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KAIST Team Develops Semi-Transparent Solar Cells with Thermal Mirror Capability
A research team led by KAIST and Sungkyunkwan University professors has created semi-transparent perovskite solar cells that demonstrate high-power conversion efficiency and transmit visible light while blocking infrared light, making them great candidates for solar windows. Modern architects prefer to build exteriors designed with glass mainly from artistic or cost perspectives. Scientists, however, go one step further and see opportunities from its potential ability to harness solar energy. Researchers have thus explored ways to make solar cells transparent or semi-transparent as a substitute material for glass, but this has proven to be a challenging task because solar cells need to absorb sunlight to generate electricity, and when they are transparent, it reduces their energy efficiency. Typical solar cells today are made of crystalline silicon, but it is difficult to make them translucent. Semi-transparent solar cells under development use, for example, organic or dye-sensitized materials, but compared to crystalline silicon-based cells, their power-conversion efficiencies are relatively low. Perovskites are hybrid organic-inorganic halide-based photovoltaic materials, which are cheap to produce and easy to manufacture. They have recently received much attention as the efficiency of perovskite solar cells has rapidly increased to the level of silicon technologies in the past few years. Using perovskites, a Korean research team led by Professor Seunghyup Yoo of the Electrical Engineering School at KAIST and Professor Nam-Gyu Park of the Chemical Engineering School at Sungkyunkwan University developed a semi-transparent solar cell that is highly efficient and, additionally, functions very effectively as a thermal-mirror. The team has developed a top transparent electrode (TTE) that works well with perovskite solar cells. In most cases, a key to success in realizing semi-transparent solar cells is to find a TTE that is compatible with a given photoactive material system, which is also the case for perovskite solar cells. The proposed TTE is based on a multilayer stack consisting of a metal film sandwiched between a high refractive-index (high-index) layer and an interfacial buffer layer. This TTE, placed as a top-most layer, can be prepared without damaging ingredients used in perovskite solar cells. Unlike conventional transparent electrodes focusing only on transmitting visible light, the proposed TTE plays the dual role of passing through visible light while reflecting infrared rays. The semi-transparent solar cells made with the proposed TTEs exhibited average power conversion efficiency as high as 13.3% with 85.5% infrared rejection. The team believes that if the semi-transparent perovskite solar cells are scaled up for practical applications, they can be used in solar windows for buildings and automobiles, which not only generate electrical energy but also enable the smart heat management for indoor environments, thereby utilizing solar energy more efficiently and effectively. This result was published as a cover article in the July 20, 2016 issue of Advanced Energy Materials. The research paper is entitled “Empowering Semi-transparent Solar Cells with Thermal-mirror Functionality.” (DOI: 10.1002/aenm.201502466) The team designed the transparent electrode (TE) stack in three layers: A thin-film of silver (Ag) is placed in between the bottom interfacial layer of molybdenum trioxide (MoO3) and the top high-index dielectric layer of zinc sulfide (ZnS). Such a tri-layer approach has been known as a means to increase the overall visible-light transmittance of metallic thin films via index matching technique, which is essentially the same technique used for anti-reflection coating of glasses except that the present case involves a metallic layer. Traditionally, when a TE is based on a metal film, such as Ag, the film should be extremely thin, e.g., 7-12 nanometers (nm), to obtain transparency and, accordingly, to transmit visible light. However, the team took a different approach in this research. They made the Ag TE two or three times thicker (12-24 nm) than conventional metal films and, as a result, it reflected more infrared light. The high refractive index of the ZnS layer plays an essential role in keeping the visible light transmittance of the proposed TTE high even with the relatively thick Ag film when its thickness is carefully optimized for maximal destructive interference, leading to low reflectance (and thus high transmittance) within its visible light range. The team confirmed the semi-transparent perovskite solar cell’s thermal-mirror function through an experiment in which a halogen lamp illuminated an object for five minutes through three mediums: a window of bare glass, automotive tinting film, and the proposed semi-transparent perovskite solar cell. An infrared (IR) camera took thermal images of the object as well as that of each window’s surface. The object’s temperature, when exposed through the glass window, rose to 36.8 Celsius degrees whereas both the tinting film and the cell allowed the object to remain below 27 Celsius degrees. The tinting film absorbs light to block solar energy, so the film’s surface became hot as it was continuously exposed to the lamp light, but the proposed semi-transparent solar cell stayed cool since it rejects solar heat energy by reflection, rather than by absorption. The total solar energy rejection (TSER) of the proposed cell was as high as 89.6%. Professor Yoo of KAIST said, “The major contributions of this work are to find transparent electrode technology suitable for translucent perovskite cells and to provide a design approach to fully harness the potential it can further deliver as a heat mirror in addition to its main role as an electrode. The present work can be further fine-tuned to include colored solar cells and to incorporate flexible or rollable form factors, as they will allow for greater design freedom and thus offer more opportunities for them to be integrated into real-world objects and structures such as cars, buildings, and houses.” The lead authors are Hoyeon Kim and Jaewon Ha, both Ph.D. candidates in the School of Electrical Engineering at KAIST, and Hui-Seon Kim, a student in the School of Chemical Engineering at Sungkyunkwan University. This research was supported mainly by the Climate Change Research Hub Program of KAIST. Picture 1: Semi-transparent Perovskite Solar Cell This picture shows a prototype of a semi-transparent perovskite solar cell with thermal-mirror functionality. Picture 2: A Heat Rejection Performance Comparison Experiment This picture presents thermal images taken by an infrared camera for comparing the heat rejection performance of bare glass, automotive tinting film, and a semi-transparent perovskite solar cell after being illuminated by a halogen lamp for five minutes.
2016.08.02
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KAIST Develops Transparent Oxide Thin-Film Transistors
With the advent of the Internet of Things (IoT) era, strong demand has grown for wearable and transparent displays that can be applied to various fields such as augmented reality (AR) and skin-like thin flexible devices. However, previous flexible transparent displays have posed real challenges to overcome, which are, among others, poor transparency and low electrical performance. To improve the transparency and performance, past research efforts have tried to use inorganic-based electronics, but the fundamental thermal instabilities of plastic substrates have hampered the high temperature process, an essential step necessary for the fabrication of high performance electronic devices. As a solution to this problem, a research team led by Professors Keon Jae Lee and Sang-Hee Ko Park of the Department of Materials Science and Engineering at the KAIST has developed ultrathin and transparent oxide thin-film transistors (TFT) for an active-matrix backplane of a flexible display by using the inorganic-based laser lift-off (ILLO) method. Professor Lee’s team previously demonstrated the ILLO technology for energy-harvesting (Advanced Materials, February 12, 2014) and flexible memory (Advanced Materials, September 8, 2014) devices. The research team fabricated a high-performance oxide TFT array on top of a sacrificial laser-reactive substrate. After laser irradiation from the backside of the substrate, only the oxide TFT arrays were separated from the sacrificial substrate as a result of reaction between laser and laser-reactive layer, and then subsequently transferred onto ultrathin plastics ( thickness). Finally, the transferred ultrathin-oxide driving circuit for the flexible display was attached conformally to the surface of human skin to demonstrate the possibility of the wearable application. The attached oxide TFTs showed high optical transparency of 83% and mobility of even under several cycles of severe bending tests. Professor Lee said, “By using our ILLO process, the technological barriers for high performance transparent flexible displays have been overcome at a relatively low cost by removing expensive polyimide substrates. Moreover, the high-quality oxide semiconductor can be easily transferred onto skin-like or any flexible substrate for wearable application.” These research results, entitled “Skin-Like Oxide Thin-Film Transistors for Transparent Displays,” (http://onlinelibrary.wiley.com/doi/10.1002/adfm.201601296/abstract) were the lead article published in the July 2016 online issue of Wiley’s Advanced Functional Materials. ### References [1] Advanced Materials, February 12, 2014, Highly-efficient, Flexible Piezoelectric PZT Thin Film Nanogenerator on Plastic Substrates (http://onlinelibrary.wiley.com/doi/10.1002/adma.201305659/abstract) [2] Advanced Materials, September 8, 2014, Flexible Crossbar-structured Resistive Memory Arrays on Plastic Substartes via Inorganic-based Laser Lift-off (http://onlinelibrary.wiley.com/doi/10.1002/adma.201402472/abstract) Picture 1: A Schamatic Image of Ultrathin, Flexible, and Transparent Oxide Thin-film Transistors This image shows ultrathin, flexible, and transparent oxide thin-film transistors produced via the ILLO process. Picture 2: Application of Uultrathin, Flexible, and Transparent Oxide Thin-film Transistors This picture shows ultrathin, flexible, and transparent oxide thin-film transistors attached to a jumper sleeve and human skin.
2016.08.01
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ICISTS Hosts the International Interdisciplinary Conference
A KAIST student organization, The International Conference for the Integration of Science, Technology and Society (ICISTS), will host ICISTS 2016 at the Hotel ICC in Daejeon from 3 to 7 August with the participation of around 300 Korean and international students. ICISTS was first established in 2005 to provide an annual platform for delegates and speakers to discuss the integration and the convergence of science, technology, and society regardless of their academic backgrounds. This year’s conference, with the theme of “Beyond the Center,” emphasizes the ways in which technological advancements can change central organizations in areas such as financial technology, healthcare, and global governance. The keynote speakers include Dennis Hong, a developer of the first automobile for the blind and a professor of the Mechanical and Aerospace Engineering Department at UCLA, Dor Konforty, a founder and a CEO of SNS platform Synereo, and Marzena Rostek, a professor of Economics at the University of Wisconsin-Madison. Other notable speakers include: Gi-Jung Jung, Head of the National Fusion Research Institute; Janos Barberis, Founder of FinTech HK; Tae-Hoon Kim, CEO and Founder of Rainist; Gulrez Shah Azhar, Assistant Policy Analyst at RAND Corporation; Thomas Concannon, Senior Policy Researcher at RAND Corporation; Leah Vriesman, Professor at the School of Public Health, UCLA; and Bjorn Cumps, Professor of Management Practice at Vlerick Business School in Belgium. The conference consists of keynote speeches, panel discussions, open talks, experience sessions, team project presentations, a culture night, and a beer party, at which all participants will be encouraged to interact with speakers and delegates and to discuss the topics of their interest. Han-Kyul Jung, ICISTS’s Head of Public Relations, said, “This conference will not only allow the delegates to understand the trends of future technology, but also be an opportunity for KAIST students to form valuable contacts with students from around the world.” For more information, please go to www.icists.org.
2016.07.20
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Professor Kun-pyo Lee Appointed Honorary Fellow of the Design Research Society
Founded in the United Kingdom (UK) in 1966, the Design Research Society is an international academic organization that promotes excellence in design and supports the interests of the design research community. Professor Kun-pyo Lee of the Industrial Design Department at KAIST received his honorary fellowship from the Society at its 50th international conference held from June 27, 2016 to July 3, 2016 in Brighton, UK. The Society recognized Professor Lee’s academic achievements and his contribution to the advancement of design research nationally and globally. To date, only eight researchers have received honorary fellowships from the Society, and he is the first Asian to become an honorary fellow. Professor Lee has worked at KAIST for more than 30 years as a professor in industrial engineering and served on various important positions such as the president of the Korean Society of Design Science, the president of the International Association of Societies of Design Research, an executive vice president of the Corporate Design Center at LG Electronics, and an advisory board member for Human-centered Design Network in Japan and UXnet in the United States. By introducing the concept of user experience (UX) in Korea for the first time, he developed this field while focusing on user-centered designs to optimize interactive digital products as well as interaction design to create mental and physical interfaces between people and interactive digital products, services, and systems. Professor Lee said, “I am pleased to become an honorary fellow of the Design Research Society. For quiet some time, industrial design remained in the domain of practical studies, lacking the kind of support needed to grow as an independent academic and research discipline, but this has changed rapidly in recent years. I will continue to remain actively involved in the development of industrial design engineering in Korea and the world.”
2016.07.19
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KAIST and KTH Establish a Dual Degree Program in Nuclear Engineering
Professor Man-Sung Im, head of the Nuclear and Quantum Engineering Department at KAIST and Director Waclaw Gudowski of the Physics Department at the KTH Royal Institute of Technology in Stockholm (KTH), Sweden, agreed to establish a dual master’s degree program in the field of nuclear and quantum engineering, and signed the agreement on July 4, 2016 at the Faculty Club on the KAIST campus. Following the first joint degree program in mechanical engineering in 2014, this is the second dual degree program created between the two universities. Under the agreement, which will be effective beginning in the 2016 fall semester, KAIST and KTH will exchange students, confer students dual degrees when they earn the required number of credits, and support financial aid for exchange students. Dean Im said, “The two schools have enjoyed an excellent reputation in nuclear and quantum engineering, and offering students more opportunities to study abroad at the other university will produce synergistic effects for the growth of the two schools' education and research.” Founded in 1827, KTH is regarded one of the most prestigious universities in Northern Europe. Professor Man-Sung Im of KAIST’s Nuclear and Quantum Engineering (pictured on the left) and Director Waclaw Gudowski of KTH’s Physics Department are shaking hands after signing the agreement for the dual master’s degree program.
2016.07.05
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Synthesized Microporous 3D Graphene-like Carbons
Distinguished Professor Ryong Ryoo of the Chemistry Department at KAIST, who is also the Director of the Center for Nanomaterials and Carbon Materials at the Institute for Basic Science (IBS), and his research team have recently published their research results entitled "Lanthanum-catalysed Synthesis of Microporous 3D Graphene-like Carbons in a Zeolite Template" on June 29, 2016 in Nature on a new method to synthesize carbons having graphene structures with 3D periodic micropores, a trait resulted from using a zeolite as a template for the synthesis. The research team expects this technology to find a range of useful applications such as in batteries and catalysts. Graphene, an allotrope of carbon, which was discovered more than a decade ago, has led to myriad research that seeks to unlock its vast potential. Zeolites, commonly used microporous solid catalysts in the petrochemical industry, have recently attracted attention in the field of material science as a template for carbon synthesis. Zeolites’ individual crystal is distinguished by its unique 1 nanometer (nm)-size pore structures. These structures facilitate the accommodation of carbon nanotubes inside zeolites. In their paper, the research team showed that these nanoporous systems are an ideal template for the carbon synthesis of three-dimensional (3D) graphene architecture, but zeolite pores are too small to accommodate bulky molecular compounds like polyaromatic and furfuryl alcohol that are often used in carbon synthesis. Small molecules like ethylene and acetylene can be used as a carbon source to achieve successful carbonization within zeolite pores, but it comes at a great cost. The high temperatures required for the synthesis cause reactions of carbons being deposited randomly on the external surfaces of zeolites as well as their internal pore walls, resulting in coke deposition and consequently, causing serious diffusion limitations in the zeolite pores. The team from the IBS Center for Nanomaterials and Carbon Materials solved this conundrum with a novel approach. First author Dr. KIM Kyoungsoo explains: “The zeolite-template carbon synthesis has existed for a long time, but the problem with temperatures has foiled many scientists from extracting their full potential. Here, our team sought to find the answer by embedding lanthanum ions (La3+), a silvery-white metal element, in zeolite pores. This lowers the temperature required for the carbonization of ethylene or acetylene. Graphene-like sp2 carbon structures can be selectively formed inside the zeolite template, without carbon deposition at the external surfaces. After the zeolite template is removed, the carbon framework exhibits the electrical conductivity two orders of magnitude higher than amorphous mesoporous carbon, which is a pretty astonishing result. This highly efficient synthesis strategy based on the lanthanum ions renders the carbon framework to be formed in pores with a less than 1 nm diameter, just like as easily reproducible as in mesoporous templates. This provides a general method to synthesize carbon nanostructures with various topologies corresponding to the template zeolite pore topologies, such as FAU, EMT, beta, LTL, MFI, and LTA. Also, all the synthesis can be readily scaled up, which is important for practical applications in areas of batteries, fuel storage, and other zeolite-like catalyst supports.” The research team began their experiment by utilizing La3+ ions. Dr. KIM elucidates why this silvery-white element proved so beneficial to the team, “La3+ ions are unreducible under carbonization process condition, so they can stay inside the zeolite pores instead of moving to the outer zeolite surface in the form of reduced metal particles. Within the pores, they can stabilize ethylene and the pyrocondensation intermediately to form a carbon framework in zeolites.” In order to test this hypothesis, the team compared the amount of carbon deposited in La3+-containing form of Y zeolite (LaY) sample against a host of other samples such as NaY and HY. The experimental results indicate that all the LaY, NaY, and HY zeolite samples show rapid carbon deposition at 800°C. However, as the temperature decreases, there appears to be a dramatic difference between the different ionic forms of zeolites. At 600°C, the LaY zeolite is still active as a carbon deposition template. In contrast, both NaY and HY lose their carbon deposition functions almost completely. The results, according to their paper published in Nature, highlight a catalytic effect of lanthanum for carbonization. By making graphene with 3D periodic nanoporous architectures, it promises a wide range of useful applications such as in batteries and catalysts but due to the lack of efficient synthetic strategies, such applications have not yet been successful. By taking advantage of the pore-selective carbon filling at decreased temperatures, the synthesis can readily be scaled up for studies requiring bulk quantities of carbon, in particular high electrical conductivity, which is a highly sought aspect for the production of batteries. YouTube Link: https://youtu.be/lkNiHiB8lBk Image 1: (Top to Bottom) Zeolite Template: Microporous Aluminosilicate; Zeolite ion exchanged with La3+ ions in aqueous solution; and Zeolite Template with La3+ ions Image 2: (Top to Bottom) Catalytic carbonization progressed at La3+ ions-exchanged sites using ethylene as a carbon precursor. Carbon is highlighted in grey; Zeolite template removed in an acid solution (HF/ HCl); Microporous 3D graphene-like carbon
2016.07.01
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Top 10 Emerging Technologies by World Economic Forum
The World Economic Forum’s Meta-Council on Emerging Technologies announced its annual list of breakthrough technologies, the “Top 10 Emerging Technologies of 2016,” on June 23, 2016. The Meta-Council chose the top ten technologies based on the technologies’ potential to improve lives, transform industries, and safeguard the planet. The research field of systems metabolic engineering, founded by Distinguished Professor Sang Yup Lee of the Chemical and Biomolecular Engineering Department at KAIST, was also citied. Systems metabolic engineering, which combines elements of synthetic biology, systems biology, and evolutionary engineering, offers a sustainable process for the production of useful chemicals in an environmentally friendly way from plants such as inedible biomass, reducing the need of using fossil fuels. Details about the list follow below: https://www.weforum.org/press/2016/06/battery-powered-villages-sociable-robots-rank-among-top-10-emerging-technologies-of-2016 The picture below shows the “systems metabolic engineering of E. coli for the production of PLGA." PLGA is poly(lactate-co-glycolate), which is widely used for biomedical applications, and has been made by chemical synthesis. Now it is possible to produce PLGA eco-friendly by one-step fermentation of a gut bacterium which is developed through systems metabolic engineering.
2016.06.27
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KAIST to Participate in Summer Davos Forum 2016 in China
A group of KAIST researchers will share their insights on the future and challenges of the current technological innovations impacting all aspects of society, while showcasing their research excellence in artificial intelligence and robotics. Scientific and technological breakthroughs are more important than ever as key agents to drive social, economic, and political changes and advancements in today’s world. The World Economic Forum (WEF), an international organization that provides one of the broadest engagement platforms to address issues of major concern to the global community, will discuss the effects of these breakthroughs at its 10th Annual Meeting of the New Champions, a.k.a., the Summer Davos Forum, in Tianjin, China, June 26-28, 2016. Three professors from the Korea Advanced Institute of Science and Technology (KAIST) will join the Annual Meeting and offer their expertise in the fields of biotechnology, artificial intelligence, and robotics to explore the conference theme, “The Fourth Industrial Revolution and Its Transformational Impact.” The Fourth Industrial Revolution, a term coined by WEF founder, Klaus Schwab, is characterized by a range of new technologies that fuse the physical, digital, and biological worlds, such as the Internet of Things, cloud computing, and automation. Distinguished Professor Sang Yup Lee of the Chemical and Biomolecular Engineering Department will speak at the Experts Reception to be held on June 25, 2016 on the topic of “The Summer Davos Forum and Science and Technology in Asia.” On June 27, 2016, he will participate in two separate discussion sessions. In the first session entitled “What If Drugs Are Printed from the Internet?,” Professor Lee will discuss the impacts of advancements in biotechnology and 3D printing technology on the future of medicine with Nita A. Farahany, a Duke University professor. Clare Matterson, the Director of Strategy at Wellcome Trust in the United Kingdom, will serve as the moderator. The discussants will note recent developments made in the way patients receive their medicine, for example, downloading drugs directly from the internet and the production of yeast strains to make opioids for pain treatment through systems metabolic engineering. They will also suggest how these emerging technologies will transform the landscape of the pharmaceutical industry in the years to come. In the second session, “Lessons for Life,” Professor Lee will talk about how to nurture life-long learning and creativity to support personal and professional growth necessary in an era of the new industrial revolution. During the Annual Meeting, Professors Jong-Hwan Kim of the Electrical Engineering School and David Hyunchul Shim of the Aerospace Department will host, together with researchers from Carnegie Mellon University and AnthroTronix, an engineering research and development company, a technological exhibition on robotics. Professor Kim, the founder of the internally renowned Robot World Cup, will showcase his humanoid soccer-playing micro-robots and display their various cutting-edge technologies such as imaging processing, artificial intelligence, walking, and balancing. Professor Shim will present a human-like robotic piloting system, PIBOT, which autonomously operates a simulated flight program by employing control sticks and guiding an airplane from takeoff to landing. In addition, the two professors will join Professor Lee, who is also a moderator, to host a KAIST-led session on June 26, 2016, entitled “Science in Depth: From Deep Learning to Autonomous Machines.” Professors Kim and Shim will explore new opportunities and challenges in their fields from machine learning to autonomous robotics, including unmanned vehicles and drones. Since 2011, KAIST has participated in the World Economic Forum’s two flagship conferences, the January and June Davos Forums, to introduce outstanding talents, share their latest research achievements, and interact with global leaders. KAIST President Steve Kang said, “It is important for KAIST to be involved in global forums that identify issues critical to humanity and seek answers to solve them, and where our skills and knowledge in science and technology can play a meaningful role. The Annual Meeting in China will become another venue to accomplish this.”
2016.06.27
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Unveiling the Distinctive Features of Industrial Microorganism
KAIST researchers have sequenced the whole genome of Clostridium tyrobutyricum, which has a higher tolerance to toxic chemicals, such as 1-butanol, compared to other clostridial bacterial strains. Clostridium tyrobutyricum, a Gram-positive, anaerobic spore-forming bacterium, is considered a promising industrial host strain for the production of various chemicals including butyric acid which has many applications in different industries such as a precursor to biofuels. Despite such potential, C. tyrobutyricum has received little attention, mainly due to a limited understanding of its genotypic and metabolic characteristics at the genome level. A Korean research team headed by Distinguished Professor Sang Yup Lee of the Chemical and Biomolecular Engineering Department at the Korea Advanced Institute of Science and Technology (KAIST) deciphered the genome sequence of C. tyrobutyricum and its proteome profiles during the course of batch fermentation. As a result, the research team learned that the bacterium is not only capable of producing a large amount of butyric acid but also can tolerate toxic compounds such as 1-butanol. The research results were published in mBio on June 14, 2016. The team adopted a genoproteomic approach, combining genomics and proteomics, to investigate the metabolic features of C. tyrobutyricum. Unlike Clostridium acetobutylicum, the most widely used organism for 1-butanol production, C. tyrobutyricum has a novel butyrate-producing pathway and various mechanisms for energy conservation under anaerobic conditions. The expression of various metabolic genes, including those involved in butyrate formation, was analyzed using the “shotgun” proteome approach. To date, the bio-based production of 1-butanol, a next-generation biofuel, has relied on several clostridial hosts including C. acetobutylicum and C. beijerinckii. However, these organisms have a low tolerance against 1-butanol even though they are naturally capable of producing it. C. tyrobutyricum cannot produce 1-butanol itself, but has a higher 1-butanol-tolerance and rapid uptake of monosaccharides, compared to those two species. The team identified most of the genes involved in the central metabolism of C. tyrobutyricum from the whole-genome and shotgun proteome data, and this study will accelerate the bacterium’s engineering to produce useful chemicals including butyric acid and 1-butanol, replacing traditional bacterial hosts. Professor Lee said, “The unique metabolic features and energy conservation mechanisms of C. tyrobutyricum can be employed in the various microbial hosts we have previously developed to further improve their productivity and yield. Moreover, findings on C. tyrobutyricum revealed by this study will be the first step to directly engineer this bacterium.” Director Jin-Woo Kim at the Platform Technology Division of the Ministry of Science, ICT and Future Planning of Korea, who oversees the Technology Development Program to Solve Climate Change, said, “Over the years, Professor Lee’s team has researched the development of a bio-refinery system to produce natural and non-natural chemicals with the systems metabolic engineering of microorganisms. They were able to design strategies for the development of diverse industrial microbial strains to produce useful chemicals from inedible biomass-based carbon dioxide fixation. We believe the efficient production of butyric acid using a metabolic engineering approach will play an important role in the establishment of a bioprocess for chemical production.” The title of the research paper is “Deciphering Clostridium tyrobutyricum Metabolism Based on the Who-Genome Sequence and Proteome Analyses.” (DOI: 10.1128/mBio.00743-16) The lead authors are Joungmin Lee, a post-doctoral fellow in the BioProcess Research Center at KAIST, currently working in CJ CheilJedang Research Institute; Yu-Sin Jang, a research fellow in the BioProcess Research Center at KAIST, currently working at Gyeongsang National University as an assistant professor; and Mee-Jung Han, an assistant professor in the Environmental Engineering and Energy Department at Dongyang University. Jin Young Kim, a senior researcher at the Korea Basic Science Institute, also participated in the research. This research was supported by the Technology Development Program to Solve Climate Change’s research project entitled “Systems Metabolic Engineering for Biorefineries” from the Ministry of Science, ICT and Future Planning through the National Research Foundation of Korea (NRF-2012M1A2A2026556). Schematic Diagram of C. tyrobutyricum’s Genome Sequence and Its Proteome Profiles The picture below shows the complete genome sequence, global protein expression profiles, and the genome-based metabolic characteristics during batch fermentation of C. tyrobutyricum.
2016.06.20
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KAIST and McKinsey Korea Agreed to Cultivate Management Leaders
KAIST and McKinsey Korea signed a memorandum of understanding (MOU) for the “Joint Research on Innovative Instructional Method to Cultivate Future Management Leaders” on April 8, 2016, at the SUPEX Management Hall of KAIST Management School in Seoul. Under the MOU, both organizations will cooperate in the following research areas: management strategies to overcome the low growth of Korean economy, instructional methods to foster leaders in the field of business and management, and innovative management systems for business. President Kang said, “We are pleased to work with McKinsey, a worldwide management consulting firm, to foster leaders in science and business. As we see more demanding challenges of managing and leading science-based businesses today, this alliance is indeed timely and will be very helpful.”
2016.04.15
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KAIST Hosts the 2016 IPFGRU
More than 120 senior representatives from 65 universities around the world will convene this month in Seoul to discuss the social responsibilities of higher education and strategic global partnerships among academia, research, and industry to advance socio-economic values. Higher education as a driver of change to address the social and global challenges facing humanity in the 21st century has never been as important as it is today. KAIST will raise the topic of higher education as a driver of social change, innovation, and entrepreneurship with the heads of global universities at its seventh international forum to be held on April 11-12, 2016 at the Grand Hyatt Hotel in Seoul, the Republic of Korea. The 2016 International Presidential Forum on Global Research Universities (IPFGRU) will bring over 120 presidents and vice presidents of 65 research universities and institutes from 36 nations together to discuss the theme of “Social Responsibilities of Higher Education and Strategic Global Partnership.” Presidents Sung-Mo Kang of KAIST, Jacques Biot of École Polytechnique in France, and Peretz Lavie of the Technion-Israel Institute of Technology will address the conference as plenary speakers. President Kang will speak about KAIST’s initiatives to produce creative talents through student-centered education, entrepreneurship curricula, and the integration of humanities into cutting-edge research programs. His presentation, titled “The Fostering of Creative Talents and the Social Responsibility of Research Universities in the New Era,” introduces KAIST’s educational philosophy which can be represented as π. A broad range of understanding in basic disciplines (the horizontal line) is supported with one prong of in-depth knowledge in a chosen field and the other in entrepreneurial spirit. KAIST graduates have demonstrated extraordinary leadership in research, academia, business, and public service. Nearly 25% of the research and development personnel at Samsung Electronics are KAIST Ph.D. holders. President Kang also describes KAIST’s latest endeavor to turn a university-led entrepreneurial activity into a stable business based on research outcomes and campus innovations. The K-School, a one-year master’s degree program on entrepreneurship and innovation, has just launched and is expecting to receive its first batch of students this fall. The K-School is envisioned to continue the university’s legacy as a major feeder for startups in Korea. President Lavie will give a talk on “Fostering an Innovation and Entrepreneurship (I&E) Ecosystem in Israel,” in which he describes how the Technion-Israel Institute has become integral to the foundation of the nation’s I&E platform. Since its establishment in 1912, the university has become a key player in the growth of Israel’s industry, science, and technology while nurturing the majority of the nation’s top-notch researchers, innovators, and entrepreneurs. Technion graduates have created more than 2,000 companies in Israel alone, generating 100,000 jobs and USD 30 billion through mergers and acquisitions. President Biot will offer his insights into how the future of global research universities will be widely impacted by the emergence of disruptions triggered by the Fourth Industrial Revolution. In his speech entitled “How to Prepare Our Universities for the New Era of Industry 4.0,” he emphasizes that universities should take multi-disciplinary approaches to tackle societal challenges given the complexity of today’s problems ranging from climate change to energy crises, pandemic diseases, and poverty. He argues that universities should identify the needs of students in “Generation Z” who, from birth, have been heavily exposed to the Internet and digital technologies and, thus, universities should develop new educational systems (i.e., University 4.0.) to better prepare these students to cope with Industry 4.0. The IPFGRU consists of presentations and discussions addressing the following sub-topics: - Seeking a New Model of Research Universities in a New Era: This session will explore the role of research universities as both innovation drivers and growth engines in an age of robotics, globalization, and digitally-driven markets. In addition, speakers will discuss how to prepare universities for the Industry 4.0 era, and how multidisciplinary approaches and open innovations will play a large part in facilitating translational research and technology transfer. - Shared Challenges and Responsibilities from a Global Perspective: Universities will share their strategies, policies, and practices to respond to critical issues facing local and global communities such as youth unemployment, the environment, energy, inequality, and entrepreneurship. - Strategic Global Partnerships for Sustainable Development: Panelists will discuss how to build productive and sustainable partnerships that can generate synergies between education and research. - Insights into Higher Education: Trends and Development: Participants will examine how universities can stay relevant in an increasingly competitive higher education sector and can assist students to better adapt to opportunities and challenges posed by the new industry of digital transformation and exponentially-growing technologies. Sung-Hyon Myaeng, the Associate Vice President of the International Office at KAIST and a Co-chair of the 2016 IPFGRU said, “The IPFGRU was established in 2008 to promote excellence and innovation in higher education with presidents of leading research universities and key policy-makers in the private and public sectors from across the world. Since then, it has served as one of the largest university gatherings in Asia, allowing participants to cooperate and share their expertise, ideas, and best practices taking place in academia, industry, and government.” “This year’s meeting has recorded the largest number of universities participating, including 28 European schools, 20 Asian institutions, and 8 schools from the Americas, which I believe reflects a sense of urgency that global universities share. One way or another, we must adapt to the rapidly transforming educational and research environment encompassing higher learning,” added Myaeng. For more information, go to http://forum.kaist.ac.kr.
2016.04.08
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Next-Generation Holographic Microscope for 3D Live Cell Imaging
KAIST researchers have developed a revolutionary bio-medical imaging tool, the HT-1, to view and analyze cells, which is commercially available. Professor YongKeun Park of the Physics Department at KAIST and his research team have developed a powerful method for 3D imaging of live cells without staining. The researchers announced the launch of their new microscopic tool, the holotomography (HT)-1, to the global marketplace through a Korean start-up that Professor Park co-founded, TomoCube (www.tomocube.com). Professor Park is a leading researcher in the field of biophotonics and has dedicated much of his research career to working on digital holographic microscopy technology. He collaborated with TomoCube’s R&D team to develop a state-of-the-art, 2D/3D/4D holographic microscope that would allow a real-time label-free visualization of biological cells and tissues. The HT is an optical analogy of X-ray computed tomography (CT). Both X-ray CT and HT share the same physical principle—the inverse of wave scattering. The difference is that HT uses laser illumination whereas X-ray CT uses X-ray beams. From the measurement of multiple 2D holograms of a cell, coupled with various angles of laser illuminations, the 3D refractive index (RI) distribution of the cell can be reconstructed. The reconstructed 3D RI map provides structural and chemical information of the cell including mass, morphology, protein concentration, and dynamics of the cellular membrane. The HT enables users to quantitatively and non-invasively investigate the intrinsic properties of biological cells, for example, dry mass and protein concentration. Some of the research team’s breakthroughs that have leveraged HT’s unique and special capabilities can be found in several recent publications, including a lead article on the simultaneous 3D visualization and position tracking of optically trapped particles which was published in Optica on April 20, 2015. Current fluorescence confocal microscopy techniques require the use of exogenous labeling agents to render high-contrast molecular information. Therefore, drawbacks include possible photo-bleaching, photo-toxicity, and interference with normal molecular activities. Immune or stem cells that need to be reinjected into the body are considered particularly difficult to employ with fluorescence microscopy. “As one of the two currently available, high-resolution tomographic microscopes in the world, I believe that the HT-1 is the best in class regarding specifications and functionality. Users can see 3D/4D live images of cells, without fixing, coating or staining cells. Sample preparation times are reduced from a few days or hours to just a few minutes,” said Professor Park. Two Korean hospitals, Seoul National University Hospital in Bundang and Boramae Hospital in Seoul, are using this microscope currently. The research team has also introduced the HT-1 at the Photonics West Exhibition 2016 that took place on February 16-18 in San Francisco, USA. Professor Park added, “Our technology has set a new paradigm for cell observation under a microscope. I expect that this tomographic microscopy will be more widely used in future in various areas of pharmaceuticals, neuroscience, immunology, hematology, and cell biology.” Figure 1: HT-1 and Its Specifications Figure 2: 3D Images of Representative Biological Cells Taken with the HT-1
2016.03.29
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