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A New Way to Look at MOFs
An international research team composed of researchers from KAIST (led by Professors Osamu Terasaki and Jeung Ku Kang at the Graduate School of Energy, Environment, Water and Sustainability) and other universities, including UC Berkeley, has recently published research results on the adsorption process of metal-organic frameworks (MOFs) in Nature (November 9, 2015).
MOFs are porous three-dimensional crystals with a high internal surface area, which have a wide range of applications involving adsorption such as hydrogen, methane, or carbon dioxide storage. In the paper entitled “Extra Adsorption and Adsorbate Superlattice Formation in Metal-organic Frameworks,” the research team described their observation of a very specific interpore interaction process in MOFs.
For additional information, please see:
A New Way to Look at MOFs
International study challenges prevailing view on how metal organic frameworks store gases
EurekAlert, November 9, 2015
http://www.eurekalert.org/pub_releases/2015-11/dbnl-anw110915.php
(Courtesy of the US Department of Energy and Lawrence Berkeley National Laboratory news release)
2015.11.13 View 9333 -
Dual Degree Agreement on the Master's Program of Electrical Engineering with the Technical University of Denmark
KAIST and the Technical University of Denmark (DTU) established a joint degree program for master’s students in electrical engineering. The agreement, made on October 22, 2015, will allow master students from both universities to study for one year at each institution.
For details, go to the DTU news: http://www.dtu.dk/english/News/Nyhed?id=9e7b91e5-1719-4421-8cc2-5e3fe7d605d7
2015.11.03 View 4364 -
Partnership with École Centrale Paris
Courtesy of École Centrale Paris News: http://www.ecp.fr/lang/en/home/news?actuID=48892
Strengthening of the partnership betwenn CentraleSupélec and KAIST University, South Korea
The two institutions signed a new agreement.
Hervé Biausser (left in the picture), Director of CentraleSupélec, has met Sung-Mo Steve Kang (right in the picture), the President of the Korea Advanced Institute of Science and Technology (KAIST). They signed an agreement aiming to strengthen the partnership between the two institutions concerning research and higher education.
CentraleSupélec and KAIST have cooperated since 2010 on research projects in the context of the Erasmus Mundus BEAM and EASED programs, which are coordinated by CentraleSupélec.
The next step is now the application of graduate academic mobility in the common fields of excellency of the institutions: energy, electronic, physics and mathematics.
2015.11.02 View 7052 -
KAIST's College of Business Places Fourth in the 2015 Better World MBA Ranking
The Corporate Knights, a business and society magazine based in Canada, released the results of the 2015 Better World MBA Ranking on October 8, 2015.
KAIST’s business school ranked fourth globally and, number one in Asia, according to the list.
The 2015 Corporate Knights Better World MBA Ranking included a total of 121 schools; York University’s Schulich School of Business of Canada took first place.
The rankings were based on three criteria: the number of curricula (core and required courses) dedicated to sustainability, the number of research institutions and centers at the business school, and the volume of faculty research focused on better world topics such as sustainable finance, clean energy, or gender diversity.
The Better World MBA Ranking aims to identify business schools that best equip graduates who seek to change the world for the better by offering students opportunities to learn how to integrate social and environmental factors in their understanding of management functions via core MBA courses, faculty expertise, and research centers.
Dean Dong-Seok Kim of the College of Business at KAIST said,
“For years, our school has introduced a wide range of programs and research initiatives that address important social needs and issues. As part of this effort, we created the Graduate School of Green Growth and MBA for Social Entrepreneurship back in 2013. I believe that these endeavors played a favorable role in our receiving high scores in the ranking.”
KAIST’s Graduate School of Green Growth previously ranked sixth in the world’s top Green MBA School list published by Corporate Knights.
For the 2015 Better World MBA Ranking, go to
http://www.corporateknights.com/reports/2015-global-sustainable-mba/11153-14442629/.
2015.10.12 View 6548 -
Yang-Hann Kim named recipient of the Rossing Prize in Acoustics Education by the Acoustical Society of America
Courtesy of the Acoustical Society of America (ASA)
Press release issued by ASA on October 8, 2015:
Yang-Hann Kim named recipient of the Rossing Prize in Acoustics Education by the Acoustical Society of America
Melville (NY), 8 October 2015—Yang-Hann Kim, Professor at KAIST (Korea Advanced Institute of Science and Technology), Daejeon, has been named recipient of the Acoustical Society of America (ASA) Rossing Prize in Acoustics Education. The Rossing Prize is awarded to an individual who has made significant contributions toward furthering acoustics education through distinguished teaching, creation of educational materials, textbook writing and other activities. The Prize will be presented at the 170th meeting of the ASA on 4 November 2015 in Jacksonville, Florida.
“It is my great honor to receive the Rossing Prize, which has been given to outstanding scholar members of ASA since 2003. I never dreamed to be one of them.” said Kim. “I must express my deep respect and love to my friend Thomas Rossing: I have known him more than 20 years, always respect what he has done for teaching, writing books, and pioneering work in musical acoustics.”
Yang-Hann Kim is a Fellow of the Acoustical Society of America. He received a Ph.D. from the Massachusetts Institute of Technology. His main research interests in acoustics began with “sound visualization” resulted in the development of the “sound camera” which makes any sound visible instantly. Then he moved to “sound manipulation.” Using his manipulation technology, one can move any sound in space and time, positioning sound, and can create a private sound zone. Sound Visualization and Manipulation, (Wiley, 2013), summarizes these two fields. Dr. Kim’s textbook, Sound Propagation: An Impedance Based Approach (John Wiley and Sons, 2010), is well acknowledged by the associated professional communities as one of best acoustics textbooks. Using his teaching experience at KAIST, he created a YouTube lecture on acoustics and vibration which is also available in MOOC (Massive Open Online Course). He has also presented lectures to over 500 engineers and technicians for the past 30 years.
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The Acoustical Society of America (ASA) is the premier international scientific society in acoustics devoted to the science and technology of sound. Its 7000 members worldwide represent a broad spectrum of the study of acoustics. ASA publications include the Journal of the Acoustical Society of America—the world’s leading journal on acoustics, Acoustics Today magazine, books, and standards on acoustics. The Society also holds two major scientific meetings per year. For more information about the Society visit our website, www.acousticalsociety.org.
2015.10.06 View 12032 -
KAIST Makes a List of Top Ten Most Innovative Universities around the World
Reuters News released a list of the World’s Top 100 Most Innovative Universities on September 15, 2015.
Nine of the top ten universities on the list were American institutions. KAIST took tenth place, the only non-American and Asian university to do so.
Stanford University ranked first, followed by the Massachusetts Institute of Technology (MIT) in second, and Harvard University in third.
The inaugural Reuters Top 100 survey based its rankings on ten criteria: patent volume, patent successes, global patents, patent citations, patent citation impact, percent of patents cited, patent to article citation impact, industry article citation impact, percent of industry collaborative articles, and the total number of science papers.
Japan had nine universities in the survey, more than all countries except for the United States. South Korea has a total of eight universities on the list including Pohang University of Science and Technology, Seoul National University, Yonsei University, and Hanyang University.
For the full details of the survey, see
http://www.reuters.com/article/2015/09/15/idUSL1N11K16Q20150915.
2015.09.23 View 5208 -
KAIST Ranks 13th in Engineering and Technology and 43rd in Overall Ranking in the 2015 QS World University Rankings
For the first time, the university has broken into the ranks of top 50 global universities since the first release of the rankings in 2004. The 2015 QS World University Rankings were released on September 15, 2015. Overall, KAIST ranked 43rd, advancing eight steps up from last year’s results. Its engineering and technology rank now places it 13th in the global rankings, but it is first in Korea's rankings. Both represent the highest record KAIST has ever attained since the QS Rankings began in 2004. The QS Rankings uses six performance indicators to assess universities’ global reputation, research impact, staffing levels, and international complexion. The indicators are: academic reputation (40%), employer reputation (10%), student-to-faculty ratio (20%), number of citations per faculty publications (20%), international to domestic faculty ratio (5%), and international to domestic student ratio (5%). The Massachusetts Institute of Technology (MIT) topped the 2015 list, with Harvard University coming in second place. The University of Cambridge and Stanford University jointly ranked third. For details on the 2015 QS World University Rankings, see http://www.topuniversities.com/university-rankings-articles/world-university-rankings/qs-world-university-rankings-201516-out-now.
2015.09.17 View 6147 -
KAIST to Hold a Colloquium on the Internet of Things and Open Stack
With the support of the Ministry of Science, ICT, and Future Planning of Korea, KAIST hosted a colloquium on the Internet of Things (IoT) and Open Stack at the KAIST Research Center for Global Cooperation located in Pangyo. The upcoming event was organized to provide an overview of the technological trends to IT companies and foster their success in the global market.
The colloquium invited numerous field-experts as speakers and discussed the influence of IoT and OpenStack on the small- and medium-sized companies in Korea.
Professor Gwan-Hoo Lee from the American University joined as a speaker and shared his insights of how IoT would change the global business environment. He introduced various business models developed by Microsoft, Intel, Apple, Google, and Cisco and discussed how Korean companies could utilize the existing tools and strategy to succeed in the global market. His talk focused specifically on the importance of overseas partnerships and technology stack analysis.
President Hyun-Jung Jang from the Korean OpenStack Community also gave a speech on global partnership through OpenStack. He discussed the future trends of OpenStack and why companies should invest in the field.
KAIST used the event as an opportunity to provide information to domestic companies that are interested in building partnerships with overseas companies and in developing new IoT and OpenStack technology.
More information about the event can be provided online at www.ictc.or.kr.
2015.09.11 View 6615 -
KAIST's Mathematician Reveals the Mechanism for Sustaining Biological Rhythms
Our bodies have a variety of biological clocks that follow rhythms or oscillations with periods ranging from seconds to days. For example, our hearts beat every second, and cells divide periodically. The circadian clock located in the hypothalamus generates twenty-four hour rhythms, timing our sleep and hormone release. How do these biological clocks or circuits generate and sustain the stable rhythms that are essential to life?
Jae Kyoung Kim, who is an assistant professor in the Department of Mathematical Sciences at KAIST, has predicted how these biological circuits generate rhythms and control their robustness, utilizing mathematical modeling based on differential equations and stochastic parameter sampling. Based on his prediction, using synthetic biology, a research team headed by Matthew Bennett of Rice University constructed a novel biological circuit that spans two genetically engineered strains of bacteria, one serves as an activator and the other as a repressor to regulate gene expression across multiple cell types, and found that the circuit generates surprisingly robust rhythms under various conditions.
The results of the research conducted in collaboration with KAIST (Korea Institute of Science and Technology), Rice University, and the University of Houston were published in Science (August 28, 2015 issue). The title of the paper is "Emergent Genetic Oscillations in a Synthetic Microbial Consortium" .
The top-down research approach, which focuses on identifying the components of biological circuits, limits our understanding of the mechanisms in which the circuits generate rhythms. Synthetic biology, a rapidly growing field at the interface of biosciences and engineering, however, uses a bottom-up approach.
Synthetic biologists can create complex circuits out of simpler components, and some of these new genetic circuits are capable of fluctuation to regulate gene production. In the same way that electrical engineers understand how an electrical circuit works as they construct batteries, resistors, and wires, synthetic biologists can understand better about biological circuits if they put them together using genes and proteins. However, due to the complexity of biological systems, both experiments and mathematical modeling need to be applied hand in hand to design these biological circuits and understand their function.
In this research, an interdisciplinary approach proved that a synthetic intercellular singling circuit generates robust rhythms to create a cooperative microbial system. Specifically, Kim's mathematical analysis suggested, and experiments confirmed, that the presence of negative feedback loops in addition to a core transcriptional negative feedback loop can explain the robustness of rhythms in this system. This result provides important clues about the fundamental mechanism of robust rhythm generation in biological systems.
Furthermore, rather than constructing the entire circuit inside a single bacterial strain, the circuit was split among two strains of Escherichia coli bacterium. When the strains were grown together, the bacteria exchanged information, completing the circuit. Thus, this research also shows how, by regulating individual cells within the system, complex biological systems can be controlled, which in turn influences each other (e.g., the gut microbiome in humans).
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Ye Chen, a graduate student in Bennett's laboratory at Rice University, and Jae Kyoung Kim, an assistant professor at KAIST and a former postdoctoral fellow at Ohio State University, are the lead authors of the paper. The co-authors are Rice graduate student Andrew Hirning and Krešimir Josic?, a professor of mathematics at the University of Houston. Bennett is the Assistant Professor of the Biochemistry and Cell Biology Department at Rice University.
About the researcher: While Jae Kyoung Kim is a mathematician, he has also solved various biological puzzles in collaboration with various experimental laboratories of Matthew Bennett at Rice University, David Virshup at Duke and the National University of Singapore, Carla Finkielstein at Virginia Polytechnic Institute and State University, Choo-Gon Lee at the Florida State University, Seung-Hee Yoo at the Medical School of the University of Texas, Toru Takumi at RIKEN Brain Science Institute, and Travis Wager at Pfizer Inc. He has used non-linear dynamics and stochastic analysis to understand the function of biochemical networks in biological systems. In particular, he is interested in mechanisms generating and regulating biological rhythms.
Picture 1: This schematic image is the design of a biological circuit between two strains of bacteria and the part of differential equations used to understand the function of the biological circuit.
Picture 2: The core transcriptional negative feedback loop and additional negative feedback loop in the biological circuit (picture 1) generate robust rhythms. The snapshots correspond the red dots in the time series graph.
2015.08.31 View 9741 -
Nature Biotechnology Nominates Sang Yup Lee of KAIST for Top 20 Translational Researchers of 2014
Nature Biotechnology, recognized as the most prestigious journal in the field of biotechnology, has released today its list of the Top 20 Translational Researchers of 2014. Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering at KAIST (Korea Advanced Institute of Science and Technology) ranked seventh in the list. He is the only Asian researcher listed.
The journal, in partnership with IP Checkups, a patent analytics firm, presents an annual ranking of researchers based on their paper and patent output. The list includes, among others, each researcher’s most-cited patent in the past five years and their H index, a measurement to evaluate the impact of a researcher’s published work utilizing citation analysis. (More details can be found at http://www.nature.com/bioent/2015/150801/full/bioe.2015.9.html.)
American institutions made up the majority of the list, with 18 universities and research institutes, and the remainder was filled by KAIST in Korea and the Commonwealth Scientific and Industrial Research Organization (CSIRO) in Australia.
Globally known as a leading researcher in systems metabolic engineering, Professor Lee has published more than 500 journal papers and 580 patents. He has received many awards, including the Citation Classic Award, Elmer Gaden Award, Merck Metabolic Engineering Award, ACS Marvin Johnson Award, SIMB Charles Thom Award, POSCO TJ Park Prize, Amgen Biochemical Engineering Award, and the Ho Am Prize in Engineering.
2015.08.27 View 13435 -
'Engineered Bacterium Produces 1,3-Diaminopropane'
A research team led by Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering at KAIST reported, for the first time, the production of 1,3-diaminopropane via fermentation of an engineered bacterium.
1,3-Diaminopropane is a three carbon diamine, which has a wide range of industrial applications including epoxy resin and cross-linking agents, as well as precursors for pharmaceuticals, agrochemicals, and organic chemicals. It can also be polymerized with dicarboxylic acids to make polyamides (nylons) for use as engineering plastics, medical materials, and adhesives.
Traditionally, 1,3-diaminopropane is derived from petroleum-based processes. In effort to address critical problems such as the depletion of petroleum and environmental issues inherent to the petroleum-based processes, the research team has developed an Escherichia coli (E. coli) strain capable of producing 1,3-diaminopropane. Using this technology, 1,3-diaminopropane can now be produced from renewable biomass instead of petroleum.
E. coli as found in nature is unable to produce 1,3-diaminopropane. Metabolic engineering, a technology to transform microorganisms into highly efficient microbial cell factories capable of producing chemical compounds of interest, was utilized to engineer the E. coli strain. First, naturally existing metabolic pathways for the biosynthesis of 1,3-diaminopropane were introduced into a virtual cell in silico to determine the most efficient metabolic pathway for the 1,3-diaminopropane production. The metabolic pathway selected was then introduced into an E. coli strain and successfully produced 1,3-diaminopropane for the first time in the world.
The research team applied metabolic engineering additionally, and the production titer of 1,3-diaminopropane increased about 21 fold. The Fed-batch fermentation of the engineered E. coli strain produced 13 grams per liter of 1,3-diaminoproapne. With this technology, 1,3-diaminopropane can be produced using renewable biomass, and it will be the starting point for replacing the current petroleum-based processes with bio-based processes.
Professor Lee said, “Our study suggested a possibility to produce 1,3-diaminopropane based on biorefinery. Further study will be done to increase the titer and productivity of 1,3-diaminopropane.”
This work was published online in Scientific Reports on August 11, 2015.
Reference: Chae, T.U. et al. "Metabolic engineering of Escherichia coli for the production of 1,3-diaminopropane, a three carbon diamine," Scientific Reports:
http://www.nature.com/articles/srep13040
This research was supported by the Technology Development Program to Solve Climate Changes on Systems Metabolic Engineering for Biorefineries from Ministry of Science, ICT and Future Planning (MSIP) through the National Research Foundation (NRF) of Korea.
Figure 1: Metabolic engineering strategies for 1,3-diaminopropane production using C4 pathway
Figure 2: Fed-batch fermentation profiles of two final engineered E. coli strains
2015.08.12 View 12530 -
International Undergraduate Conference ICISTS-KAIST 2015 and ICISTS-KAIST Public Colloquium Held on August 3, 2015 at KAIST
The ICISTS-KAIST 2015, an international conference organized by a student organization called the International Conference for the Integration of Science, Technology, and Society at KAIST, was held from August 3rd to 7th at the KAIST campus and ICC Hotel in Daejeon. This year’s conference theme was “Shaping the Future.” Over 300 undergraduate students from more than 20 countries joined the event. The conference offered opportunities to explore emerging issues in science and technology, particularly in the fields of robotics, medicine, and science communication.
Vitalic Buterin, a rising scientist who received the 2014 World Technology Award for his development of the Ethereum Project, and Alan Irwin, a renowned scholar in science communication at the Copenhagen Business School in Denmark, were invited as keynote speakers. The list of other speakers included Stefan Lorenz Sorgner, the Director and Co-founder of the Beyond Humanism Network; Wendell Wallach, a scholar at Yale University's Interdisciplinary Center for Bioethics; and Hideto Nakajima, a professor at the Department of History, Philosophy and Social Studies of Science and Technology at Tokyo Institute of Technology.
As part of the ICISTS-KAIST 2015, ICISTS also hosted a public colloquium on August 5, 2015 at the Science Hall in Daejeon National Science Museum. Ko San, the Director of TIDE Institute; Hyo-Joon Woo, the Chief Executive Officer of Fransen; and Dong-Il Jung, the Chief Executive Officer of iDrone participated as the speakers.
2015.07.29 View 9543