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KAIST to Participate in Summer Davos Forum 2016 in China
A group of KAIST researchers will share their insights on the future and challenges of the current technological innovations impacting all aspects of society, while showcasing their research excellence in artificial intelligence and robotics.
Scientific and technological breakthroughs are more important than ever as key agents to drive social, economic, and political changes and advancements in today’s world. The World Economic Forum (WEF), an international organization that provides one of the broadest engagement platforms to address issues of major concern to the global community, will discuss the effects of these breakthroughs at its 10th Annual Meeting of the New Champions, a.k.a., the Summer Davos Forum, in Tianjin, China, June 26-28, 2016.
Three professors from the Korea Advanced Institute of Science and Technology (KAIST) will join the Annual Meeting and offer their expertise in the fields of biotechnology, artificial intelligence, and robotics to explore the conference theme, “The Fourth Industrial Revolution and Its Transformational Impact.” The Fourth Industrial Revolution, a term coined by WEF founder, Klaus Schwab, is characterized by a range of new technologies that fuse the physical, digital, and biological worlds, such as the Internet of Things, cloud computing, and automation.
Distinguished Professor Sang Yup Lee of the Chemical and Biomolecular Engineering Department will speak at the Experts Reception to be held on June 25, 2016 on the topic of “The Summer Davos Forum and Science and Technology in Asia.” On June 27, 2016, he will participate in two separate discussion sessions.
In the first session entitled “What If Drugs Are Printed from the Internet?,” Professor Lee will discuss the impacts of advancements in biotechnology and 3D printing technology on the future of medicine with Nita A. Farahany, a Duke University professor. Clare Matterson, the Director of Strategy at Wellcome Trust in the United Kingdom, will serve as the moderator. The discussants will note recent developments made in the way patients receive their medicine, for example, downloading drugs directly from the internet and the production of yeast strains to make opioids for pain treatment through systems metabolic engineering. They will also suggest how these emerging technologies will transform the landscape of the pharmaceutical industry in the years to come.
In the second session, “Lessons for Life,” Professor Lee will talk about how to nurture life-long learning and creativity to support personal and professional growth necessary in an era of the new industrial revolution.
During the Annual Meeting, Professors Jong-Hwan Kim of the Electrical Engineering School and David Hyunchul Shim of the Aerospace Department will host, together with researchers from Carnegie Mellon University and AnthroTronix, an engineering research and development company, a technological exhibition on robotics. Professor Kim, the founder of the internally renowned Robot World Cup, will showcase his humanoid soccer-playing micro-robots and display their various cutting-edge technologies such as imaging processing, artificial intelligence, walking, and balancing. Professor Shim will present a human-like robotic piloting system, PIBOT, which autonomously operates a simulated flight program by employing control sticks and guiding an airplane from takeoff to landing.
In addition, the two professors will join Professor Lee, who is also a moderator, to host a KAIST-led session on June 26, 2016, entitled “Science in Depth: From Deep Learning to Autonomous Machines.” Professors Kim and Shim will explore new opportunities and challenges in their fields from machine learning to autonomous robotics, including unmanned vehicles and drones.
Since 2011, KAIST has participated in the World Economic Forum’s two flagship conferences, the January and June Davos Forums, to introduce outstanding talents, share their latest research achievements, and interact with global leaders.
KAIST President Steve Kang said, “It is important for KAIST to be involved in global forums that identify issues critical to humanity and seek answers to solve them, and where our skills and knowledge in science and technology can play a meaningful role. The Annual Meeting in China will become another venue to accomplish this.”
2016.06.27 View 13557 -
Unveiling the Distinctive Features of Industrial Microorganism
KAIST researchers have sequenced the whole genome of Clostridium tyrobutyricum, which has a higher tolerance to toxic chemicals, such as 1-butanol, compared to other clostridial bacterial strains.
Clostridium tyrobutyricum, a Gram-positive, anaerobic spore-forming bacterium, is considered a promising industrial host strain for the production of various chemicals including butyric acid which has many applications in different industries such as a precursor to biofuels. Despite such potential, C. tyrobutyricum has received little attention, mainly due to a limited understanding of its genotypic and metabolic characteristics at the genome level.
A Korean research team headed by Distinguished Professor Sang Yup Lee of the Chemical and Biomolecular Engineering Department at the Korea Advanced Institute of Science and Technology (KAIST) deciphered the genome sequence of C. tyrobutyricum and its proteome profiles during the course of batch fermentation. As a result, the research team learned that the bacterium is not only capable of producing a large amount of butyric acid but also can tolerate toxic compounds such as 1-butanol. The research results were published in mBio on June 14, 2016.
The team adopted a genoproteomic approach, combining genomics and proteomics, to investigate the metabolic features of C. tyrobutyricum. Unlike Clostridium acetobutylicum, the most widely used organism for 1-butanol production, C. tyrobutyricum has a novel butyrate-producing pathway and various mechanisms for energy conservation under anaerobic conditions. The expression of various metabolic genes, including those involved in butyrate formation, was analyzed using the “shotgun” proteome approach.
To date, the bio-based production of 1-butanol, a next-generation biofuel, has relied on several clostridial hosts including C. acetobutylicum and C. beijerinckii. However, these organisms have a low tolerance against 1-butanol even though they are naturally capable of producing it. C. tyrobutyricum cannot produce 1-butanol itself, but has a higher 1-butanol-tolerance and rapid uptake of monosaccharides, compared to those two species.
The team identified most of the genes involved in the central metabolism of C. tyrobutyricum from the whole-genome and shotgun proteome data, and this study will accelerate the bacterium’s engineering to produce useful chemicals including butyric acid and 1-butanol, replacing traditional bacterial hosts.
Professor Lee said,
“The unique metabolic features and energy conservation mechanisms of C. tyrobutyricum can be employed in the various microbial hosts we have previously developed to further improve their productivity and yield. Moreover, findings on C. tyrobutyricum revealed by this study will be the first step to directly engineer this bacterium.”
Director Jin-Woo Kim at the Platform Technology Division of the Ministry of Science, ICT and Future Planning of Korea, who oversees the Technology Development Program to Solve Climate Change, said,
“Over the years, Professor Lee’s team has researched the development of a bio-refinery system to produce natural and non-natural chemicals with the systems metabolic engineering of microorganisms. They were able to design strategies for the development of diverse industrial microbial strains to produce useful chemicals from inedible biomass-based carbon dioxide fixation. We believe the efficient production of butyric acid using a metabolic engineering approach will play an important role in the establishment of a bioprocess for chemical production.”
The title of the research paper is “Deciphering Clostridium tyrobutyricum Metabolism Based on the Who-Genome Sequence and Proteome Analyses.” (DOI: 10.1128/mBio.00743-16)
The lead authors are Joungmin Lee, a post-doctoral fellow in the BioProcess Research Center at KAIST, currently working in CJ CheilJedang Research Institute; Yu-Sin Jang, a research fellow in the BioProcess Research Center at KAIST, currently working at Gyeongsang National University as an assistant professor; and Mee-Jung Han, an assistant professor in the Environmental Engineering and Energy Department at Dongyang University. Jin Young Kim, a senior researcher at the Korea Basic Science Institute, also participated in the research.
This research was supported by the Technology Development Program to Solve Climate Change’s research project entitled “Systems Metabolic Engineering for Biorefineries” from the Ministry of Science, ICT and Future Planning through the National Research Foundation of Korea (NRF-2012M1A2A2026556).
Schematic Diagram of C. tyrobutyricum’s Genome Sequence and Its Proteome Profiles
The picture below shows the complete genome sequence, global protein expression profiles, and the genome-based metabolic characteristics during batch fermentation of C. tyrobutyricum.
2016.06.20 View 11396 -
KAIST and McKinsey Korea Agreed to Cultivate Management Leaders
KAIST and McKinsey Korea signed a memorandum of understanding (MOU) for the “Joint Research on Innovative Instructional Method to Cultivate Future Management Leaders” on April 8, 2016, at the SUPEX Management Hall of KAIST Management School in Seoul.
Under the MOU, both organizations will cooperate in the following research areas: management strategies to overcome the low growth of Korean economy, instructional methods to foster leaders in the field of business and management, and innovative management systems for business.
President Kang said, “We are pleased to work with McKinsey, a worldwide management consulting firm, to foster leaders in science and business. As we see more demanding challenges of managing and leading science-based businesses today, this alliance is indeed timely and will be very helpful.”
2016.04.15 View 6284 -
KAIST Hosts the 2016 IPFGRU
More than 120 senior representatives from 65 universities around the world will convene this month in Seoul to discuss the social responsibilities of higher education and strategic global partnerships among academia, research, and industry to advance socio-economic values.
Higher education as a driver of change to address the social and global challenges facing humanity in the 21st century has never been as important as it is today.
KAIST will raise the topic of higher education as a driver of social change, innovation, and entrepreneurship with the heads of global universities at its seventh international forum to be held on April 11-12, 2016 at the Grand Hyatt Hotel in Seoul, the Republic of Korea.
The 2016 International Presidential Forum on Global Research Universities (IPFGRU) will bring over 120 presidents and vice presidents of 65 research universities and institutes from 36 nations together to discuss the theme of “Social Responsibilities of Higher Education and Strategic Global Partnership.”
Presidents Sung-Mo Kang of KAIST, Jacques Biot of École Polytechnique in France, and Peretz Lavie of the Technion-Israel Institute of Technology will address the conference as plenary speakers.
President Kang will speak about KAIST’s initiatives to produce creative talents through student-centered education, entrepreneurship curricula, and the integration of humanities into cutting-edge research programs. His presentation, titled “The Fostering of Creative Talents and the Social Responsibility of Research Universities in the New Era,” introduces KAIST’s educational philosophy which can be represented as π. A broad range of understanding in basic disciplines (the horizontal line) is supported with one prong of in-depth knowledge in a chosen field and the other in entrepreneurial spirit.
KAIST graduates have demonstrated extraordinary leadership in research, academia, business, and public service. Nearly 25% of the research and development personnel at Samsung Electronics are KAIST Ph.D. holders. President Kang also describes KAIST’s latest endeavor to turn a university-led entrepreneurial activity into a stable business based on research outcomes and campus innovations. The K-School, a one-year master’s degree program on entrepreneurship and innovation, has just launched and is expecting to receive its first batch of students this fall. The K-School is envisioned to continue the university’s legacy as a major feeder for startups in Korea.
President Lavie will give a talk on “Fostering an Innovation and Entrepreneurship (I&E) Ecosystem in Israel,” in which he describes how the Technion-Israel Institute has become integral to the foundation of the nation’s I&E platform. Since its establishment in 1912, the university has become a key player in the growth of Israel’s industry, science, and technology while nurturing the majority of the nation’s top-notch researchers, innovators, and entrepreneurs. Technion graduates have created more than 2,000 companies in Israel alone, generating 100,000 jobs and USD 30 billion through mergers and acquisitions.
President Biot will offer his insights into how the future of global research universities will be widely impacted by the emergence of disruptions triggered by the Fourth Industrial Revolution. In his speech entitled “How to Prepare Our Universities for the New Era of Industry 4.0,” he emphasizes that universities should take multi-disciplinary approaches to tackle societal challenges given the complexity of today’s problems ranging from climate change to energy crises, pandemic diseases, and poverty. He argues that universities should identify the needs of students in “Generation Z” who, from birth, have been heavily exposed to the Internet and digital technologies and, thus, universities should develop new educational systems (i.e., University 4.0.) to better prepare these students to cope with Industry 4.0.
The IPFGRU consists of presentations and discussions addressing the following sub-topics:
- Seeking a New Model of Research Universities in a New Era: This session will explore the role of research universities as both innovation drivers and growth engines in an age of robotics, globalization, and digitally-driven markets. In addition, speakers will discuss how to prepare universities for the Industry 4.0 era, and how multidisciplinary approaches and open innovations will play a large part in facilitating translational research and technology transfer.
- Shared Challenges and Responsibilities from a Global Perspective: Universities will share their strategies, policies, and practices to respond to critical issues facing local and global communities such as youth unemployment, the environment, energy, inequality, and entrepreneurship.
- Strategic Global Partnerships for Sustainable Development: Panelists will discuss how to build productive and sustainable partnerships that can generate synergies between education and research.
- Insights into Higher Education: Trends and Development: Participants will examine how universities can stay relevant in an increasingly competitive higher education sector and can assist students to better adapt to opportunities and challenges posed by the new industry of digital transformation and exponentially-growing technologies.
Sung-Hyon Myaeng, the Associate Vice President of the International Office at KAIST and a Co-chair of the 2016 IPFGRU said,
“The IPFGRU was established in 2008 to promote excellence and innovation in higher education with presidents of leading research universities and key policy-makers in the private and public sectors from across the world. Since then, it has served as one of the largest university gatherings in Asia, allowing participants to cooperate and share their expertise, ideas, and best practices taking place in academia, industry, and government.”
“This year’s meeting has recorded the largest number of universities participating, including 28 European schools, 20 Asian institutions, and 8 schools from the Americas, which I believe reflects a sense of urgency that global universities share. One way or another, we must adapt to the rapidly transforming educational and research environment encompassing higher learning,” added Myaeng.
For more information, go to http://forum.kaist.ac.kr.
2016.04.08 View 9993 -
Next-Generation Holographic Microscope for 3D Live Cell Imaging
KAIST researchers have developed a revolutionary bio-medical imaging tool, the HT-1, to view and analyze cells, which is commercially available.
Professor YongKeun Park of the Physics Department at KAIST and his research team have developed a powerful method for 3D imaging of live cells without staining. The researchers announced the launch of their new microscopic tool, the holotomography (HT)-1, to the global marketplace through a Korean start-up that Professor Park co-founded, TomoCube (www.tomocube.com).
Professor Park is a leading researcher in the field of biophotonics and has dedicated much of his research career to working on digital holographic microscopy technology. He collaborated with TomoCube’s R&D team to develop a state-of-the-art, 2D/3D/4D holographic microscope that would allow a real-time label-free visualization of biological cells and tissues.
The HT is an optical analogy of X-ray computed tomography (CT). Both X-ray CT and HT share the same physical principle—the inverse of wave scattering. The difference is that HT uses laser illumination whereas X-ray CT uses X-ray beams. From the measurement of multiple 2D holograms of a cell, coupled with various angles of laser illuminations, the 3D refractive index (RI) distribution of the cell can be reconstructed. The reconstructed 3D RI map provides structural and chemical information of the cell including mass, morphology, protein concentration, and dynamics of the cellular membrane.
The HT enables users to quantitatively and non-invasively investigate the intrinsic properties of biological cells, for example, dry mass and protein concentration. Some of the research team’s breakthroughs that have leveraged HT’s unique and special capabilities can be found in several recent publications, including a lead article on the simultaneous 3D visualization and position tracking of optically trapped particles which was published in Optica on April 20, 2015.
Current fluorescence confocal microscopy techniques require the use of exogenous labeling agents to render high-contrast molecular information. Therefore, drawbacks include possible photo-bleaching, photo-toxicity, and interference with normal molecular activities. Immune or stem cells that need to be reinjected into the body are considered particularly difficult to employ with fluorescence microscopy.
“As one of the two currently available, high-resolution tomographic microscopes in the world, I believe that the HT-1 is the best in class regarding specifications and functionality. Users can see 3D/4D live images of cells, without fixing, coating or staining cells. Sample preparation times are reduced from a few days or hours to just a few minutes,” said Professor Park.
Two Korean hospitals, Seoul National University Hospital in Bundang and Boramae Hospital in Seoul, are using this microscope currently. The research team has also introduced the HT-1 at the Photonics West Exhibition 2016 that took place on February 16-18 in San Francisco, USA.
Professor Park added, “Our technology has set a new paradigm for cell observation under a microscope. I expect that this tomographic microscopy will be more widely used in future in various areas of pharmaceuticals, neuroscience, immunology, hematology, and cell biology.”
Figure 1: HT-1 and Its Specifications
Figure 2: 3D Images of Representative Biological Cells Taken with the HT-1
2016.03.29 View 13671 -
Efficient Methane C-H Bond Activated by KAIST and UPenn Teams
Professor Mu-Hyun Baik of the Chemistry Department at KAIST and his team collaborated with an international team to discover a novel chemical reaction, carbon-hydrogen borylation using methane, and their research results were published in the March 25th issue of Science.
For details, please refer to the following press release from the Institute for Basic Sciences (IBS) in Korea and the University of Pennsylvania in the United States.
Efficient Methane C-H Bond Activation Achieved for the First Time
The Institute for Basic Science, March 24, 2016
Penn Chemists Lay Groundwork for Countless New, Cleaner Uses of Methane
University of Pennsylvania, March 24, 2016
2016.03.25 View 10332 -
KAIST Team Develops Technology to Enable Unzipping of the Graphene Plane
Professor Sang-Wook Kim’s research team of the Material Science and Engineering Department has developed a technique, which enables unzipping of the graphene plane without uncontrollable damage. The research findings were published online on the January 22 issue of Nature Communications.
Graphene is a form of carbon in which its atoms form a honey-comb structure through chemical bonding. If this structure can be cut to a desired form, other carbon materials with nanostructure can be created. Many researchers have tried to obtain the accurate unzipping of graphene structures, but faced challenges doing so.
To break a very strong bond between carbon atoms, an equivalently strong chemical reaction must be induced. But the chemical reaction not only cuts out the desirable borders, but also damages the surrounding ones. Conventional techniques, which cut out graphene at once, damaged the chemical properties of the graphene structure after unzipping. This is similar to wearing out paper while manipulating it.
To solve this problem, the research team adopted “heteroatom doping.” The idea is similar to a sheet of paper being split following a groove drawn on the sheet. After making some regions of the structure unstable by doping other atoms such as nitrogen on a carbon plane, the regions are electrochemically stimulated to split the parts. Nitrogen or other atoms act as the groove on the grapheme plane.
The researchers finely controlled the amount of unzipping graphene by adjusting the amount of heteroatom dopants, from which they were able to create a quality nano graphene without any damage in its 2-dimensional crystalline structure. Using this technique, the researchers were able to obtain a capacitor with state-of-the-art energy transfer speed. The nano graphene can be combined with polymer, metal, and semiconductor nano molecules to form carbon composites.
Professor Kim said, “In order to commercialize this technique, heteroatom doping should be researched further. We plan to develop fabric-like carbon materials with excellent mechanical and electrical properties using this technique.”
Picture 1: Unzipped Carbon Nano Tube
Picture 2: Development of Nano Graphene from Carbon Nano Tube Using Heteroatom Dopants
Korean descriptions translated into English:
Unzipping Process of Graphene
Carbon Nano Tube → Nano Graphen
Heteroatom
This process is similar to a paper being split in two from a tiny hole punched therein.
2016.03.22 View 9515 -
Non-Natural Biomedical Polymers Produced from Microorganisms
KAIST researchers have developed metabolically engineered Escherichia coli strains to synthesize non-natural, biomedically important polymers including poly(lactate-co-glycolate) (PLGA), previously considered impossible to obtain from biobased materials.
Renewable non-food biomass could potentially replace petrochemical raw materials to produce energy sources, useful chemicals, or a vast array of petroleum-based end products such as plastics, lubricants, paints, fertilizers, and vitamin capsules. In recent years, biorefineries which transform non-edible biomass into fuel, heat, power, chemicals, and materials have received a great deal of attention as a sustainable alternative to decreasing the reliance on fossil fuels.
A research team headed by Distinguished Professor Sang Yup Lee of the Chemical and Biomolecular Engineering Department at KAIST has established a biorefinery system to create non-natural polymers from natural sources, allowing various plastics to be made in an environmentally-friendly and sustainable manner. The research results were published online in Nature Biotechnology on March 7, 2016. The print version will be issued in April 2016.
The research team adopted a systems metabolic engineering approach to develop a microorganism that can produce diverse non-natural, biomedically important polymers and succeeded in synthesizing poly(lactate-co-glycolate) (PLGA), a copolymer of two different polymer monomers, lactic and glycolic acid. PLGA is biodegradable, biocompatible, and non-toxic, and has been widely used in biomedical and therapeutic applications such as surgical sutures, prosthetic devices, drug delivery, and tissue engineering.
Inspired by the biosynthesis process for polyhydroxyalkanoates (PHAs), biologically-derived polyesters produced in nature by the bacterial fermentation of sugar or lipids, the research team designed a metabolic pathway for the biosynthesis of PLGA through microbial fermentation directly from carbohydrates in Escherichia coli (E. coli) strains.
The team had previously reported a recombinant E. coli producing PLGA by using the glyoxylate shunt pathway for the generation of glycolate from glucose, which was disclosed in their patents KR10-1575585-0000 (filing date of March 11, 2011), US08883463 and JP5820363. However, they discovered that the polymer content and glycolate fraction of PLGA could not be significantly enhanced via further engineering techniques. Thus, in this research, the team introduced a heterologous pathway to produce glycolate from xylose and succeeded in developing the recombinant E. coli producing PLGA and various novel copolymers much more efficiently.
In order to produce PLGA by microbial fermentation directly from carbohydrates, the team incorporated external and engineered enzymes as catalysts to co-polymerize PLGA while establishing a few additional metabolic pathways for the biosynthesis to produce a range of different non-natural polymers, some for the first time. This bio-based synthetic process for PLGA and other polymers could substitute for the existing complicated chemical production that involves the preparation and purification of precursors, chemical polymerization processes, and the elimination of metal catalysts.
Professor Lee and his team performed in silico genome-scale metabolic simulations of the E. coli cell to predict and analyze changes in the metabolic fluxes of cells which were caused by the introduction of external metabolic pathways. Based on these results, genes are manipulated to optimize metabolic fluxes by eliminating the genes responsible for byproducts formation and enhancing the expression levels of certain genes, thereby achieving the effective production of target polymers as well as stimulating cell growth.
The team utilized the structural basis of broad substrate specificity of the key synthesizing enzyme, PHA synthase, to incorporate various co-monomers with main and side chains of different lengths. These monomers were produced inside the cell by metabolic engineering, and then copolymerized to improve the material properties of PLGA. As a result, a variety of PLGA copolymers with different monomer compositions such as the US Food and Drug Administration (FDA)-approved monomers, 3-hydroxyburate, 4-hydroxyburate, and 6-hydroxyhexanoate, were produced. Newly applied bioplastics such as 5-hydroxyvalerate and 2-hydroxyisovalerate were also made.
The team employed a systems metabolic engineering application which, according to the researchers, is the first successful example of biological production of PGLA and several novel copolymers from renewable biomass by one-step direct fermentation of metabolically engineered E.coli.
Professor Lee said, “We presented important findings that non-natural polymers, such as PLGA which is commonly used for drug delivery or biomedical devices, were produced by a metabolically engineered gut bacterium. Our research is meaningful in that it proposes a platform strategy in metabolic engineering, which can be further utilized in the development of numerous non-natural, useful polymers.”
Director Ilsub Baek at the Platform Technology Division of the Ministry of Science, ICT and Future Planning of Korea, who oversees the Technology Development Program to Solve Climate Change, said, “Professor Lee has led one of our research projects, the Systems Metabolic Engineering for Biorefineries, which began as part of the Ministry’s Technology Development Program to Solve Climate Change. He and his team have continuously achieved promising results and been attracting greater interest from the global scientific community. As climate change technology grows more important, this research on the biological production of non-natural, high value polymers will have a great impact on science and industry.”
The title of the research paper is “One-step Fermentative Production of Poly(lactate-co-glycolate) from Carbohydrates in Escherichia coli (DOI: 10.1038/nbt.3485).” The lead authors are So Young Choi, a Ph.D. candidate in the Department of Chemical and Biomolecular Engineering at KAIST, and Si Jae Park, Assistant Professor of the Environmental Engineering and Energy Department at Myongji University. Won Jun Kim and Jung Eun Yang, both doctoral students in the Department of Chemical and Biomolecular Engineering at KAIST, also participated in the research.
This research was supported by the Technology Development Program to Solve Climate Change’s research project titled “Systems Metabolic Engineering for Biorefineries” from the Ministry of Science, ICT and Future Planning through the National Research Foundation of Korea (NRF-2012M1A2A2026556).
Figure: Production of PLGA and Other Non-Natural Copolymers
This schematic diagram shows the overall conceptualization of how metabolically engineered E. coli produced a variety of PLGAs with different monomer compositions, proposing the chemosynthetic process of non-natural polymers from biomass. The non-natural polymer PLGA and its other copolymers, which were produced by engineered bacteria developed by taking a systems metabolic engineering approach, accumulate in granule forms within a cell.
2016.03.08 View 12614 -
K-Glass 3 Offers Users a Keyboard to Type Text
KAIST researchers upgraded their smart glasses with a low-power multicore processor to employ stereo vision and deep-learning algorithms, making the user interface and experience more intuitive and convenient.
K-Glass, smart glasses reinforced with augmented reality (AR) that were first developed by KAIST in 2014, with the second version released in 2015, is back with an even stronger model. The latest version, which KAIST researchers are calling K-Glass 3, allows users to text a message or type in key words for Internet surfing by offering a virtual keyboard for text and even one for a piano.
Currently, most wearable head-mounted displays (HMDs) suffer from a lack of rich user interfaces, short battery lives, and heavy weight. Some HMDs, such as Google Glass, use a touch panel and voice commands as an interface, but they are considered merely an extension of smartphones and are not optimized for wearable smart glasses. Recently, gaze recognition was proposed for HMDs including K-Glass 2, but gaze cannot be realized as a natural user interface (UI) and experience (UX) due to its limited interactivity and lengthy gaze-calibration time, which can be up to several minutes.
As a solution, Professor Hoi-Jun Yoo and his team from the Electrical Engineering Department recently developed K-Glass 3 with a low-power natural UI and UX processor. This processor is composed of a pre-processing core to implement stereo vision, seven deep-learning cores to accelerate real-time scene recognition within 33 milliseconds, and one rendering engine for the display.
The stereo-vision camera, located on the front of K-Glass 3, works in a manner similar to three dimension (3D) sensing in human vision. The camera’s two lenses, displayed horizontally from one another just like depth perception produced by left and right eyes, take pictures of the same objects or scenes and combine these two different images to extract spatial depth information, which is necessary to reconstruct 3D environments. The camera’s vision algorithm has an energy efficiency of 20 milliwatts on average, allowing it to operate in the Glass more than 24 hours without interruption.
The research team adopted deep-learning-multi core technology dedicated for mobile devices. This technology has greatly improved the Glass’s recognition accuracy with images and speech, while shortening the time needed to process and analyze data. In addition, the Glass’s multi-core processor is advanced enough to become idle when it detects no motion from users. Instead, it executes complex deep-learning algorithms with a minimal power to achieve high performance.
Professor Yoo said, “We have succeeded in fabricating a low-power multi-core processer that consumes only 126 milliwatts of power with a high efficiency rate. It is essential to develop a smaller, lighter, and low-power processor if we want to incorporate the widespread use of smart glasses and wearable devices into everyday life. K-Glass 3’s more intuitive UI and convenient UX permit users to enjoy enhanced AR experiences such as a keyboard or a better, more responsive mouse.”
Along with the research team, UX Factory, a Korean UI and UX developer, participated in the K-Glass 3 project.
These research results entitled “A 126.1mW Real-Time Natural UI/UX Processor with Embedded Deep-Learning Core for Low-Power Smart Glasses” (lead author: Seong-Wook Park, a doctoral student in the Electrical Engineering Department, KAIST) were presented at the 2016 IEEE (Institute of Electrical and Electronics Engineers) International Solid-State Circuits Conference (ISSCC) that took place January 31-February 4, 2016 in San Francisco, California.
YouTube Link: https://youtu.be/If_anx5NerQ
Figure 1: K-Glass 3
K-Glass 3 is equipped with a stereo camera, dual microphones, a WiFi module, and eight batteries to offer higher recognition accuracy and enhanced augmented reality experiences than previous models.
Figure 2: Architecture of the Low-Power Multi-Core Processor
K-Glass 3’s processor is designed to include several cores for pre-processing, deep-learning, and graphic rendering.
Figure 3: Virtual Text and Piano Keyboard
K-Glass 3 can detect hands and recognize their movements to provide users with such augmented reality applications as a virtual text or piano keyboard.
2016.02.26 View 13991 -
KAIST Graduate Han Receives a 2016 PECASE Award
President Barack Obama of the United States (US) announced 105 recipients of the 2016 Presidential Early Career Awards for Scientists and Engineers (PECASE) on February 18. Among the awardees was a graduate from the Department of Electrical Engineering at KAIST.
Dr. Jin-Woo Han has worked as a research scientist at the National Aeronautics and Space Administration (NASA) Ames Research Center since graduating from KAIST in 2010. This year, he is the only awardee who received a doctoral degree from a Korean university to become a recipient of the highest honor bestowed by the US government on science and engineering professionals in the early stages of their independent research careers.
The awards ceremony will take place in early spring at the White House in Washington, D.C.
Dr. Han has been involved in the development of radiation tolerant semiconductor devices as well as radiation and gas sensors under Dr. Meyya Meyyappan, Chief Scientist of the Center for Nanotechnology at NASA Ames Research Center.
KAIST and the NASA Ames Research Center made a research collaboration agreement in 2008, under which KAIST has sent 12 post-doctoral fellows to the center to date.
The PECASE awards, established in 1996 by President Bill Clinton, are coordinated by the Office of Science and Technology Policy within the Executive Office of the US President. Awardees are selected for their pursuit of innovative research at the frontiers of science and technology and their commitment to community services as demonstrated through scientific leadership, public education, or community outreach.
2016.02.23 View 10529 -
Meditox Donates 600 Million KRW Scholarship
On February 17, a Korean biopharmaceutical company Meditox, headed by Chief Executive Officer (CEO) Hyun-Ho Jeong, signed a memorandum of understanding (MOU) with KAIST to establish the “Meditox Fellowship” and donated a total of 600 million Korean won (KRW) to the university to assist in promoting more scientists in the field of biology.
Meditox CEO Hyun-Ho Jeong, KAIST President Steve Kang, Dean of Life Science and Bioengineering College Jung-Hoe Kim, and Dean of the Department of Biological Sciences Byung-Ha Oh participated in the agreement ceremony.
According to the MOU, Meditox will donate 60,000,000 KRW over a ten year period, from which KAIST can draw on to grant scholarships for master’s and doctoral students.
The “Meditox Fellowship” will support promising and enthusiastic students whose finances limit their studies. The first scholarship students for 2016 were: Kwang-Uk Min, In-suk Yeo, Sung-ryung- Lee, Si-on Lee, and Jung-hyun Kim.
Meditox CEO Jeong, who graduated from KAIST’s Department of Biological Sciences, said, "I felt it was important to start the Meditox Fellowship at my alma mater to contribute to the cultivation of outstanding scientists in the field of biological sciences."
He also said that he would plan to launch projects that aim to support not only those who receive the scholarship but also the development of Korea’s biological sciences in general.
President Steve Kang (right) and Chief Executive Officer Hyun-Ho Jeong (left) of Meditox hold the signed memorandum of understanding together.
2016.02.18 View 11282 -
Symposium on Creative Education
KAIST and the Korea Society for Creativity and Application (KSCA) co-hosted a symposium on creative education on January 21, 2016 at the KAIST Business and Management College in Seoul. Along with the symposium, the two organizations also held the Korea "Theory of Inventive Problem Solving" (TRIZ) Festival 2016.
Around 200 experts from academia, industry, and research including Dong-Suk Kim, Dean of the KAIST College of Business and Management and Gui-Chan Park, Director of POSCO Group Academy, attended the symposium.
The event was organized to celebrate the foundation of KSCA and to increase social awareness of creative education and design-related thinking with a "TRIZ approach."
"TRIZ" stands for the “Theory of Inventive Problem Solving” in Russian. It is a problem-solving method based on logic and data, not intuition, which accelerates the project team’s ability to work out issues creatively. The "TRIZ approach" has been widely used among Korean companies including Samsung, LG, and POSCO as a means of boosting employees’ creativity.
The academic symposium was divided into a keynote speech, paper presentations from each field, and a poster fair.
Professor Dae-Sik Kim from KAIST delivered a keynote speech on “Neuroscience and Creativity,” offering a glimpse of the world from a neuroscience perspective. Jae-min Lee, a researcher at Samsung Electronics, provided an industrial case study, “Application of TRIZ for the Improvement of Refrigerator.” Professor Jung-Seok Hyun from Jeju University and Dr. Jung-Ho Shin from E-Triz System presented their application of TRIZ on “Limitless Imagination and Invention Class for the Elementary School Students.” Altogether, 36 other research papers and case studies were presented at the symposium.
Dr. Dong-ryul Yang, President of KSCA, said, “This academic symposium allows us to discuss a range of innovative case studies that utilize TRIZ in industrial and educational fields, from which we can learn good lessons and practices.”
2016.01.19 View 7283