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KAIST Hosts a Symposium on IPR
KAIST’s Graduate School of Future Strategy (http://futures.kaist.ac.kr) hosted a symposium entitled “Future Strategies to Grow Korea as the Hub for the World’s Intellectual Property Rights (IPRs)” under the theme of “Patent Laws and a Revised Bill for the Code of Civil Procedures” in the National Assembly’s Memorial Hall on April 9, 2015.
Experts who attended the symposium included Professor James Dator, Director of the Hawaii Research Center for Futures Studies, Sang-Wook Han, a lawyer and Vice President of Korea Intellectual Property Protection Association (KIPRA), and Min Seo, a former Chairman of Civil Law Revision Commission of the Ministry of Justice, Korea.
The event consisted of special lectures, patent law presentations, a revised bill for the code of civil procedures in patent law, and a general discussion forum. Professor Dator, the keynote speaker, addressed the future of intellectual property. San-Wook Han (KIPRA) talked about new and effective changes in Korean patent law such as the compensation against IPR violations and the reduction of legal burden of proof in IPR disputes. Min Seo from the Ministry of Justice moderated a panel of eight members, which offered an in-depth discussion on the revised bill.
A ceremony for “The Third Future Strategy Award” was also held at the symposium. Yeon-Soo Park, former Administrator of the National Emergency Management Agency, received the award for his work on the Northeast Asian International Business Center City Project which enabled the construction of Incheon International Airport and Songdo International City.
2015.04.09 View 9971 -
Professor Rim Presents at IAEA Workshop in Vienna
Professor Chun-Taek Rim of the Department of Nuclear and Quantum Engineering at KAIST recently attended the International Atomic Energy Agency (IAEA)’s workshop on the Application of Wireless Technologies in Nuclear Power Plant Instrumentation and Control System. It took place on March 30-April 2, 2015, in Vienna, Austria.
Representing Korea, Professor Rim gave a talk entitled “Highly Reliable Wireless Power and Communications under Severe Accident of Nuclear Power Plants (NPPs).” About 20 industry experts from 12 countries such as AREVA (France), Westinghouse (US), Oak Ridge National Laboratory (US), Hitachi (Japan), and ENEA (Italy) joined the meeting.
The IAEA hosted the workshop to explore the application of wireless technology for the operation and management of NPPs. It formed a committee consisting of eminent professionals worldwide in NPP instrumentation and control systems, communications, and nuclear power to examine this issue in-depth and to conduct various research projects for the next three years.
In particular, the committee will concentrate its research on improving the reliability and safety of using wireless technology, not only in the normal operation of nuclear plants but also in extreme conditions such as the Fukushima Daiichi nuclear accident. The complementation, economic feasibility, and standardization of NPPs when applying wireless technology will be also discussed.
Professor Rim currently leads the Nuclear Power Electronics
and Robotics Lab at KAIST (http://tesla.kaist.ac.kr/index_eng.php?lag=eng).
Picture 1: Professors Rim presents his topic at the IAEA Workshop in Vienna.
Picture 2: The IAEA Workshop Participants
2015.04.07 View 11309 -
Anti-Cancer Therapy Delivering Drug to an Entire Tumor Developed
KAIST’s Department of Bio and Brain Engineering Professor Ji-Ho Park and his team successfully developed a new highly efficacious anti-cancer nanotechnology by delivering anti-cancer drugs uniformly to an entire tumor. Their research results were published in Nano Letters online on March 31, 2015.
To treat inoperable tumors, anti-cancer medicine is commonly used. However, efficient drug delivery to tumor cells is often difficult, treating an entire tumor with drugs even more so.
Using the existing drug delivery systems, including nanotechnology, a drug can be delivered only to tumor cells near blood vessels, leaving cells at the heart of a tumor intact. Since most drugs are injected into the bloodstream, tumor recurrence post medication is frequent.
Therefore, the team used liposomes that can fuse to the cell membrane and enter the cell. Once inside liposomes the drug can travel into the bloodstream, enter tumor cells near blood vessels, where they are loaded to exosomes, which are naturally occurring nanoparticles in the body. Since exosomes can travel between cells, the drug can be delivered efficiently into inner cells of the tumor.
Exosomes, which are secreted by cells that exist in the tumor microenvironment, is known to have an important role in tumor progression and metastasis since they transfer biological materials between cells. The research team started the investigation recognizing the possibility of delivering the anti-cancer drug to the entire tumor using exosomes.
The team injected the light-sensitive anti-cancer drug using their new delivery technique into experimental mice. The researchers applied light to the tumor site to activate the anti-cancer treatment and analyzed a tissue sample. They observed the effects of the anti-cancer drug in the entire tumor tissue.
The team’s results establish a ground-breaking foothold in drug delivery technology development that can be tailored to specific diseases by understanding its microenvironment. The work paves the way to more effective drug delivery systems for many chronic diseases, including cancer tumors that were difficult to treat due to the inability to penetrate deep into the tissue.
The team is currently conducting experiments with other anti-cancer drugs, which are being developed by pharmaceutical companies, using their tumor-penetrating drug delivery nanotechnology, to identify its effects on malignant tumors.
Professor Park said, “This research is the first to apply biological nanoparticles, exosomes that are continuously secreted and can transfer materials to neighboring cells, to deliver drugs directly to the heart of tumor.”
Picture: Incorporation of hydrophilic and hydrophobic compounds into membrane vesicles by engineering the parental cells via synthetic liposomes.
2015.04.07 View 11089 -
Professor Shim Featured with His Drone System in IEEE Spectrum
The IEEE Spectrum, a technology and science magazine published by the Institute of Electrical and Electronics Engineers (IEEE), featured an article of KAIST’s autonomous unmanned aerial vehicles (UAVs) entitled “South Korea Prepares for Drone vs. Drone Combat,” posted on April 1, 2015.
The article introduces the anti-drone defense system being developed by Professor “David” Hyunchul Shim of the Department of Aerospace Engineering at KAIST. With the goal of developing guard drones that can detect and capture unknown UAVs, the anti-drone defense system consists of reconnaissance drones, agile multi-rotor UAVs equipped with nets which are dropped to snare enemy drones, and transport UAVs to carry smaller drones.
Professor Shim currently leads KAIST’s Unmanned System Research Group (USRG, http://unmanned.kaist.ac.kr/) and Center of Field Robotics for Innovation, Exploration, aNd Defense (C-FRIEND).
For the article, please go to http://spectrum.ieee.org/automaton/robotics/aerial-robots/south-korea-drone-vs-drone.
2015.04.02 View 11457 -
Mutations Occurring Only in Brain Responsible for Intractable Epilepsy Identified
KAIST researchers have discovered that brain somatic mutations in MTOR gene induce intractable epilepsy and suggest a precision medicine to treat epileptic seizures.
Epilepsy is a brain disorder which afflicts more than 50 million people worldwide. Many epilepsy patients can control their symptoms through medication, but about 30% suffer from intractable epilepsy and are unable to manage the disease with drugs. Intractable epilepsy causes multiple seizures, permanent mental, physical, and developmental disabilities, and even death. Therefore, surgical removal of the affected area from the brain has been practiced as a treatment for patients with medically refractory seizures, but this too fails to provide a complete solution because only 60% of the patients who undergo surgery are rendered free of seizures.
A Korean research team led by Professor Jeong Ho Lee of the Graduate School of Medical Science and Engineering at the Korea Advanced Institute of Science and Technology (KAIST) and Professor Dong-Seok Kim of Epilepsy Research Center at Yonsei University College of Medicine has recently identified brain somatic mutations in the gene of mechanistic target of rapamycin (MTOR) as the cause of focal cortical dysplasia type II (FCDII), one of the most important and common inducers to intractable epilepsy, particularly in children. They propose a targeted therapy to lessen epileptic seizures by suppressing the activation of mTOR kinase, a signaling protein in the brain. Their research results were published online in Nature Medicine on March 23, 2015.
FCDII contributes to the abnormal developments of the cerebral cortex, ranging from cortical disruption to severe forms of cortical dyslamination, balloon cells, and dysplastic neurons. The research team studied 77 FCDII patients with intractable epilepsy who had received a surgery to remove the affected regions from the brain. The researchers used various deep sequencing technologies to conduct comparative DNA analysis of the samples obtained from the patients’ brain and blood, or saliva. They reported that about 16% of the studied patients had somatic mutations in their brain. Such mutations, however, did not take place in their blood or saliva DNA.
Professor Jeong Ho Lee of KAIST said, “This is an important finding. Unlike our previous belief that genetic mutations causing intractable epilepsy exist anywhere in the human body including blood, specific gene mutations incurred only in the brain can lead to intractable epilepsy. From our animal models, we could see how a small fraction of mutations carrying neurons in the brain could affect its entire function.”
The research team recapitulated the pathogenesis of intractable epilepsy by inducing the focal cortical expression of mutated mTOR in the mouse brain via electroporation method and observed as the mouse develop epileptic symptoms. They then treated these mice with the drug called “rapamycin” to inhibit the activity of mTOR protein and observed that it suppressed the development of epileptic seizures with cytomegalic neurons.
“Our study offers the first evidence that brain-somatic activating mutations in MTOR cause FCDII and identifies mTOR as a treatment target for intractable epilepsy,” said co-author Dr. Dong-Seok Kim, a neurosurgeon at Yonsei Medical Center with the country’s largest surgical experiences in treating patients with this condition.
The research paper is titled “Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy.” (Digital Object Identifier #: 10.1038/nm.3824)
Picture 1: A schematic image to show how to detect brain specific mutation using next-generation sequencing technology with blood-brain paired sample. Simple comparison of non-overlapping mutations between affected and unaffected tissues is able to detect brain specific mutations.
Picture 2: A schematic image to show how to generate focal cortical dysplasia mouse model. This mouse model open the new window of drug screening for seizure patients.
Picture 3: Targeted medicine can rescue the focal cortical dysplasia symptoms including cytomegalic neuron & intractable epilepsy.
2015.03.25 View 13268 -
KAIST Clinic's Dr. Joo-yeon Kim Receives Minister's Award
Dr. Joo-yeon Kim receives citation on “The Fifth Tuberculosis Prevention Day” for her contribution to campus tuberculosis outbreak prevention.
Dr. Joo-Yeon Kim, the general manager of medical services of KAIST Clinic, received an award from the Korean Ministry of Health and Welfare on March 24, 2015. The award ceremony took place during “The Fifth Tuberculosis Prevention Day,” hosted by the Ministry of Health and Welfare and supervised by the Korea Centers for Disease Control and Prevention. The event was held at Seoul Sejong Cultural Center with 300 distinguished guests in attendance including the Minister of Health and Welfare, the Committee Members of the National Assembly Health and Welfare Committee, and the Director of Korea Centers for Disease Control Prevention.
The award acknowledges Dr. Kim’s contribution to curbing a tuberculosis (TB) outbreak on KAIST’s campus in 2013. In cooperation with the Infectious Disease Prevention Committee in KAIST, Korea Centers for Disease Control and Prevention, and Yuseong Public Health Centre, Dr. Kim’s swift treatment and rigorous control of both TB and latent TB patients prevented further outbreaks.
The KAIST Clinic is the first university-affiliated clinic established in September 2010 after Neil Pappalardo, the President of MEDITEC in the US, donated $2.5 million to KAIST. It is currently running 10 medical departments including those in family medicine, stress clinic, and dentistry to provide medical care to students and staff.
Every March 24 marks the annual “Tuberculosis Prevention Day” and “World Tuberculosis Day.” The “World Tuberculosis Day” was established in 1982 to promote TB prevention and early detection. It commemorated the 100th year anniversary of the discovery of M. tuberculosis on March 24, 1883 by the German bacteriologist Robert Koch.
According to the TB Prevention Act (Article 4), Korea marks “The Tuberculosis Prevention Day” alongside the “World Tuberculosis Day” on March 24 to raise public awareness of the magnitude of the disease and the importance of prevention.
2015.03.25 View 7982 -
KVIP Opened in Pangyo
KAIST has opened the KAIST Venture Innovation Program (KVIP) in its Center for Industry Outreach, designed for executive and high-ranking officers of venture companies. Located in Pangyo Techno Valley, KAIST’s Center for Industry Outreach was established in collaboration with the government of Gyeonggi Province to support venture companies in Pangyo for business management training, venture networking, and university-industry cooperation.
The program will be held every Monday for 12 weeks from April 13 to July 6 in KAIST’s Center for Industry Outreach. This executive education program mainly focuses on solving problems that arise when a medium-sized venture company is in the course of growing into a global corporation. The program is divided into four courses which will cover business management, competition in the global market, transformation of a company, and technological innovation.
Professors from various departments at KAIST will give lectures on their fields. Professor Jaeseung Jeong from the Bio and Brain Engineering Department, Professor Hoi-Jun Yoo from the Electrical Engineering Department, Professor Sangmin Bae from the Industrial Design Department, and Professor Kwangjae Sung from the Business and Technology Management Department will each deliver lectures on brain engineering, semiconductor, design, and restructuring.
Industry experts are also invited to give talks, including Dr. Dae-Gyu Byun, the Chief Executive Officer and President of HUMAX Electronics, Dr. Gwang-Cheol Choi, the Chief Executive Officer of SK Engineering & Construction, Mr. Il-young Kim, the former Chief Executive Officer of KT, Dr. Jae-hoon Jeong, the President of the Korea Institute for the Advancement of Technology (KIAT), Dr. Intak Bae, the Chief Executive Officer of Summit Partners, and Mr. Kyung-taek Kwak, a film director.
The department has started recruiting first round applicants for the program, targeting executive and high-ranking officers of middle-sized venture companies. The details of the program can be found on its website, kvip.kaist.ac.kr.
2015.03.23 View 9460 -
KAIST and Hancom Sign for Development of Mobile Healthcare
KAIST signed a memorandum of understanding with Hancom, Inc., an office suite developer in Korea, to foster mobile healthcare software programs. President Steve Kang and Chairman Sang-Chul Kim of Hancom held a signing ceremony on March 13, 2015 at the KAIST campus.
Based on the agreement, KAIST and Hancom will exchange research personnel to build Dr. M, a smart healthcare platform developed by the university, collaborate in research and development, and cooperate in the transfer of research developments from the university to the software industry including Hancom.
KAIST and Hancom also signed a memorandum of understanding on the development of software in April 2014. The Hancom-KAIST Research Center opened on campus last October.
2015.03.20 View 8468 -
KAIST Exhibits Socially Benign Technologies
Exhibited 29 products that address the need to solve social issues such as a Braille printer
Students from the KAIST Idea Factory, a startup program for undergraduates operated by the Research Institute for Social Technology and Innovation (RISTI), hosted an exhibition presenting their research prototypes. The Idea Factory provides students with opportunities to try out new ideas and develop innovative technologies.
The exhibition was held at the Creative Learning building on campus on March 20, 2015. Students displayed 29 inventions, showcasing technologies to address important social issues. The exhibit included products and technologies developed by the students or already commercialized by small businesses such as a Braille printer, a hydrogen peroxide-oxygen respirator for vessel accidents, and an educational 3D printer. The small business exhibits included a removable additional power unit for wheelchairs, agricultural product anti-theft system, and security lighting.
KAIST also hosted a social technology innovation symposium in KAIST Institute Building on the same day. The theme of the symposium was the “Integration of Technological Innovation and Social Innovation – Social Technology Innovation.”
The key note speaker, Director Heung-Kyu Lee of RISTI, KAIST, presented a lecture on the topic, “The Meaning of Social Technology Innovation: System Change.” His talk was followed by Hyuk-Jin Choi of the Korea Social Enterprise Promotion Agency on “Social Economic Organizations of Korea and Social Technology,” and Jae-Sun Kim of The Grassroots on “Search for Social Innovation and Social Economy.”
The supervisor of the event, Director Lee said, “This exhibit focuses on technologies that could help the underprivileged. We will continue to support students’ ideas and small businesses’ endeavors to develop these technologies.”
KAIST established the Idea Factory in 2014 to assist KAIST students to commercialize creative and innovative ideas. The Idea Factory made a key contribution in commercializing the educational 3D printers last year.
Picture: A Braille Printer
2015.03.20 View 6773 -
Emeritus Professors' Social Service for Embracing Multicultural Families
Korea has become a melting pot over recent years, with many families embracing diverse nationalities, cultures, and ethnicities. A group of KAIST emeritus professors volunteered to help these multicultural families, which are often formed through international marriages, better cope with life in Korea by creating a continuing education program called “Multicultural Mother School.”
The school admitted a total of ten non-Korean mothers for its first class and held an entrance ceremony for the students on March 14, 2015, at the IFC Hope Church in Daejeon. Classes began since March 16, 2015, offering the first lecture to students remotely via the Internet.
Professor Emeritus Byung-Kyu Choi, who organized the volunteering program and is the director of the Multicultural Mother School, said, “About 5% of newborns in Korea currently come from multicultural families. It is important that we should support them to assimilate well into the Korean society. Since 60% of multicultural children have yet to enter the public school system, particularly at the elementary schools level, offering their mothers opportunities to learn more about Korea will serve a greater good.”
2015.03.14 View 5767 -
KAIST Introduces New UI for K-Glass 2
A newly developed user interface, the “i-Mouse,” in the K-Glass 2 tracks the user’s gaze and connects the device to the Internet through blinking eyes such as winks. This low-power interface provides smart glasses with an excellent user experience, with a long-lasting battery and augmented reality.
Smart glasses are wearable computers that will likely lead to the growth of the Internet of Things. Currently available smart glasses, however, reveal a set of problems for commercialization, such as short battery life and low energy efficiency. In addition, glasses that use voice commands have raised the issue of privacy concerns.
A research team led by Professor Hoi-Jun Yoo of the Electrical Engineering Department at the Korea Advanced Institute of Science and Technology (KAIST) has recently developed an upgraded model of the K-Glass (http://www.eurekalert.org/pub_releases/2014-02/tkai-kdl021714.php) called “K-Glass 2.”
K-Glass 2 detects users’ eye movements to point the cursor to recognize computer icons or objects in the Internet, and uses winks for commands. The researchers call this interface the “i-Mouse,” which removes the need to use hands or voice to control a mouse or touchpad. Like its predecessor, K-Glass 2 also employs augmented reality, displaying in real time the relevant, complementary information in the form of text, 3D graphics, images, and audio over the target objects selected by users.
The research results were presented, and K-Glass 2’s successful operation was demonstrated on-site to the 2015 Institute of Electrical and Electronics Engineers (IEEE) International Solid-State Circuits Conference (ISSCC) held on February 23-25, 2015 in San Francisco. The title of the paper was “A 2.71nJ/Pixel 3D-Stacked Gaze-Activated Object Recognition System for Low-power Mobile HMD Applications” (http://ieeexplore.ieee.org/Xplore/home.jsp).
The i-Mouse is a new user interface for smart glasses in which the gaze-image sensor (GIS) and object recognition processor (ORP) are stacked vertically to form a small chip. When three infrared LEDs (light-emitting diodes) built into the K-Glass 2 are projected into the user’s eyes, GIS recognizes their focal point and estimates the possible locations of the gaze as the user glances over the display screen. Then the electro-oculography sensor embedded on the nose pads reads the user’s eyelid movements, for example, winks, to click the selection. It is worth noting that the ORP is wired to perform only within the selected region of interest (ROI) by users. This results in a significant saving of battery life. Compared to the previous ORP chips, this chip uses 3.4 times less power, consuming on average 75 milliwatts (mW), thereby helping K-Glass 2 to run for almost 24 hours on a single charge.
Professor Yoo said, “The smart glass industry will surely grow as we see the Internet of Things becomes commonplace in the future. In order to expedite the commercial use of smart glasses, improving the user interface (UI) and the user experience (UX) are just as important as the development of compact-size, low-power wearable platforms with high energy efficiency. We have demonstrated such advancement through our K-Glass 2. Using the i-Mouse, K-Glass 2 can provide complicated augmented reality with low power through eye clicking.”
Professor Yoo and his doctoral student, Injoon Hong, conducted this research under the sponsorship of the Brain-mimicking Artificial Intelligence Many-core Processor project by the Ministry of Science, ICT and Future Planning in the Republic of Korea.
Youtube Link:
https://www.youtube.com/watchv=JaYtYK9E7p0&list=PLXmuftxI6pTW2jdIf69teY7QDXdI3Ougr
Picture 1: K-Glass 2
K-Glass 2 can detect eye movements and click computer icons via users’ winking.
Picture 2: Object Recognition Processor Chip
This picture shows a gaze-activated object-recognition system.
Picture 3: Augmented Reality Integrated into K-Glass 2
Users receive additional visual information overlaid on the objects they select.
2015.03.13 View 15473 -
Professor Sangyong Jon Appointed Fellow of AIMBE
Professor Sangyong Jon of the Department of Biological Sciences at KAIST has been appointed a member of the American Institute for Medical and Biological Engineering (AIMBE) fellowship.
Established in 1991, AIMBE is a non-profit organization based in Washington, D.C., representing 50,000 individuals and the top 2% of medical and biological engineers. AIMBE provides policy advice and advocacy for medical and biological engineering for the benefit of humanity. It has had about 1,500 fellows over the past 25 years. Among the members, only 110 are non-American nationalities.
Following the appointment of Dr. Hae-Bang Lee, the former senior researcher at the Korean Research Institute of Chemical Technology, and Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering at KAIST, Professor Jon is the third Korean to become an AIMBE fellow. He had an induction ceremony for the appointment of his fellowship at the AIMBE’s Annual Event held on March 15-17, 2015 in Washington, D.C.
An authority on nanomedicine, Professor Jon has developed many original technologies including multi-functional Theranostics nano particles for the diagnosis and treatment of diseases. He received the Most Cited Paper Award from Theranostics, an academic journal specialized in nanomedicine, last February.
Additionally, Professor Jon is a leading researcher in the field of translational medicine, using a multi-disciplinary, highly collaborative, “Bench to Bedside” approach for disease treatment and prevention. He created a biotechnology venture company and transferred research developments to the industry in Korea.
2015.03.12 View 11413