create an environment where she could continuously research.
Prof. Kang graduated from Jeju university majoring math educations and did her graduate studies in KAIST. She is a purely ‘Korean’ Ph.D. After her studies, she worked for Germany’s Humboldt University and Freie Universitat Berlin. In 2007, she was able to be employed as a professor in Germany, and in 2008, she was chosen as a Heisenberg fellow.
Prof. Kang who had her research achievements recognized in Germany and Austria was also offered seat as professor in Ludwig Masximilan University of Germany and Alpenadria University in Austria, but chose Technische Universitat Graz.
2012.01.31 View 11574
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Professor Jang Soon Heung Appointed International Consultant of the Fukushima Nuclear Disaster Task Force
The Japanese government appointed Professor Jang Soon Heung (department of Nuclear and Quantum Engineering) as the International Consultant to the Fukushima Nuclear Disaster Task Force.
Professor Hatamura Yotaro of the Tokyo University is the head of the task force and is tasked with finding out the cause and extent of damage of the disaster and minimize social cost and expansion of damage along with prevent a similar disaster from occurring.
The International Consultants will independently advise and look over the findings of the task force.
The members include: Professor Jang Soon Heung (Professor of KAIST), Richard A. Meserve (Carnegie Research Center Director/Former Chairman of Nuclear Regulatory Commission), Andre-Claude Lacoste (Chairman of French Nuclear Safety Regulatory Commission), and Lars-Eirk Holm (Secretary General of Sweden Health and Welfare).
2012.01.31 View 8805
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Ten Breakthroughs of the Year 2011 by Science
Porous Zeolite Crytals
Science, an internationally renowned scientific journal based in the US, has recently released a special issue of “Breakthrough of the Year, 2011,” dated December 23, 2011. In the issue, the journal introduces ten most important research breakthroughs made this year, and Professor Ryong Ryoo, Department of Chemistry at KAIST, was one of the scientists behind such notable advancements in 2011. Professor Ryoo has been highly regarded internationally for his research on the development of synthetic version of zeolites, a family of porous minerals that is widely used for products such as laundry detergents, cat litters, etc. Below is the article from Science, stating the zeolite research:
For Science’s “Breakthrough of the Year, 2011”, please go to:
http://www.sciencemag.org/site/special/btoy2011/
[Excerpt from the December 23, 2011 Issue of Science]
Industrial Molecules, Tailor-Made
If you ever doubt that chemistry is still a creative endeavor, just look at zeolites. This family of porous minerals was first discovered in 1756. They"re formed from different arrangements of aluminum, silicon, and oxygen atoms that crystallize into holey structures pocked with a perfect arrangement of pores. Over the past 250 years, 40 natural zeolites have been discovered, and chemists have chipped in roughly 150 more synthetic versions.
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Porous zeolite crystals are widely used as filters and catalysts. This year, researchers found new ways to tailor the size of their pores and create thinner, cheaper membranes.
CREDIT: K. VAROON ET AL., SCIENCE334, 6052 (7 OCTOBER 2001)
This abundance isn"t just for show. Three million tons of zeolites are produced every year for use in laundry detergents, cat litter, and many other products. But zeolites really strut their stuff in two uses: as catalysts and molecular sieves. Oil refineries use zeolite catalysts to break down long hydrocarbon chains in oil into the shorter, volatile hydrocarbons in gasoline. And the minerals" small, regularly arranged pores make them ideal filters for purifying everything from the air on spaceships to the contaminated water around the nuclear reactors destroyed earlier this year in Fukushima, Japan.
Zeolites have their limitations, though. Their pores are almost universally tiny, making it tough to use them as catalysts for large molecules. And they"re difficult to form into ultrathin membranes, which researchers would like to do to enable cheaper separations. But progress by numerous teams on zeolite synthesis this year gave this “mature” area of chemistry new life.
Researchers in South Korea crafted a family of zeolites in which the usual network of small pores is surrounded by walls holed with larger voids. That combination of large and small pores should lead to catalysts for numerous large organic molecules.
Labs in Spain and China produced related large- and small-pore zeolites by using a combination of inorganic and organic materials to guide the structures as they formed.
Meanwhile, researchers in France and Germany discovered that, by carefully controlling growth conditions, they could form a large-pore zeolite without the need for the expensive organic compounds typically used to guide their architecture as they grow. The advance opens the way for cheaper catalysts. In yet another lab, researchers in Minnesota came up with a new route for making ultrathin zeolite membranes, which are likely to be useful as a wide variety of chemically selective filters.
This surge of molecular wizardry provides a vivid reminder that the creativity of chemists keeps their field ever young.
Related References and Web Sites
2011.12.23 View 12627 -
President Suh Nam Pyo meets a student who saved a person's life
President Nam-Pyo Suh visited Yo-Seop Kim (a junior from the Department of Materials Science and Engineering) at a hospital who was hurt while helping out a citizen in a dangerous situation. Nerves of his right arm were damaged as a result of the injury.
President Suh praised Yo-Seop’s act by saying that he had demonstrated true courage as a member of KAIST and relayed his sincere gratitude in performing the good deed of saving a life on behalf of KAIST and urged him to focus on rehabilitation. Wishing Yo-Seop to recover quickly and continue on living with a warm perspective of life, the president promised that the university would seek ways to provide him with the necessary assistance in his getting back to normal ife.
Yo-Seop Kim commented that the scar was an honorable and proud thing, humbly acknowledging, “Anybody in my situation would have done the same thing.” He further said that he would study harder to realize his dream after being discharged from the hospital.
Yo-Seop Kim was stabbed on the back of his hand whilst trying to block an unknown man from stabbing another person in a quarrel at Suwon Station on 25th of November. He received a wound across the back of his hand and consequently, his nerve was severed.
The story of Yo-Seop was posted on the KAIST Online Bulletin System from the 29th of November and registered 4,800 hits and words of encouragement and applause were written on the post.
Since the assailant was not applied to the national health insurance, Yo-Seop was having a difficult time paying the necessary surgery and insurance fees. President Suh instructed the university to find methods of helping him through various channels.
KAIST will be providing Yo-Seop with a portion of the surgery fees and rehabilitation at the KAIST Clinic after he is discharged from the hospital.
2011.12.13 View 10191 -
The Hindu, "Use of microalgae helps in controlling pollution," December 8, 2011
The Hindu, an Indian newspaper, reported on December 8, 2011 a research work by Professor Ji-Won Yang from the Department of Chemical and Biomolecular Engineering. For the news article, please go to the link at http://www.thehindu.com/sci-tech/energy-and-environment/article2695634.ece?homepage=true.
The Hindu, December 8, 2011
Use of microalgae helps in controlling pollution
By N. Gopal Raj
2011.12.12 View 9889
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Interview with the president of Hong Kong University of Science and Technology
The president of Hong Kong University of Science and Technology (HKUST), Dr. Tony Chan, who is also a member of KAIST’s President Advisory Council (PAC), had an interview with the Korea Times, November 16, 2011 and shared his thoughts on some fundamental essentials that make a good science and technology university. He visited KAIST Campus on November 10th and had a meeting with students as part of the university’s mentor program between PAC members and the students. For the interview, please visit the link below: http://www.koreatimes.co.kr/www/news/special/2011/11/181_98928.html
2011.11.18 View 11218
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Professor Son Hoon received "Structural Health Monitoring Person of the Year Award."
Professor Son Hoon (42) of the Department of Civil and Environmental Engineering received the “Structural Health Monitoring Person of the Year Award” at an international workshop on structural health monitoring held in Stanford University.
The award is given by the editor and advisors of prestigious international magazine, “Journal of Structural Health Monitoring,” to a researcher with the best research record in a year. Professor Son has published 42 SCI level dissertations, registered 17 patents both domestically and internationally, and presented over 100 papers in international journals, for which he was recognized with the award. Professor Son is the first Korean who receives this award.
One of the most significant achievements by Professor Son was “reference-free damage diagnosis” that he had developed in 2007. The diagnosis allows for the detection of wear and tear of a structure without having to use the foundation signal from the initial stages of the structure. The diagnosis contributed greatly in increasing the reliability of the signal information received from smart sensors attached to the structure by eliminating the environmental impact like temperature.
Professor Son is currently working on green energy structural health monitoring system development related projects. His current work deals with airplanes, bridges, nuclear facilities, high speed railways, wind turbines, and etc. in cooperation with Boeing, United States Air Force Research Institute, Korea Research Foundation, Ministry of Defense Research Institute, Korea Expressway Corporation, POSCO, and etc.
In addition, Professor Son successfully adopted a local monitoring method using smart piezoelectric sensors on a bridge in New Jersey as part of the Long Term Bridge Performance Program initiated by the National Highway Bureau. The success was even introduced in New Jersey’s public TV and newspaper agencies.
Professor Son was given tenure at a record age of 39 in 2008 and received numerous awards given out by the Ministry of Education and Science and international organizations like the ‘Edward M Curtis’ Professor Award from Purdue University.
2011.10.10 View 11201 -
Professor Choi Chul Hui appointed as editor-in-chief of Nanobiosensors in a disease diagnosis magazine
Professor Choi Chul Hui of the Department of Biological and Brain Engineering has been appointed the editor-in-chief of Nanobiosensors, an international medical magazine that concentrates on disease diagnosis.
As the editor-in-chief, Professor Choi will be involved in dissertation evaluations and overall direction of the magazine.
Professor Choi is one of the leading authorities in the field of clinical medicine and has published 60 SCI level dissertations in the fields of cell biology, computational biology, and bio-optics.
He is also the executive director of the KAIST BioImaging Research Center, and his research lab focuses on cell signals and bio imaging. Professor Choi is researching the generation process of degenerative diseases like arteriosclerosis by taking a multidisciplinary approach.
Professor Choi has recently developed a new bio imaging technique that allows for the measurement of perfusion and a new technology for the drug delivery to nerves using ultra short wavelength laser beams.
2011.10.10 View 10948 -
Cancer detection from an implantable, flexible LED
Professor Keon Jae Lee
A KAIST research team has developed a new type of biocompatible and bendable GaN LED biosensor.
Daejeon, the Republic of Korea, August 8, 2011—Can a flexible LED conformably placed on the human heart, situated on the corrugated surface of the human brain, or rolled upon the blood vessels, diagnose or even treat various diseases? These things might be a reality in the near future.
The team of Professor Keon Jae Lee (Department of Materials Science and Engineering, KAIST) has developed a new concept: a biocompatible, flexible Gallium Nitride (GaN) LED that can detect prostate cancer.
GaN LED, a highly efficient light emitting device, has been commercialized in LED TVs and in the lighting industry. Until now, it has been difficult to use this semiconductor material to fabricate flexible electronic systems due to its brittleness. The research team, however, has succeeded in developing a highly efficient, flexible GaN LED and in detecting cancer using a flexible LED biosensor.
Prof. Lee was involved in the first co-invention of "High Performance Flexible Single Crystal GaN" during his PhD course at the University of Illinois at Urbana-Champaign (UIUC). This flexible GaN LED biosensor utilized a similar protocol to transfer thin GaN LED films onto flexible substrates, followed by a biocompatible packaging process; the system’s overall potential for use in implantable biomedical applications was demonstrated.
Professor John Roger (Department of Materials Science and Engineering, UIUC) said,
“Bio-integrated LEDs represent an exciting, new technology with strong potential to address important challenges in human health. This present work represents a very nice contribution to this emerging field.”
This paper was published in the online issue of Nano Energy Elsevier Journal (Editor, Prof. Zhong Lin Wang) dated September 16, 2011.
Flexible GaN LED produces blue light.
2011.09.20 View 12096 -
Professor Lee Sang Yeop Nominated the Chairman of Emerging Technologies Global Agenda Council of the World Economic Forum
Professor Lee Sang Yeop, Dean of College Life Science & Bioengineering, was appointed as the chairman of the Emerging Technologies Global Agenda Council of the World Economic Forum.
He will be in office till the 31st of August 2012, exactly 1 year from the date of his appointment.
The World Economic Forum (WEF) is a ‘think tank’ consisting of world leaders in various fields like economics, politics, and policies and has created the ‘Global Agenda Council’ to solve the problems mankind faces in achieving environmentally sustainable growth and suggest a collective vision and strategy.
The committee to be chaired by Professor Lee (Emerging Technologies Global Agenda Council) will discuss the direction in which the fields of biological engineering, nanotechnology, and IT (information technology) should develop and discuss the possible impact these fields will have on the society.
Professor Lee commented that, “I am extremely happy to be appointed as the chair of the Emerging Technologies Global Agenda Council at the World Economic Forum which is a gathering of world class leaders” and that “it is a great opportunity to spread Korea’s success and lessons in the advancement of science and technology.”
Professor Lee is the creator of the field of system metabolism engineering and is making great strides in manipulating the microorganism’s metabolic pathways on a systems scale to make changing chemicals derived from oil into eco-friendly and bio-based products.
2011.09.20 View 9906